Plummer-Vinson症候群に舌癌を伴った1症例
Plummer Vinson症候群は, 鉄欠乏性貧血, 舌炎, 嚥下困難を三主徴とする疾患群で, 近年は栄養状態の改善もあり本邦では比較的稀な疾患である. 症状は動悸, 息切れ, 全身倦怠感などの貧血症状の他に, 輪状後部や頸部食道の粘膜萎縮・Web形成に基づく固形物の嚥下困難感および舌や口腔粘膜の萎縮による舌炎・口角炎である. また, 輪状後部癌や頸部食道癌の高リスク因子であることはよく知られているが, 口腔癌との関連性も指摘されている. 今回我々は, Plummer-Vinson症候群に舌癌を伴った症例を経験した....
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| Published in | Stomato-pharyngology Vol. 23; no. 1; pp. 83 - 86 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本口腔・咽頭科学会
2010
Japan Society of Stomato-pharyngology |
| Subjects | |
| Online Access | Get full text |
| ISSN | 0917-5105 1884-4316 |
| DOI | 10.14821/stomatopharyngology.23.83 |
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| Abstract | Plummer Vinson症候群は, 鉄欠乏性貧血, 舌炎, 嚥下困難を三主徴とする疾患群で, 近年は栄養状態の改善もあり本邦では比較的稀な疾患である. 症状は動悸, 息切れ, 全身倦怠感などの貧血症状の他に, 輪状後部や頸部食道の粘膜萎縮・Web形成に基づく固形物の嚥下困難感および舌や口腔粘膜の萎縮による舌炎・口角炎である. また, 輪状後部癌や頸部食道癌の高リスク因子であることはよく知られているが, 口腔癌との関連性も指摘されている. 今回我々は, Plummer-Vinson症候群に舌癌を伴った症例を経験した. |
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| AbstractList | Plummer Vinson症候群は, 鉄欠乏性貧血, 舌炎, 嚥下困難を三主徴とする疾患群で, 近年は栄養状態の改善もあり本邦では比較的稀な疾患である. 症状は動悸, 息切れ, 全身倦怠感などの貧血症状の他に, 輪状後部や頸部食道の粘膜萎縮・Web形成に基づく固形物の嚥下困難感および舌や口腔粘膜の萎縮による舌炎・口角炎である. また, 輪状後部癌や頸部食道癌の高リスク因子であることはよく知られているが, 口腔癌との関連性も指摘されている. 今回我々は, Plummer-Vinson症候群に舌癌を伴った症例を経験した. The Plummer-Vinson syndrome is characterized by three main manifestations: iron deficiency anemia, glossitis and dysphagia. This syndrome has become relatively rare in recent years in Japan, because of the generally improved nutritional status of the subjects. The symptoms include difficulty in swallowing solid foods due to mucosal atrophy and web formation in the postcricoid region and cervical esophagus, and glossitis and angular stomatitis due to atrophy of the tongue and oral mucosa, in addition to symptoms of anemia, such as palpitation, shortness of breath and generalized fatigue. In addition, the syndrome is well known to be a high risk factor for postcricoid and cervical esophagus cancers, and a relationship with oral cancer has also been suggested. In the present report, we describe our experience of a case of Plummer-Vinson syndrome associated with tongue cancer. Plummer Vinson症候群は, 鉄欠乏性貧血, 舌炎, 嚥下困難を三主徴とする疾患群で, 近年は栄養状態の改善もあり本邦では比較的稀な疾患である. 症状は動悸, 息切れ, 全身倦怠感などの貧血症状の他に, 輪状後部や頸部食道の粘膜萎縮・Web形成に基づく固形物の嚥下困難感および舌や口腔粘膜の萎縮による舌炎・口角炎である. また, 輪状後部癌や頸部食道癌の高リスク因子であることはよく知られているが, 口腔癌との関連性も指摘されている. 今回我々は, Plummer-Vinson症候群に舌癌を伴った症例を経験した. |
| Author | 湯川, 尚哉 友田, 幸一 藤澤, 琢郎 竹村, 博一 近野, 哲史 永田, 基樹 井上, 俊哉 |
| Author_FL | Yukawa Hisaya Fujisawa Takuo Takemura Hirokazu Nagata Motoki Inoue Toshiya Chikano Tetsushi Tomoda Koichi |
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| DocumentTitleAlternate | A case of Plummer-Vinson syndrome associated with tongue cancer |
