A clinical study on monoclonal plasmacyte cell tumor (extramedullary plasmacytoma) arising in the head and neck region

• Published in: jibi to rinsho Vol. 61; no. 6; pp. 223 - 229
• Main Authors: YOSHIFUKU, Kousuke, MATSUZAKI, Tsutomu, NISHIMOTO, Kengo, NOMOTO, Mitsuharu, UMAKOSHI, Mizuo
• Format: Journal Article
• Language: Japanese
• Published: JIBI TO RINSHO KAI 20.11.2015; 耳鼻と臨床会
• Subjects: 単クローン性形質細胞性腫瘍; 手術治療; 放射線治療; 頭頸部領域
• ISSN: 0447-7227; 2185-1034
• DOI: 10.11334/jibi.61.6_223

Monoclonal plasmacyte cell tumor (MPCT ; also known as extramedullary plasmacytoma) is a rare disease, which arises most commonly in the head and neck. Many reports have suggested the head and neck region to be most common site for MPCT, thus head and neck surgeons should be aware of its clinical manifestations. We recently treated 4 patients, 3 with an MPCT in the nasosinudal legion and 1 patient with an MPCT in the larynx and mesopharyngeal regions, and investigated the diagnostic utility of the clinical features and examinations, in addition to the efficacy of these treatments. All of the patients presented symptoms that involved the local regions of the tumor, but there were no specific findings related to the clinical features or imaging that allowed for the differential diagnosis of MPCT. All cases were diagnosed by a pathological examination. The MPCT patients underwent combination treatments involving surgery and irradiation, and we were able to select an effective method for achieving the local control of MPCT.