けいれん発作にともなう急性期MRI 異常信号
要旨：けいれん発作，とくにけいれん重積発作にともない，皮質や皮質下領域にMRI で信号異常を認めることがある．海馬を含む大脳皮質や，皮質下病変として視床，脳梁，また小脳など多岐にわたる部位での信号異常が報告されている．これらのけいれん発作にともなうMRI 異常信号は，異常興奮による脳局所の血流増加や代謝亢進を反映していると考えられる．最近では，臨床の場で脳血管障害や脳腫瘍などの他疾患との鑑別が問題になるケースにも出合うようになった．本稿では，けいれん発作にともなうMRI 異常信号について，臨床的，画像的，生物学的，病理学的観点から概説する．...
Saved in:
| Published in | 脳卒中 Vol. 36; no. 4; pp. 247 - 254 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
一般社団法人 日本脳卒中学会
2014
日本脳卒中学会 |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0912-0726 1883-1923 |
| DOI | 10.3995/jstroke.36.247 |
Cover
| Abstract | 要旨：けいれん発作，とくにけいれん重積発作にともない，皮質や皮質下領域にMRI で信号異常を認めることがある．海馬を含む大脳皮質や，皮質下病変として視床，脳梁，また小脳など多岐にわたる部位での信号異常が報告されている．これらのけいれん発作にともなうMRI 異常信号は，異常興奮による脳局所の血流増加や代謝亢進を反映していると考えられる．最近では，臨床の場で脳血管障害や脳腫瘍などの他疾患との鑑別が問題になるケースにも出合うようになった．本稿では，けいれん発作にともなうMRI 異常信号について，臨床的，画像的，生物学的，病理学的観点から概説する． |
|---|---|
| AbstractList | 要旨：けいれん発作，とくにけいれん重積発作にともない，皮質や皮質下領域にMRI で信号異常を認めることがある．海馬を含む大脳皮質や，皮質下病変として視床，脳梁，また小脳など多岐にわたる部位での信号異常が報告されている．これらのけいれん発作にともなうMRI 異常信号は，異常興奮による脳局所の血流増加や代謝亢進を反映していると考えられる．最近では，臨床の場で脳血管障害や脳腫瘍などの他疾患との鑑別が問題になるケースにも出合うようになった．本稿では，けいれん発作にともなうMRI 異常信号について，臨床的，画像的，生物学的，病理学的観点から概説する． 「要旨」:けいれん発作, とくにけいれん重積発作にともない, 皮質や皮質下領域にMRIで信号異常を認めることがある. 海馬を含む大脳皮質や, 皮質下病変として視床, 脳梁, また小脳など多岐にわたる部位での信号異常が報告されている. これらのけいれん発作にともなうMRI異常信号は, 異常興奮による脳局所の血流増加や代謝亢進を反映していると考えられる. 最近では, 臨床の場で脳血管障害や脳腫瘍などの他疾患との鑑別が問題になるケースにも出合うようになった. 本稿では, けいれん発作にともなうMRI異常信号について, 臨床的, 画像的, 生物学的, 病理学的観点から概説する. 「はじめに」 けいれん発作, とくにけいれん重積発作にともない, 皮質や皮質下領域にMRIで信号異常を認めることがある. 海馬を含む大脳皮質や, 皮質下病変として視床, 脳梁, また小脳など多岐にわたる部位での信号異常が報告されている. これらのけいれん発作にともなうMRI異常信号は, 異常興奮による脳局所の血流増加や代謝亢進を反映していると考えられる. |
| Author | 棚橋, 紀夫 大江, 康子 内野, 晃 林, 健 |
| Author_xml | – sequence: 1 fullname: 棚橋, 紀夫 organization: 埼玉医科大学国際医療センター神経内科 – sequence: 1 fullname: 内野, 晃 organization: 同画像診断科 – sequence: 1 fullname: 大江, 康子 organization: 埼玉医科大学国際医療センター神経内科 – sequence: 1 fullname: 林, 健 organization: 埼玉医科大学国際医療センター神経内科 |
| BookMark | eNo1kM9Kw0AQxhepYK29evYFUje7m2zirRSthYogel422Y1NTBNJ68FbE8STICIehIJ4EEUv3iyC-DDbP6_h1uplPphhft_MtwpKSZpIANZNWMOua21GvX6WnsgatmuI0CVQNh0HG6aLcAmUoWsiA1Jkr4Bqrxd60HKIi13bLYMtld-o_EIVV6q4nd1_jr-GKn9T-YsqCpW_qvxyOniaDp6nw4e9g9bG7O59MhqNvx8n1x9rYDngcU9W_7QCjna2Dxu7Rnu_2WrU20aETQwNLGRAsB14WF8ReAQKIRCEAedSEOJQFFDd4dKxqaBEUEtg4fiCcCqIpB7BFdBccLtShD6P0yQOE8mi9CxLtC8THfz7PEPQJAxCbMO5mAzqJHSxCELa2kSaVF-QdFr8WLLTLOzy7JzxrB_6sUYuQmTYZmRe5vv_M7_DMxZx_ANPHIDq |
| ContentType | Journal Article |
| Copyright | 2014 日本脳卒中学会 |
| Copyright_xml | – notice: 2014 日本脳卒中学会 |
| CorporateAuthor | 埼玉医科大学国際医療センター神経内科 埼玉医科大学国際医療センター画像診断科 |
| CorporateAuthor_xml | – name: 埼玉医科大学国際医療センター神経内科 – name: 埼玉医科大学国際医療センター画像診断科 |
| DOI | 10.3995/jstroke.36.247 |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1883-1923 |
| EndPage | 254 |
| ExternalDocumentID | dh3strok_2014_003604_001_0247_02542291212 article_jstroke_36_4_36_247_article_char_ja |
| GroupedDBID | 123 2WC ALMA_UNASSIGNED_HOLDINGS EIHBH GROUPED_DOAJ JSF KQ8 MOJWN RJT |
| ID | FETCH-LOGICAL-j3130-3def436fb3912fb40ddd200faaed44872f7dddae867d74d75d3d8cd4a7d4e7b43 |
| ISSN | 0912-0726 |
| IngestDate | Thu Jul 10 16:14:14 EDT 2025 Wed Sep 03 06:00:28 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 4 |
