The Methyltransferase-Like Domain of Chikungunya Virus nsP2 Inhibits the Interferon Response by Promoting the Nuclear Export of STAT1 - Göertz, Giel P; McNally, Kristin L; Robertson, Shelly J; Best, Sonja M; Pijlman, Gorben P; Fros, Jelke J (Journal of virology, 2018)
Keywords: Cell Line; Chikungunya virus - enzymology; Chikungunya virus - genetics; Chikungunya virus - physiology; Computer Simulation; Cysteine Endopeptidases - genetics; Cysteine Endopeptidases - metabolism; HEK293 Cells; Host-Pathogen Interactions - genetics; Host-Pathogen Interactions - immunology; Humans; Immunity, Innate; Immunoprecipitation; Interferon Type I - antagonists & inhibitors; Interferon Type I - genetics; Interferon Type I - immunology; Methyltransferases - metabolism; Mutation; Signal Transduction - genetics; Signal Transduction - immunology; STAT1 Transcription Factor - genetics; Virus Replication; Virus-Cell Interactions; nonstructural protein 2; STAT signaling; interferons; alphavirus; innate immunity; chikungunya