In Vitro Assessment of 36 CYP2C9 Allelic Isoforms Found in the Chinese Population on the Metabolism of Glimepiride - Dai, Da‐Peng; Wang, Shuang‐Hu; Geng, Pei‐Wu; Hu, Guo‐Xin; Cai, Jian‐Ping (Basic & clinical pharmacology & toxicology, 2014)
Keywords: Alleles; Aryl Hydrocarbon Hydroxylases - genetics; Aryl Hydrocarbon Hydroxylases - metabolism; Asian Continental Ancestry Group - genetics; Biological and medical sciences; China; Cytochrome P-450 CYP2C9; General and cellular metabolism. Vitamins; Genotype; Humans; Hydroxylation; Hypoglycemic Agents - pharmacology; Medical sciences; Microsomes - metabolism; Mutation; Pharmacology. Drug treatments; Polymorphism, Genetic; Protein Isoforms - genetics; Recombinant Proteins - genetics; Recombinant Proteins - metabolism; Sulfonylurea Compounds - pharmacology; Tandem Mass Spectrometry; China; Human; Evaluation; Glimepiride; Molecular form; Enzyme; Isozyme; Cytochrome P450; Metabolism; In vitro; Hypoglycemic agent; Sulfonamides; Sulfonylureas; Chinese; Pharmacokinetics; CYP2C9 gene