胎児鏡下胎盤吻合血管レーザー凝固術を導入してから当院で管理した一絨毛膜二羊膜双胎の短期予後と先天異常
当院で胎児鏡下吻合血管レーザー凝固術(fetoscopic laser photocoagulation of placental vessels:FLP)導入後に管理した一絨毛膜二羊膜(monochorionic diamniotic:MD)双胎の短期予後および先天異常につき検討した.対象は2016年8月から2018年9月に管理したMD双胎92組184例で,生存率は全体の89.1%,FLPを施行したTTTS群は85.9%,FLPを施行したsIUGR群は67.9%,FLP非施行群は100%だった.一児子宮内胎児死亡(intrauterine fetal death:IUFD)は18例(19.6...
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Published in | 日本周産期・新生児医学会雑誌 Vol. 57; no. 3; pp. 499 - 505 |
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Main Authors | , , , , , , , , , , , , , |
Format | Journal Article |
Language | Japanese |
Published |
一般社団法人 日本周産期・新生児医学会
2021
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Online Access | Get full text |
ISSN | 1348-964X 2435-4996 |
DOI | 10.34456/jjspnm.57.3_499 |
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Abstract | 当院で胎児鏡下吻合血管レーザー凝固術(fetoscopic laser photocoagulation of placental vessels:FLP)導入後に管理した一絨毛膜二羊膜(monochorionic diamniotic:MD)双胎の短期予後および先天異常につき検討した.対象は2016年8月から2018年9月に管理したMD双胎92組184例で,生存率は全体の89.1%,FLPを施行したTTTS群は85.9%,FLPを施行したsIUGR群は67.9%,FLP非施行群は100%だった.一児子宮内胎児死亡(intrauterine fetal death:IUFD)は18例(19.6%),新生児死亡は1例(0.6%)であった.先天異常は全体の9.8%だった.FLP導入以降のMD双胎の短期予後は既報と同じく良好であった.また,先天異常は一般頻度と比べ高率であった. |
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AbstractList | 当院で胎児鏡下吻合血管レーザー凝固術(fetoscopic laser photocoagulation of placental vessels:FLP)導入後に管理した一絨毛膜二羊膜(monochorionic diamniotic:MD)双胎の短期予後および先天異常につき検討した.対象は2016年8月から2018年9月に管理したMD双胎92組184例で,生存率は全体の89.1%,FLPを施行したTTTS群は85.9%,FLPを施行したsIUGR群は67.9%,FLP非施行群は100%だった.一児子宮内胎児死亡(intrauterine fetal death:IUFD)は18例(19.6%),新生児死亡は1例(0.6%)であった.先天異常は全体の9.8%だった.FLP導入以降のMD双胎の短期予後は既報と同じく良好であった.また,先天異常は一般頻度と比べ高率であった. |
Author | 鷹野, 真由実 石嶺, 里枝 森谷, 菜央 水書, 教雄 与田, 仁志 中田, 雅彦 荒井, 博子 緒方, 公平 斉藤, 敬子 日根, 幸太郎 長崎, 澄人 川瀬, 泰浩 豊田, 理奈 村井, 裕香 |
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References | 2) Karatza AA, Wolfenden JL, Taylor MJ, et al.:Influence of twin-twin transfusion syndrome on fetal cardiovascular structure and function:prospective case-control study of 136 monochorionic twin pregnancies. Heart 2002;88:271-277 10) Buca D, Pagani G, Rizzo G, et al.:Outcome of monochorionic twin pregnancy with selective intrauterine growth restriction according to umbilical artery doppler flow pattern of smaller twin: Systematic review and meta‐analysis. Ultrasound in Obstetrics & Gynecology 2016;50(5):559-568 1) Bahtiyar M, Dulay A, Weeks B, et al.:Prevalence of congenital heart defects in monochorionic/diamniotic twin gestations:A systematic literature review. Journal of Ultrasound in Medicine 2007;26(11):1491-1498 20) Yoda H:Fetal and Neonatal Circulatory Disorders in Twin to Twin Transfusion Syndrome(The Secondary Publication). J Nippon Med Sch 2019;86(4):192-200 15) 芦名満理子,藤岡一路,福嶋祥代,ほか:重症small for gestational age児における尿道下裂合併症例とその出生時臨床像の検討.小児科臨床 2018;71(2):180-184 7) 村越毅,上田敏子,松本美奈子,ほか:多胎妊娠における諸問題 多胎妊娠の短期および長期予後の検討.