Dietary intervention of prebiotic partially hydrolyzed guar gum improves skin viscoelasticity, stratum corneum hydration, and ‍reduction of trans-epidermal water loss: a ‍randomized, double-blind, and placebo-controlled clinical study in healthy humans

• Published in: Journal of Clinical Biochemistry and Nutrition Vol. 76; no. 1; pp. 96 - 115
• Main Authors: Kapoor, Mahendra P., Abe, Aya, Morishima, So, Nakajima, Atsushi, Ozeki, Makoto, Sato, Norio
• Format: Journal Article
• Language: English
• Published: Japan SOCIETY FOR FREE RADICAL RESEARCH JAPAN 01.01.2025; Japan Science and Technology Agency; the Society for Free Radical Research Japan
• Subjects: Clinical trials; Dietary fiber; epidermis; Females; Guar gum; Hydration; Intestinal microflora; Males; Microbiomes; Original; Parameters; Placebos; Prebiotics; Skin diseases; Stratum corneum; trans-epidermal water loss; Viscoelasticity; Water loss; Winter; stratum corneum; trans-epidermal water loss; hydration; viscoelasticity; epidermis

Dietary fiber-rich diets are gaining popularity as an alternative therapy for skin health. Plant-based prebiotic partially hydrolyzed guar gum (PHGG) dietary fiber promotes gastrointestinal health, which is imperative for skin health through the gut microbiome. In this randomized, double-blind, and...