| Language | Japanese |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-j3130-3def436fb3912fb40ddd200faaed44872f7dddae867d74d75d3d8cd4a7d4e7b43 |
| OpenAccessLink | https://www.jstage.jst.go.jp/article/jstroke/36/4/36_247/_article/-char/ja |
| PageCount | 8 |
| ParticipantIDs | medicalonline_journals_dh3strok_2014_003604_001_0247_02542291212 jstage_primary_article_jstroke_36_4_36_247_article_char_ja |
| PublicationCentury | 2000 |
| PublicationDate | 20140000 |
| PublicationDateYYYYMMDD | 2014-01-01 |
| PublicationDate_xml | – year: 2014 text: 20140000 |
| PublicationDecade | 2010 |
| PublicationTitle | 脳卒中 |
| PublicationTitleAlternate | 脳卒中 |
| PublicationYear | 2014 |
| Publisher | 一般社団法人 日本脳卒中学会 日本脳卒中学会 |
| Publisher_xml | – name: 一般社団法人 日本脳卒中学会 – name: 日本脳卒中学会 |
| References | 25) Jackson GD, Chambers BR, Berkovic SF: Hippocampal sclerosis: development in adult life. Dev Neurosci 21: 207–214, 1999 4) Szabo K, Poepel A, Pohlmann-Eden B, et al: Diffusion-weighted and perfusion MRI demonstrates parenchymal changes in complex partial status epilepticus. Brain 128: 1369–1376, 2005 50) Runge U, Kirsch G, Petersen B, et al: Ictal and interictal ECDSPECT for focus localization in epilepsy. Acta Neurol Scand 96: 271–276, 1997 38) Stübgen JP: Crossed cerebellar diaschisis related to recurrent focal seizures. Epilepsia 36: 316–318, 1995 23) Tien RD, Ashdown BC: Crossed cerebellar diaschisis and crossed cerebellar atrophy: correlation of MRI findings, clinical symptoms and supratentorial diseases in 26 patients. Am J Roentgenology 58: 1155–1159, 1992 19) Righini A, Pierpaoli C, Alger JR, et al: Brain parenchyma apparent diffusion coefficient alterations associated with experimental complex partial status epilepticus. Magn Reson Imaging 12: 865–871, 1994 51) Thom M, Sisodiya S, Najm I. Neuropathology of epilepsy. In Love S, et al (eds): Greenfield’s Neuropathology, 8th ed, London, Hodder Arnold, 2008, pp 833–887 48) Marks DA, Katz A, Hoffer P, et al: Localization of extratemporal epileptic foci during ictal single photon emission computed tomography. Ann Neurol 31: 250–255, 1992 36) Gröppel G, Gallmetzer P, Prayer D, et al: Focal lesions in the splenium of the corpus callosum in patients with epilepsy. Epilepsia 50: 1354–1360, 2009 1) Cianfoni A, Caulo M, Cerase A, et al: Seizure-induced brain lesions: a wide spectrum of variably reversible MRI abnormalities. Eur J Radiol 82: 1964–1972, 2013 35) Tada H, Takanashi J, Barkovich AJ, et al: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology 63: 1854–1858, 2004 30) Cox JE, Mathews VP, Santos CC, et al: Seizure-induced transient hippocampal abnormalities on MR: correlation with positron emission tomography and electroencephalography. AJNR Am J Neuroradiol 16: 1736–1738, 1995 55) Dolinak D, Smith C, Graham DI: Global hypoxia per se is an unusual cause of axonal injury. Acta Neuropathol 100: 553–560, 2000 41) Ohe Y, Hayashi T, Deguchi I, et al: A case of non-convulsive status epilepticus with crossed cerebellar diaschisis—temporal change of MRI and SPECT findings—. J Stroke Cerebrovasc Dis 2013 Jul 30. doi:pii: S1052-3057(13)00084-0. 10.1016/j.jstrokecerebrovasdis.2013.03.015. 