Gender differences in healthy aging and Alzheimer's Dementia: A 18F‐FDG‐PET study of brain and cognitive reserve

• Published in: Human brain mapping Vol. 38; no. 8; pp. 4212 - 4227
• Main Authors: Malpetti, Maura, Ballarini, Tommaso, Presotto, Luca, Garibotto, Valentina, Tettamanti, Marco, Perani, Daniela
• Format: Journal Article
• Language: English
• Published: San Antonio John Wiley & Sons, Inc 01.08.2017; John Wiley and Sons Inc
• Subjects: Aging; Aging (artificial); Alzheimer's Dementia; Alzheimer's disease; Brain; brain reserve; Cognitive ability; cognitive reserve; Cortex (frontal); Dementia; Dementia disorders; Disorders; Education; Females; Fluorine‐18‐Flourodeoxiglucose; gender; Gender aspects; Gender differences; Geriatrics; healthy aging; Hypometabolism; Males; Metabolism; Modulation; Neural networks; Neurodegenerative diseases; Neuroimaging; occupation; Occupations; Older people; Patients; Positron emission tomography; Sex differences

Cognitive reserve (CR) and brain reserve (BR) are protective factors against age‐associated cognitive decline and neurodegenerative disorders. Very limited evidence exists about gender effects on brain aging and on the effect of CR on brain modulation in healthy aging and Alzheimer's Dementia (...