The Role of Autophagy in Nanoparticles-Induced Toxicity and Its Related Cellular and Molecular Mechanisms

• Published in: Advances in experimental medicine and biology Vol. 1048; p. 71
• Main Authors: Li, Yubin, Ju, Dianwen
• Format: Journal Article
• Language: English
• Published: United States 01.01.2018
• Subjects: Animals; Apoptosis - drug effects; Autophagy - drug effects; Drug Delivery Systems - adverse effects; Humans; Nanoparticles - adverse effects; Necrosis; Oxidative Stress - drug effects; Nanoparticles; Oxidative stress; Mitophagy; Nanotoxicology; Autophagy

In the past decades, nanoparticles have been widely used in industry and pharmaceutical fields for drug delivery, anti-pathogen, and diagnostic imaging purposes because of their unique physicochemical characteristics such as special ultrastructure, dispersity, and effective cellular uptake propertie...