10) Wieshmann UC, Clark CA, Symms MR, et al: Water diffusion in the human hippocampus in epilepsy. Magn Reson Imaging 17: 29–36, 1999 22) Seidenberg M, Hermann B, Pulsipher D, et al: Thalamic atrophy and cognition in unilateral temporal lobe epilepsy. J Int Neuropsychol Soc 14: 384–393, 2008 14) Maeda M, Shiroyama T, Tsukahara H, et al: Transient splenial lesion of the corpus callosum associated with antiepileptic drugs: evaluation by diffusion-weighted MR imaging. Eur Radiol 13: 1902–1906, 2003 52) Fountain BN. Cellular damage and the neuropathology of status epilepticus. In Drislane WF (eds): Status epilepticus—A clinical perspective—. New Jersey, Humana press, 2010, pp 181–193 49) Rowe CC, Berkovic SF, Sia ST, et al: Localization of epileptic foci with postictal single photon emission computed tomography. Ann Neurol 26: 660–668, 1989 43) Hogan RE, Kaiboriboon K, Bertrand ME, et al: Composite SISCOM perfusion patterns in right and left temporal seizures. Arch Neurol 63: 1419–1426, 2006 40) Al-Jafen BN, Alanazy MH, Scott JN, et al: Magnetic resonance imaging of crossed cerebellar diaschisis and bright pulvinar in status epilepticus. Neurosciences (Riyadh) 17: 259–261, 2012 9) Ohe Y, Hayashi T, Deguchi I, et al: MRI abnormality of the pulvinar in patients with status epilepticus. J Neuroradiol pii: S0150-9861(13)00087-4, 2014 12) Kim SS, Chang KH, Kim ST, et al: Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity? AJNR Am J Neuroradiol 20: 125–129, 1999 27) Nohria V, Lee N, Tien RD, et al: Magnetic resonance imaging evidence of hippocampal sclerosis in progression: a case report. Epilepsia 35: 1332–1336, 1994 17) Scott RC, King MD, Gadian DG, et al: Prolonged febrile seizures are associated with hippocampal vasogenic edema and developmental changes. Epilepsia 47: 1493–1498, 2006 54) Auvin S, Devisme L, Maurage CA, et al: Neuropathological and MRI findings in an acute presentation of hemiconvulsion-hemiplegia: a report with pathophysiological implications. Seizure 16: 371–376, 2007 44) 大槻泰助， 開道貴信， 高橋章夫ら： 発作時SPECT とニューロネットワーク．臨床脳波51: 406–409, 2009 31) Shipp S: The functional logic of cortico-pulvinar connections. Philos Trans R Soc Lond B Biol Sci 358: 1605–1624, 2003 5) Lansberg MG, O’Brien MW, Norbash AM, et al: MRI abnormalities associated with partial status epilepticus. Neurology 52: 1021–1027, 1999 16) Cole AJ: Status epilepticus and periictal imaging. Epilepsia 45 Suppl 4: 72–77, 2004 45) Won JH, Lee JD, Chung TS, et al: Increased contralateral cerebellar uptake of technetium-99m-HMPAO on ictal brain SPECT. J Nucl Med 37: 426–429, 1996 8) Katramados AM, Burdette D, Patel SC, et al: Periictal diffusion abnormalities of the thalamus in partial status epilepticus. Epilepsia 50: 265–275, 2009 11) Avoli M: A brief history on the oscillating roles of thalamus and cortex in absence seizures. Epilepsia 53: 779–789, 2012 2) Milligan TA, Zamani A, Bromfield E: Frequency and patterns of MRI abnormalities due to status epilepticus. Seizure 18: 104–108, 2009 7) Toledo M, Munuera J, Sueiras M, et al: MRI findings in aphasic status epilepticus. Epilepsia 49: 1465–1469, 2008 21) Tschampa HJ, Greschus S, Sassen R, et al: Thalamus lesions in chronic and acute seizure disorders. Neuroradiology 53: 245–254, 