DDS Formulations Used in the Otolaryngology Field: Characteristics of Pharmacokinetics and Side Effects

The Drug Delivery System (DDS) technology has attracted much attention since the early 1970s. This technology enabled the development of novel drugs including sustained-release and prodrug preparations. DDS has been linked to improvement of drug efficacy and drug applicability to clinical practice....

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Published inThe Journal of Japan Society for Infection and Aerosol in Otorhinolaryngology Vol. 8; no. 3; pp. 180 - 183
Main Authors Iwamoto, Takuya, Uebayashi, Rie, Kawase, Ryousuke
Format Journal Article
LanguageJapanese
Published Japan Society for Infection and Aerosol in Otorhinolaryngology 20.11.2020
日本耳鼻咽喉科感染症・エアロゾル学会
Subjects
Drug Delivery System (DDS)
Emedastine fumarate
Fluticasone propionate
Pharmacokinetics
Sodium cromoglycate
エメダスチンフマル酸塩
クロモグリク酸ナトリウム
ドラッグデリバリーシステム
フルチカゾンプロピオン酸エステル
薬物動態
Online AccessGet full text
ISSN2188-0077
2434-1932
DOI10.24805/jjsiao.8.3_180

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Abstract The Drug Delivery System (DDS) technology has attracted much attention since the early 1970s. This technology enabled the development of novel drugs including sustained-release and prodrug preparations. DDS has been linked to improvement of drug efficacy and drug applicability to clinical practice. Understanding the pharmacokinetics and side effects of a drug is particularly critical in patient-tailored medicine. In this article, we described the characteristic pharmacokinetics and side effects of DDS drugs commonly used in the field of otolaryngology.
AbstractList The Drug Delivery System (DDS) technology has attracted much attention since the early 1970s. This technology enabled the development of novel drugs including sustained-release and prodrug preparations. DDS has been linked to improvement of drug efficacy and drug applicability to clinical practice. Understanding the pharmacokinetics and side effects of a drug is particularly critical in patient-tailored medicine. In this article, we described the characteristic pharmacokinetics and side effects of DDS drugs commonly used in the field of otolaryngology.
The Drug Delivery System (DDS) technology has attracted much attention since the early 1970s. This technology enabled the development of novel drugs including sustained-release and prodrug preparations. DDS has been linked to improvement of drug efficacy and drug applicability to clinical practice. Understanding the pharmacokinetics and side effects of a drug is particularly critical in patient-tailored medicine. In this article, we described the characteristic pharmacokinetics and side effects of DDS drugs commonly used in the field of otolaryngology. ドラックデリバリーシステム（Drug Delivery System: DDS）技術は1970年代より注目され始め，徐放性製剤やプロドラック化された製剤を含む新薬の開発が可能となり，治療の有効性や利便性向上に繋がっている．薬剤の体内動態や副作用を理解することが，個々の患者に合わせた薬剤を選択していくためには重要となる．そこで，本稿では，耳鼻咽喉科領域でよく使用されるDDS製剤について，薬物動態や副作用発現状況の違いについて紹介する．
Author Iwamoto, Takuya
Kawase, Ryousuke
Uebayashi, Rie
Author_FL 岩本 卓也
川瀬 亮介
上林 里絵
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  organization: Department of Pharmacy, Mie University Hospital
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DocumentTitleAlternate 耳鼻咽喉科領域で使用されるDDS製剤：薬物動態や副作用の特徴
DocumentTitle_FL 耳鼻咽喉科領域で使用されるDDS製剤：薬物動態や副作用の特徴
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PublicationTitle The Journal of Japan Society for Infection and Aerosol in Otorhinolaryngology
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日耳鼻感染症エアロゾル会誌
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日耳鼻感染症エアロゾル会誌
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日本耳鼻咽喉科感染症・エアロゾル学会
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References 6) インタール®点鼻液　インタビューフォーム　2012年10月 (第7版).
2) アレサガ®テープ　インタビューフォーム　2019年5月 (第4版).
1) 図解で学ぶDDS―薬物治療の最適化を目指す先端創薬技術. 橋本　充 監, 高倉喜信 編, じほう; 2010 Section 1, 2.
4) インタール®細粒　インタビューフォーム　2012年10月 (第5版).
3) レミカット®カプセル　インタビューフォーム　2019年4月 (第8版).
5) インタール®エアロゾル　インタビューフォーム　2012年10月 (第9版).
7) フルナーゼ®点鼻液　インタビューフォーム　2019年4月 (第15版).
References_xml – reference: 2) アレサガ®テープ　インタビューフォーム　2019年5月 (第4版).
– reference: 1) 図解で学ぶDDS―薬物治療の最適化を目指す先端創薬技術. 橋本　充 監, 高倉喜信 編, じほう; 2010 Section 1, 2.
– reference: 3) レミカット®カプセル　インタビューフォーム　2019年4月 (第8版).
– reference: 4) インタール®細粒　インタビューフォーム　2012年10月 (第5版).
– reference: 5) インタール®エアロゾル　インタビューフォーム　2012年10月 (第9版).
– reference: 6) インタール®点鼻液　インタビューフォーム　2012年10月 (第7版).
– reference: 7) フルナーゼ®点鼻液　インタビューフォーム　2019年4月 (第15版).
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SubjectTerms Drug Delivery System (DDS)
Emedastine fumarate
Fluticasone propionate
Pharmacokinetics
Sodium cromoglycate
エメダスチンフマル酸塩
クロモグリク酸ナトリウム
ドラッグデリバリーシステム
フルチカゾンプロピオン酸エステル
薬物動態
Title DDS Formulations Used in the Otolaryngology Field: Characteristics of Pharmacokinetics and Side Effects
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https://cir.nii.ac.jp/crid/1391975276380108288
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