日本周産期・新生児医学会雑誌 2005;41(4),750-755 22) Moon-Grady J, Rand L, Lemley B, et al.:Effect of selective fetoscopic laser photocoagulation therapy for twin-twin transfusion syndrome on pulmonary valve pathology in recipient twins. Ultrasound in Obstetrics & Gynecology:The Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology 2011;37(1):27-33 4) Ishii K, Nakata M, Wada S, et al.:Feasibility and preliminary outcomes of fetoscopic laser photocoagulation for monochorionic twin gestation with selective intrauterine growth restriction accompanied by severe oligohydramnios. Journal of Obstetrics and Gynaecology Research 2015;41(11):1732-1737 9) Akkermans J, Peeters S, Klumper J, et al.:Twenty-five years of fetoscopic laser coagulation in twin-twin transfusion syndrome. A systematic review. Fetal Diagnosis and Therapy 2015;38(4):241-253 21) Murata S, Nakata M, Norihiro S:Prevalence of right ventricular outflow tract abnormalities among recipients in twin-twin transfusion syndrome after fetoscopic laser surgery in 90 consecutive cases. Journal of Medical Ultrasonics 2020;47:117-121 5) 中田雅彦:TTTSの診断と病態.村越毅編集.多胎妊娠 妊娠・分娩・新生児管理のすべて.東京:メジカルビュー社,2015:146-161 8) Lewi L, Jani J, Blickstein I, et al.:The outcome of monochorionic diamniotic twin gestations in the era of invasive fetal therapy. A prospective cohort study. American Journal of Obstetrics and Gynecology 2008;199(5):514 12) Ishii K, Wada S, Takano M, et al.:Survival Rate without Brain Abnormalities on Postnatal Ultrasonography among Monochorionic Twins after Fetoscopic Laser Photocoagulation for Selective Intrauterine Growth Restriction with Concomitant Oligohydramnios. Fetal Diagn Ther 2019;45:21-27 14) 切原奈美,前田隆嗣,上塘正人:多胎妊娠にみられる胎児形態異常.周産期医学 2010;40(3):311-315 18) 松岡瑠美子,森克彦,安藤正彦:先天性心疾患の疫学調査.日児誌 1986;90:2578-2587 19) 与田仁志:TTTSの新生児循環障害.周産期医学2015;45(1):37-43 11) Gratacos E, Antolin E, Lewi L, et al.:Monochorionic twins with selective intrauterine growth restriction and intermittent absent or reversed end-diastolic flow(Type III). Ultrasound Obstetrics and Gynecology 2008;31:669-675 13) Layde P, Erickson D, Falek A, et al.:Congenital malformation in twins. American Journal of Human Genetics 1980;32(1):69-78 16) Manning N, Archer N:A study to determine the incidence of structural congenital heart disease in monochorionic twins. Prenat Diagn 2006;26:1062-1064 17) Pettit KE, Merchant M, Machin GA, et al.:Congenital heart defects in a large, unselected cohort of monochorionic twins. Journal of Perinatology 2013;33(6):457-461 3) Lewi L, Gucciardo L, Van Mieghem T, et al.:Monochorionic diamniotic twin pregnancies:Natural history and risk stratification. Fetal Diagnosis and Therapy 2010;27(3):121-133 6) 石井桂介:selective IUGRの診断と治療.村越毅編集.多胎妊娠 妊娠・分娩・新生児管理のすべて.東京:メジカルビュー社,2015:170-179 |
References_xml | – reference: 13) Layde P, Erickson D, Falek A, et al.:Congenital malformation in twins. American Journal of Human Genetics 1980;32(1):69-78 – reference: 2) Karatza AA, Wolfenden JL, Taylor MJ, et al.:Influence of twin-twin transfusion syndrome on fetal cardiovascular structure and function:prospective case-control study of 136 monochorionic twin pregnancies. Heart 2002;88:271-277 – reference: 9) Akkermans J, Peeters S, Klumper J, et al.:Twenty-five years of fetoscopic laser coagulation in twin-twin transfusion syndrome. A systematic review. Fetal Diagnosis and Therapy 2015;38(4):241-253 – reference: 16) Manning N, Archer N:A study to determine the incidence of structural congenital heart disease in monochorionic twins. Prenat Diagn 2006;26:1062-1064 – reference: 1) Bahtiyar M, Dulay A, Weeks B, et al.:Prevalence of congenital heart defects in monochorionic/diamniotic twin gestations:A systematic literature review. Journal of Ultrasound in Medicine 2007;26(11):1491-1498 – reference: 22) Moon-Grady J, Rand L, Lemley B, et al.:Effect of selective fetoscopic laser photocoagulation therapy for twin-twin transfusion syndrome on pulmonary valve pathology in recipient twins. Ultrasound in Obstetrics & Gynecology:The Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology 2011;37(1):27-33 – reference: 15) 芦名満理子,藤岡一路,福嶋祥代,ほか:重症small for gestational age児における尿道下裂合併症例とその出生時臨床像の検討.