2011 28) Farina L, Bergqvist C, Zimmerman RA, et al: Acute diffusion abnormalities in the hippocampus of children with new-onset seizures: the development of mesial temporal sclerosis. Neuroradiology 46: 251–257, 2004 15) Nelles M, Bien CG, Kurthen M, et al: Transient splenium lesions in presurgical epilepsy patients: incidence and pathogenesis. Neuroradiology 48: 443–448, 2006 24) Briellmann RS, Newton MR, Wellard RM, et al: Hippocampal sclerosis following brief generalized seizures in adulthood. Neurology 57: 315–317, 2001 34) Ogura H, Takaoka M, Kishi M, et al: Reversible MR findings of hemolytic uremic syndrome with mild encephalopathy. AJNR Am J Neuroradiol 19: 1144–1145, 1998 42) Hope O, Blumenfeld H. Cellular physiology of status epilepticus. In Drislane WF (ed): Status epilepticus—A clinical perspective—, New Jersey, Humana press, 2010, pp 159–180 13) Mirsattari SM, Lee DH, Jones MW, et al: Transient lesion in the splenium of the corpus callosum in an epileptic patient. Neurology 60: 1838–1841, 2003 29) Chevret L, Husson B, Nguefack S, et al: Prolonged refractory status epilepticus with early and persistent restricted hippocampal signal MRI abnormality. J Neurol 255: 112–116, 2008 46) Umemura A, Suzuka T: Crossed cerebellar hyperperfusion in symptomatic epilepsy—two case reports. Neurol Med Chir (Tokyo) 40: 65–68, 2000 20) Nakasu Y, Nakasu S, Morikawa S, et al: Diffusion-weighted MR in experimental sustained seizures elicited with kainic acid. AJNR Am J Neuroradiol 16: 1185–1192, 1995 56) Mori F, Nishie M, Houzen H, et al: Hypoglycemic encephalopathy with extensive lesions in the cerebral white matter. Neuropathology 26: 147–152, 2006 18) Hong KS, Cho YJ, Lee SK, et al: Diffusion changes suggesting predominant vasogenic oedema during partial status epilepticus. Seizure 13: 317–321, 2004 26) VanLandingham KE, Heinz ER, Cavazos JE, et al: Magnetic resonance imaging evidence of hippocampal injury after prolonged focal febrile convulsions. Ann Neurol 43: 413–426, 1998 37) Thajeb P, Shih BF, Wu MC: Crossed cerebellar diaschisis in herpes simplex encephalitis. Eur J Radiol 38: 55–58, 2001 3) Chatzikonstantinou A, Gass A, Förster A, et al: Features of acute DWI abnormalities related to status epilepticus. Epilepsy Res 97: 45–51, 2011 32) Takanashi J, Barkovich AJ, Yamaguchi K, et al: Influenza-associated encephalitis/encephalopathy with a reversible lesion in the splenium of the corpus callosum: a case report and literature review. AJNR Am J Neuroradiol 25: 798–802, 2004 33) Kobata R, Tsukahara H, Nakai A, et al: Transient MR signal changes in the splenium of the corpus callosum in rotavirus encephalopathy: value of diffusion-weighted imaging. J Comput Assist Tomogr 26: 825–828, 2002 6) Parmar H, Lim SH, Tan NC, et al: Acute symptomatic seizures and hippocampus damage: DWI and MRS findings. Neurology 66: 1732–1735, 2006 47) Harvey AS, Hopkins IJ, Bowe JM, et al: Frontal lobe epilepsy: clinical seizure characteristics and localization with ictal 99mTc-HMPAO SPECT. Neurology 43: 1966–1980, 1993 53) Mori F, Tanji K, Miki Y, et al: Status epilepticus associated with extensive axonal swelling in the unilateral cerebral cortex and hippocampus. Neuropathol Appl Neurobiol 38: 387–390, 2012 39) Nagasaka T, Shindo K, Hiraide M, et al: Ipsilateral thalamic MRI abnormality in an epilepsy patient. Neurology 58: 641–644, 2002 |
