A Case of Elective Surgery for Acute Appendicitis that Occurred in the Bone Marrow Inhabitation Stage of Acute Myelogenous Leukemia
A 36-year-old woman was diagnosed as having acute myelogenous leukemia and started anti-leukemic treatment. The patient complained of right lower quadrant pain and a high fever on the 14th day after initiation of the regimen. Abdominal computed tomography (CT) revealed a swollen appendix and the pat...
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| Published in | Nihon Fukubu Kyukyu Igakkai Zasshi (Journal of Abdominal Emergency Medicine) Vol. 38; no. 4; pp. 707 - 710 |
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| Main Authors | , |
| Format | Journal Article |
| Language | Japanese |
| Published |
Japanese Society for Abdominal Emergency Medicine
31.05.2018
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| Online Access | Get full text |
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| Abstract | A 36-year-old woman was diagnosed as having acute myelogenous leukemia and started anti-leukemic treatment. The patient complained of right lower quadrant pain and a high fever on the 14th day after initiation of the regimen. Abdominal computed tomography (CT) revealed a swollen appendix and the patient was diagnosed as having acute appendicitis, however the laboratory data showed pancytopenia. Therefore, we preferred conservative therapy to surgery. Starting on the 14th days after conservative therapy, the pancytopenia improved, so we performed a laparoscopic appendectomy. The patient was discharged on the 7th day after the surgery without complication. We report our experience with a review of the pertinent literature. |
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| AbstractList | A 36-year-old woman was diagnosed as having acute myelogenous leukemia and started anti-leukemic treatment. The patient complained of right lower quadrant pain and a high fever on the 14th day after initiation of the regimen. Abdominal computed tomography (CT) revealed a swollen appendix and the patient was diagnosed as having acute appendicitis, however the laboratory data showed pancytopenia. Therefore, we preferred conservative therapy to surgery. Starting on the 14th days after conservative therapy, the pancytopenia improved, so we performed a laparoscopic appendectomy. The patient was discharged on the 7th day after the surgery without complication. We report our experience with a review of the pertinent literature. |
| Author | Noguchi, Takuya Kawano, Yuichiro |
| Author_xml | – sequence: 1 fullname: Kawano, Yuichiro organization: Department of Gastroenterological Surgery, Tsurumi Hospital – sequence: 2 fullname: Noguchi, Takuya organization: Department of Gastroenterological Surgery, Tsurumi Hospital |
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| Copyright | 2018, Japanese Society for Abdominal Emargency Medicine |
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| DOI | 10.11231/jaem.38.707 |
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| References | 3) Wallace J, Schwaitzberg S, Miller K: Sometimes it really is appendicitis: case of CML patient with acute appendicitis. Ann Hematol 1998; 77: 61-64. 2) Chirletti P, Barilliari P, Sammartino P, et al: The surgical choice in neutrophenic patients with hematological disorders and acute abdominal complications. Leuk Lymphoma 1993; 9: 237-241. 5) Hunter TB, Bjelland JC: Gastrointestinal complications of leukemia and its treatment. AJR Am J Roentgenol 1984; 142: 513-518. 7) Kuffer F, Fortner J, Murphy ML: Surgical complications in children undergoing cancer therapy. Ann Surg 1968; 167: 215-219. 11) 田中浩明，角田卓也，小西寿一郎，ほか：急性骨髄性白血病治療中の骨髄抑制期に発症し上行結腸と瘻孔を形成した虫垂炎の1例．日臨外会誌2007；68：1179-1182. 4) Skibber JM, Matter GJ, Pizzo PA, et al: Right lower quadrant pain in young patients with leukemia. A surgical perspective. Ann Surg 1987; 206: 711-716. 1) 中村 徹，上田孝典，福島俊洋：抗白血病剤の作用機序と投与理念．医のあゆみ1994；170：859-864. 10) 梶原良介，後藤裕明，横須賀とも子，ほか：化学療法後の骨髄抑制中に急性虫垂炎を発症した急性白血病の3例．臨血2007；48：223-228. 8) 西尾康平，渋谷雅常，永原 央，ほか：急性骨髄性白血病の骨髄抑制期に発症した急性虫垂炎の1例．日臨外会誌2014；75：1616-1620. 13) 金森 豊：外科的管理や治療を要する免疫不全患児．小児外科2007；39：1425-1429. 6) Katz JA, Wagner ML, Gresik MV, et al: Typhlitis: an 18-year experience and postmortem review. Cancer 1990; 65: 1041-1047. 14) 小林照忠，中川国利，月館久勝，ほか：急性虫垂炎に対する腹腔鏡下手術と開腹手術の比較検討．日外科系連会誌2013；38：197-202. 9) 三宅邦智，瀬下明良，松岡あづさ，ほか：急性混合性白血病の化学療法による骨髄抑制期に発症した急性虫垂炎の1例．日臨外会誌2011；72：103-106. 12) 落合二葉，黒沢秀光，鹿嶋広久，ほか：寛解導入療法による骨髄抑制の時期に急性虫垂炎を合併した急性非リンパ性白血病の2症例．小児臨1991；44：1230-1234. |
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| Title | A Case of Elective Surgery for Acute Appendicitis that Occurred in the Bone Marrow Inhabitation Stage of Acute Myelogenous Leukemia |
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