Protein arginine methyltransferase 5 is a potential oncoprotein that upregulates G1 cyclins/cyclin‐dependent kinases and the phosphoinositide 3‐kinase/AKT signaling cascade - Wei, Tong‐You W.; Juan, Chi‐Chang; Hisa, Jiun‐Yi; Su, Li‐Jen; Lee, Yuan‐Chii G.; Chou, Hsiang‐Yun; Chen, Jo‐Mei M.; Wu, Yu‐Chung; Chiu, Shao‐Chih; Hsu, Chung‐Ping; Liu, Kuo‐Lin; Yu, Chang‐Tze R. (Cancer science, 2012)
Keywords: 1-Phosphatidylinositol 3-kinase; AKT protein; Animals; c-Jun amino-terminal kinase; c-Jun protein; Cell adhesion; Cell cycle; Cell density; Cell Line, Tumor; Cell proliferation; Cell Transformation, Neoplastic - genetics; Cell Transformation, Neoplastic - metabolism; cyclin D1; Cyclin-dependent kinase; Cyclin-Dependent Kinases - metabolism; Cyclins; Data processing; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Lung cancer; Lung Neoplasms - genetics; Lung Neoplasms - metabolism; Mice; Mice, Nude; Oncogene Proteins - genetics; Oncogene Proteins - metabolism; Original; Phosphatidylinositol 3-Kinases - metabolism; phosphoinositides; protein arginine methyltransferase; Protein-Arginine N-Methyltransferases - genetics; Protein-Arginine N-Methyltransferases - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Retinoblastoma protein; Signal Transduction; Statistical analysis; Transcription factors; Tumor cell lines; Tumorigenesis; Western blotting