| References_xml | – reference: 24) Briellmann RS, Newton MR, Wellard RM, et al: Hippocampal sclerosis following brief generalized seizures in adulthood. Neurology 57: 315–317, 2001 – reference: 43) Hogan RE, Kaiboriboon K, Bertrand ME, et al: Composite SISCOM perfusion patterns in right and left temporal seizures. Arch Neurol 63: 1419–1426, 2006 – reference: 36) Gröppel G, Gallmetzer P, Prayer D, et al: Focal lesions in the splenium of the corpus callosum in patients with epilepsy. Epilepsia 50: 1354–1360, 2009 – reference: 21) Tschampa HJ, Greschus S, Sassen R, et al: Thalamus lesions in chronic and acute seizure disorders. Neuroradiology 53: 245–254, 2011 – reference: 56) Mori F, Nishie M, Houzen H, et al: Hypoglycemic encephalopathy with extensive lesions in the cerebral white matter. Neuropathology 26: 147–152, 2006 – reference: 9) Ohe Y, Hayashi T, Deguchi I, et al: MRI abnormality of the pulvinar in patients with status epilepticus. J Neuroradiol pii: S0150-9861(13)00087-4, 2014 – reference: 48) Marks DA, Katz A, Hoffer P, et al: Localization of extratemporal epileptic foci during ictal single photon emission computed tomography. Ann Neurol 31: 250–255, 1992 – reference: 35) Tada H, Takanashi J, Barkovich AJ, et al: Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology 63: 1854–1858, 2004 – reference: 14) Maeda M, Shiroyama T, Tsukahara H, et al: Transient splenial lesion of the corpus callosum associated with antiepileptic drugs: evaluation by diffusion-weighted MR imaging. Eur Radiol 13: 1902–1906, 2003 – reference: 26) VanLandingham KE, Heinz ER, Cavazos JE, et al: Magnetic resonance imaging evidence of hippocampal injury after prolonged focal febrile convulsions. Ann Neurol 43: 413–426, 1998 – reference: 2) Milligan TA, Zamani A, Bromfield E: Frequency and patterns of MRI abnormalities due to status epilepticus. Seizure 18: 104–108, 2009 – reference: 10) Wieshmann UC, Clark CA, Symms MR, et al: Water diffusion in the human hippocampus in epilepsy. Magn Reson Imaging 17: 29–36, 1999 – reference: 46) Umemura A, Suzuka T: Crossed cerebellar hyperperfusion in symptomatic epilepsy—two case reports. Neurol Med Chir (Tokyo) 40: 65–68, 2000 – reference: 31) Shipp S: The functional logic of cortico-pulvinar connections. Philos Trans R Soc Lond B Biol Sci 358: 1605–1624, 2003 – reference: 1) Cianfoni A, Caulo M, Cerase A, et al: Seizure-induced brain lesions: a wide spectrum of variably reversible MRI abnormalities. Eur J Radiol 82: 1964–1972, 2013 – reference: 7) Toledo M, Munuera J, Sueiras M, et al: MRI findings in aphasic status epilepticus. Epilepsia 49: 1465–1469, 2008 – reference: 34) Ogura H, Takaoka M, Kishi M, et al: Reversible MR findings of hemolytic uremic syndrome with mild encephalopathy. AJNR Am J Neuroradiol 19: 1144–1145, 1998 – reference: 4) Szabo K, Poepel A, Pohlmann-Eden B, et al: Diffusion-weighted and perfusion MRI demonstrates parenchymal changes in complex partial status epilepticus. Brain 128: 1369–1376, 2005 – reference: 13) Mirsattari SM, Lee