Consistent Alterations of Circulating Matrix Metalloproteinases Levels in Untreated Hypertensives and in Spontaneously Hypertensive Rats: A Relevant Pharmacological Target - Fontana, Vanessa; Silva, Pamela S.; Belo, Vanessa A.; Antonio, Raquel C.; Ceron, Carla S.; Biagi, Celso; Gerlach, Raquel F.; Tanus‐Santos, Jose E. (Basic & clinical pharmacology & toxicology, 2011)
Keywords: Adult; Animal models; Animals; Antihypertensives; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Drugs; Enzyme-linked immunosorbent assay; Gelatin; Gelatinase A; Gelatinase B; Humans; Hypertension; Hypertension - enzymology; Male; Matrix metalloproteinase; Matrix Metalloproteinase 2 - blood; Matrix Metalloproteinase 8 - blood; Matrix Metalloproteinase 9 - blood; Matrix Metalloproteinases - blood; Medical sciences; Middle Aged; Neutrophil collagenase; Pharmacology. Drug treatments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tissue inhibitor of metalloproteinase 1; Tissue inhibitor of metalloproteinase 2; Tissue inhibitor of metalloproteinases; Hypertension; Targeting; Rat; Enzyme; Rodentia; Cardiovascular disease; Metalloendopeptidases; Peptidases; Vertebrata; Target; Mammalia; Animal; Hydrolases