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| References | 9) Plummer HS. Diffuse dilatation of the esophagus without anatomic stenosis (cardiospasm): Report of 91 cases. JAMA 1912; 58: 2013-2015. 11) 林康司, 山家誠, 篠田鉄郎, 他: Plummer-Vinson症候群の舌炎から移行したと思われる舌背部扁平上皮癌. 頭頸部腫瘍 1989; 15: 192-196. 8) Vinson PP. Hysterical dysphagia. Minn. Med 1922; 5: 107-108. 6) Ahlbom HE. Simple achlorhydric anemia, Plummer-Vinson Syndrome, and carcinoma of the mouth, pharynx and esophagus in women. Br Med J 1936; 2: 331-333. 3) Suzman MM. Syndrome of anemia, glossitis and dysplasia; Report of eight cases, with special reference to observations at autopsy in one instance. Arch Int Med 1933; 51: 1-21. 7) Chisholm M. The association between webs, iron and postcricoid carcinoma. Postgrad Medical Journal 1974; 50: 215. 5) Jones RF. The Paterson-Brown Kelly syndrome. Its relationship to iron deficiency and postcricoid carcinoma. J Laryngol Otol 1961; 75: 529-543. 4) Walderstrom J. The roentgenological diagnosis of sideropenic dysphagia (Plummer-Vinson's syndrome). Acta Radiol 1939; 20: 618-638. 2) Rosof BM, Nagler RW. Plummer-Vinson Syndrome. New York State J Med 1975; 75: 414-415. 10) 桜井敏恵, 折田洋造, 永野隆治: 舌癌を伴ったPlummer-Vinson症候群の一例. 耳喉 1983; 55: 981-985. 1) Wynder EL, Fryer JH. Etiologic considerations of Plummer-Vinson (Paterson-Kely) Syndrome. Ann Intern Med 1958; 49: 1106-1128. |
| References_xml | – reference: 6) Ahlbom HE. Simple achlorhydric anemia, Plummer-Vinson Syndrome, and carcinoma of the mouth, pharynx and esophagus in women. Br Med J 1936; 2: 331-333. – reference: 8) Vinson PP. Hysterical dysphagia. Minn. Med 1922; 5: 107-108. – reference: 7) Chisholm M. The association between webs, iron and postcricoid carcinoma. Postgrad Medical Journal 1974; 50: 215. – reference: 3) Suzman MM. Syndrome of anemia, glossitis and dysplasia; Report of eight cases, with special reference to observations at autopsy in one instance. Arch Int Med 1933; 51: 1-21. – reference: 5) Jones RF. The Paterson-Brown Kelly syndrome. Its relationship to iron deficiency and postcricoid carcinoma. J Laryngol Otol 1961; 75: 529-543. – reference: 4) Walderstrom J. The roentgenological diagnosis of sideropenic dysphagia (Plummer-Vinson's syndrome). Acta Radiol 1939; 20: 618-638. – reference: 9) Plummer HS. Diffuse dilatation of the esophagus without anatomic stenosis (cardiospasm): Report of 91 cases. JAMA 1912; 58: 2013-2015. – reference: 10) 桜井敏恵, 折田洋造, 永野隆治: 舌癌を伴ったPlummer-Vinson症候群の一例. 耳喉 1983; 55: 981-985. – reference: 11) 林康司, 山家誠, 篠田鉄郎, 他: Plummer-Vinson症候群の舌炎から移行したと思われる舌背部扁平上皮癌. 頭頸部腫瘍 1989; 15: 192-196. – reference: 1) Wynder EL, Fryer JH. Etiologic considerations of Plummer-Vinson (Paterson-Kely) Syndrome. Ann Intern Med 1958; 49: 1106-1128. – reference: 2) Rosof BM, Nagler RW. Plummer-Vinson Syndrome. New York State J Med 1975; 75: 414-415. |
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| Snippet | Plummer Vinson症候群は, 鉄欠乏性貧血, 舌炎, 嚥下困難を三主徴とする疾患群で, 近年は栄養状態の改善もあり本邦では比較的稀な疾患である. 症状は動悸, 息切れ, 全身倦怠感などの貧血症状の他に,... The Plummer-Vinson syndrome is characterized by three main manifestations: iron deficiency anemia, glossitis and dysphagia. This syndrome has become relatively... |
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| StartPage | 83 |
| SubjectTerms | esophageal cancer iron deficiency anemia postcricoid cancer tongue cancer 舌癌 輪状後部癌 鉄欠乏性貧血 食道癌 |
| Title | Plummer-Vinson症候群に舌癌を伴った1症例 |
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