DH, Jones MW, et al: Transient lesion in the splenium of the corpus callosum in an epileptic patient. Neurology 60: 1838–1841, 2003 – reference: 40) Al-Jafen BN, Alanazy MH, Scott JN, et al: Magnetic resonance imaging of crossed cerebellar diaschisis and bright pulvinar in status epilepticus. Neurosciences (Riyadh) 17: 259–261, 2012 – reference: 19) Righini A, Pierpaoli C, Alger JR, et al: Brain parenchyma apparent diffusion coefficient alterations associated with experimental complex partial status epilepticus. Magn Reson Imaging 12: 865–871, 1994 – reference: 53) Mori F, Tanji K, Miki Y, et al: Status epilepticus associated with extensive axonal swelling in the unilateral cerebral cortex and hippocampus. Neuropathol Appl Neurobiol 38: 387–390, 2012 – reference: 42) Hope O, Blumenfeld H. Cellular physiology of status epilepticus. In Drislane WF (ed): Status epilepticus—A clinical perspective—, New Jersey, Humana press, 2010, pp 159–180 – reference: 38) Stübgen JP: Crossed cerebellar diaschisis related to recurrent focal seizures. Epilepsia 36: 316–318, 1995 – reference: 32) Takanashi J, Barkovich AJ, Yamaguchi K, et al: Influenza-associated encephalitis/encephalopathy with a reversible lesion in the splenium of the corpus callosum: a case report and literature review. AJNR Am J Neuroradiol 25: 798–802, 2004 – reference: 37) Thajeb P, Shih BF, Wu MC: Crossed cerebellar diaschisis in herpes simplex encephalitis. Eur J Radiol 38: 55–58, 2001 – reference: 27) Nohria V, Lee N, Tien RD, et al: Magnetic resonance imaging evidence of hippocampal sclerosis in progression: a case report. Epilepsia 35: 1332–1336, 1994 – reference: 44) 大槻泰助， 開道貴信， 高橋章夫ら： 発作時SPECT とニューロネットワーク．臨床脳波51: 406–409, 2009 – reference: 17) Scott RC, King MD, Gadian DG, et al: Prolonged febrile seizures are associated with hippocampal vasogenic edema and developmental changes. Epilepsia 47: 1493–1498, 2006 – reference: 28) Farina L, Bergqvist C, Zimmerman RA, et al: Acute diffusion abnormalities in the hippocampus of children with new-onset seizures: the development of mesial temporal sclerosis. Neuroradiology 46: 251–257, 2004 – reference: 5) Lansberg MG, O’Brien MW, Norbash AM, et al: MRI abnormalities associated with partial status epilepticus. Neurology 52: 1021–1027, 1999 – reference: 18) Hong KS, Cho YJ, Lee SK, et al: Diffusion changes suggesting predominant vasogenic oedema during partial status epilepticus. Seizure 13: 317–321, 2004 – reference: 22) Seidenberg M, Hermann B, Pulsipher D, et al: Thalamic atrophy and cognition in unilateral temporal lobe epilepsy. J Int Neuropsychol Soc 14: 384–393, 2008 – reference: 11) Avoli M: A brief history on the oscillating roles of thalamus and cortex in absence seizures. Epilepsia 53: 779–789, 2012 – reference: 15) Nelles M, Bien CG, Kurthen M, et al: Transient splenium lesions in presurgical epilepsy patients: incidence and pathogenesis. Neuroradiology 48: 443–448, 2006 – reference: 20) Nakasu Y, Nakasu S, Morikawa S, et al: Diffusion-weighted MR in experimental sustained seizures elicited with kainic acid. AJNR Am J Neuroradiol 16: 1185–1192, 1995 – reference: 8) Katramados AM, Burdette D, Patel SC, et al: Periictal diffusion abnormalities