小児科臨床 2018;71(2):180-184 – reference: 12) Ishii K, Wada S, Takano M, et al.:Survival Rate without Brain Abnormalities on Postnatal Ultrasonography among Monochorionic Twins after Fetoscopic Laser Photocoagulation for Selective Intrauterine Growth Restriction with Concomitant Oligohydramnios. Fetal Diagn Ther 2019;45:21-27 – reference: 19) 与田仁志:TTTSの新生児循環障害.周産期医学2015;45(1):37-43 – reference: 4) Ishii K, Nakata M, Wada S, et al.:Feasibility and preliminary outcomes of fetoscopic laser photocoagulation for monochorionic twin gestation with selective intrauterine growth restriction accompanied by severe oligohydramnios. Journal of Obstetrics and Gynaecology Research 2015;41(11):1732-1737 – reference: 17) Pettit KE, Merchant M, Machin GA, et al.:Congenital heart defects in a large, unselected cohort of monochorionic twins. Journal of Perinatology 2013;33(6):457-461 – reference: 14) 切原奈美,前田隆嗣,上塘正人:多胎妊娠にみられる胎児形態異常.周産期医学 2010;40(3):311-315 – reference: 5) 中田雅彦:TTTSの診断と病態.村越毅編集.多胎妊娠 妊娠・分娩・新生児管理のすべて.東京:メジカルビュー社,2015:146-161 – reference: 18) 松岡瑠美子,森克彦,安藤正彦:先天性心疾患の疫学調査.日児誌 1986;90:2578-2587 – reference: 20) Yoda H:Fetal and Neonatal Circulatory Disorders in Twin to Twin Transfusion Syndrome(The Secondary Publication). J Nippon Med Sch 2019;86(4):192-200 – reference: 10) Buca D, Pagani G, Rizzo G, et al.:Outcome of monochorionic twin pregnancy with selective intrauterine growth restriction according to umbilical artery doppler flow pattern of smaller twin: Systematic review and meta‐analysis. Ultrasound in Obstetrics & Gynecology 2016;50(5):559-568 – reference: 3) Lewi L, Gucciardo L, Van Mieghem T, et al.:Monochorionic diamniotic twin pregnancies:Natural history and risk stratification. Fetal Diagnosis and Therapy 2010;27(3):121-133 – reference: 6) 石井桂介:selective IUGRの診断と治療.村越毅編集.多胎妊娠 妊娠・分娩・新生児管理のすべて.東京:メジカルビュー社,2015:170-179 – reference: 8) Lewi L, Jani J, Blickstein I, et al.:The outcome of monochorionic diamniotic twin gestations in the era of invasive fetal therapy. A prospective cohort study. American Journal of Obstetrics and Gynecology 2008;199(5):514 – reference: 11) Gratacos E, Antolin E, Lewi L, et al.:Monochorionic twins with selective intrauterine growth restriction and intermittent absent or reversed end-diastolic flow(Type III). Ultrasound Obstetrics and Gynecology 2008;31:669-675 – reference: 21) Murata S, Nakata M, Norihiro S:Prevalence of right ventricular outflow tract abnormalities among recipients in twin-twin transfusion syndrome after fetoscopic laser surgery in 90 consecutive cases. Journal of Medical Ultrasonics 2020;47:117-121 – reference: 7) 村越毅,上田敏子,松本美奈子,ほか:多胎妊娠における諸問題 多胎妊娠の短期および長期予後の検討.日本周産期・新生児医学会雑誌 2005;41(4),750-755 |
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Title | 胎児鏡下胎盤吻合血管レーザー凝固術を導入してから当院で管理した一絨毛膜二羊膜双胎の短期予後と先天異常 |
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