of the thalamus in partial status epilepticus. Epilepsia 50: 265–275, 2009 – reference: 49) Rowe CC, Berkovic SF, Sia ST, et al: Localization of epileptic foci with postictal single photon emission computed tomography. Ann Neurol 26: 660–668, 1989 – reference: 52) Fountain BN. Cellular damage and the neuropathology of status epilepticus. In Drislane WF (eds): Status epilepticus—A clinical perspective—. New Jersey, Humana press, 2010, pp 181–193 – reference: 39) Nagasaka T, Shindo K, Hiraide M, et al: Ipsilateral thalamic MRI abnormality in an epilepsy patient. Neurology 58: 641–644, 2002 – reference: 51) Thom M, Sisodiya S, Najm I. Neuropathology of epilepsy. In Love S, et al (eds): Greenfield’s Neuropathology, 8th ed, London, Hodder Arnold, 2008, pp 833–887 – reference: 41) Ohe Y, Hayashi T, Deguchi I, et al: A case of non-convulsive status epilepticus with crossed cerebellar diaschisis—temporal change of MRI and SPECT findings—. J Stroke Cerebrovasc Dis 2013 Jul 30. doi:pii: S1052-3057(13)00084-0. 10.1016/j.jstrokecerebrovasdis.2013.03.015. – reference: 16) Cole AJ: Status epilepticus and periictal imaging. Epilepsia 45 Suppl 4: 72–77, 2004 – reference: 29) Chevret L, Husson B, Nguefack S, et al: Prolonged refractory status epilepticus with early and persistent restricted hippocampal signal MRI abnormality. J Neurol 255: 112–116, 2008 – reference: 50) Runge U, Kirsch G, Petersen B, et al: Ictal and interictal ECDSPECT for focus localization in epilepsy. Acta Neurol Scand 96: 271–276, 1997 – reference: 6) Parmar H, Lim SH, Tan NC, et al: Acute symptomatic seizures and hippocampus damage: DWI and MRS findings. Neurology 66: 1732–1735, 2006 – reference: 12) Kim SS, Chang KH, Kim ST, et al: Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity? AJNR Am J Neuroradiol 20: 125–129, 1999 – reference: 54) Auvin S, Devisme L, Maurage CA, et al: Neuropathological and MRI findings in an acute presentation of hemiconvulsion-hemiplegia: a report with pathophysiological implications. Seizure 16: 371–376, 2007 – reference: 33) Kobata R, Tsukahara H, Nakai A, et al: Transient MR signal changes in the splenium of the corpus callosum in rotavirus encephalopathy: value of diffusion-weighted imaging. J Comput Assist Tomogr 26: 825–828, 2002 – reference: 55) Dolinak D, Smith C, Graham DI: Global hypoxia per se is an unusual cause of axonal injury. Acta Neuropathol 100: 553–560, 2000 – reference: 25) Jackson GD, Chambers BR, Berkovic SF: Hippocampal sclerosis: development in adult life. Dev Neurosci 21: 207–214, 1999 – reference: 47) Harvey AS, Hopkins IJ, Bowe JM, et al: Frontal lobe epilepsy: clinical seizure characteristics and localization with ictal 99mTc-HMPAO SPECT. Neurology 43: 1966–1980, 1993 – reference: 45) Won JH, Lee JD, Chung TS, et al: Increased contralateral cerebellar uptake of technetium-99m-HMPAO on ictal brain SPECT. J Nucl Med 37: 426–429, 1996 – reference: 23) Tien RD, Ashdown BC: Crossed cerebellar diaschisis and crossed cerebellar atrophy: correlation of MRI findings, clinical symptoms and supratentorial diseases in 26 patients. Am J Roentgenology 58: 1155–1159, 1992 – reference: 3) Chatzikonstantinou A, Gass A, Förster A, et al: Features of acute DWI abnormalities related to status epilepticus. Epilepsy Res 97: 45–51, 2011 – reference: 30) Cox JE, Mathews VP, Santos CC, et al: Seizure-induced transient hippocampal abnormalities on MR: correlation with positron emission tomography and electroencephalography. AJNR Am J Neuroradiol 16: 1736–1738, 1995 |
| SSID | ssib058493969 ssib002671006 ssj0065046 ssib002227608 ssib000940399 ssib059951213 ssib002670963 ssib029852171 ssib002484663 |
| Score | 1.9402794 |
| Snippet | 要旨：けいれん発作，とくにけいれん重積発作にともない，皮質や皮質下領域にMRI で信号異常を認めることがある．海馬を含む大脳皮質や，皮質下病変として視床，脳梁，また小脳など多岐にわたる部位での信号異常が報告されている．これらのけいれん発作にともなうMRI... 「要旨」:けいれん発作, とくにけいれん重積発作にともない, 皮質や皮質下領域にMRIで信号異常を認めることがある. 海馬を含む大脳皮質や, 皮質下病変として視床, 脳梁, また小脳など多岐にわたる部位での信号異常が報告されている. これらのけいれん発作にともなうMRI異常信号は,... |
| SourceID | medicalonline jstage |
| SourceType | Publisher |
| StartPage | 247 |
| SubjectTerms | cerebellum cerebral cortex corpus callosum hippocampus MRI findings seizure thalamus |
| Title | けいれん発作にともなう急性期MRI 異常信号 |
| URI | https://www.jstage.jst.go.jp/article/jstroke/36/4/36_247/_article/-char/ja http://mol.medicalonline.jp/library/journal/download?GoodsID=dh3strok/2014/003604/001&name=0247-0254j |
| Volume | 36 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| ispartofPNX | 脳卒中, 2014, Vol.36(4), pp.247-254 |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3Na9RAFA-1gggifmL9ogfnmJrMTObDk8mapSorKC30FrKbhLJiK-324qm7iCdBRDwIBfEgil68WQTxj0k__g3fm0y6WRGpCsvsYz5e3ptJZn4zmfnFca5RlqpMSOlmHucuZ9J3VaC1ywF7QGcIA3IXF_Q798T8Ir-zFCxNHeGNXUsbg-5c78lvz5X8S6tCHLQrnpL9i5Y9UAoRIEP7QggtDOGh2pjEDJAg0b4VFDcCJaplBc1ILInWJApJzEl0i-iWzRxGtaDqUrSOCWuFgsQCN0OEQS1IFECJbnce3DbKAxJ5JIZQ4Q-v0iahjzGqTSLZhL8kVmhkxEwqGENNfkXGrJCYEnJ7nQicaxvdIWgySVDIG-cFU2KiTQraHTS1gPEKzNZESaJikxdk1iwcMqJDI0BKhN5EHL20NkTNNRF_vBpqdElbKVAXYesPjlmrQ2FioOLC5vIoblmR1Wn-eqSoqFrsE8Gb3X7FGmoRBK1osX8dnPAQMQ5O64O11Yf5HBNzB8UmCL-zZWayJOgZcrcKD__8BOCUTJC9gFKwDj-tfZRK6eNG1rv3G6Bac29ikkmpFA0GJ4qUfWPSNaoVQLjxpAAQqWZaHJRHRjrk_avxDUD66vhbXUMVFSp6d33SNwB1EGG4K048ql47VvQvDQS3cMo5aades2H1HJ12pvrpGedYx24uOevocviyHD4tR8_L0av9N992vm-Vw8_l8GM5GpXDT-Xw2d7m-73ND3tbb-HW33_9ZXd7e-fHu90XX885i-14oTXv2i-LuH0GoM1lWV5wJoouAyeKLveyLIOOpUjTPOMwhaeFhJg0V0JmkmcyyJj5ylcqM57LLmfnnemV1ZX8gjPbK3oB73m-p1IfsF2haSHSAi6iRE9KrWacG1UlJI8r-pjEdheJrayEiYRjgK1bp-GRy6Sfzjg3JyousZ3PenLom-Ti_6u45BzHLNXC42VnerC2kV8BKD7oXjV33k85PK_a |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E3%81%91%E3%81%84%E3%82%8C%E3%82%93%E7%99%BA%E4%BD%9C%E3%81%AB%E3%81%A8%E3%82%82%E3%81%AA%E3%81%86%E6%80%A5%E6%80%A7%E6%9C%9FMRI%E7%95%B0%E5%B8%B8%E4%BF%A1%E5%8F%B7&rft.jtitle=%E8%84%B3%E5%8D%92%E4%B8%AD&rft.au=%E5%A4%A7%E6%B1%9F%E5%BA%B7%E5%AD%90&rft.au=%E6%9E%97%E5%81%A5&rft.au=%E5%86%85%E9%87%8E%E6%99%83&rft.au=%E6%A3%9A%E6%A9%8B%E7%B4%80%E5%A4%AB&rft.date=2014&rft.pub=%E6%97%A5%E6%9C%AC%E8%84%B3%E5%8D%92%E4%B8%AD%E5%AD%A6%E4%BC%9A&rft.issn=0912-0726&rft.volume=36&rft.issue=4&rft.spage=247&rft.epage=254&rft_id=info:doi/10.3995%2Fjstroke.36.247&rft.externalDocID=dh3strok_2014_003604_001_0247_02542291212 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0912-0726&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0912-0726&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0912-0726&client=summon |