Biological Profiling of Gene Groups utilizing Gene Ontology

• Published in: Genome Informatics Vol. 16; no. 1; pp. 106 - 115
• Main Authors: Cajavec, Branka, Herzel, Hanspeter, Swat, Maciej, Beule, Dieter, Brand, Karsten, Blüthgen, Nils
• Format: Journal Article
• Language: English
• Published: Japan Japanese Society for Bioinformatics 2005
• Subjects: Binding Sites - genetics; Cell Cycle - genetics; Cell Cycle - physiology; Data Interpretation, Statistical; False Positive Reactions; G1 Phase; G2 Phase; Gene Expression Profiling; Gene Frequency; gene groups; gene ontology; HeLa Cells; Humans; interpretation of high-throughput data; Mitosis; Models, Statistical; multiple testing; Oligonucleotide Array Sequence Analysis; Reference Standards; Reproducibility of Results; S Phase; Software; Transcription Factors - metabolism; Up-Regulation

Increasingly used high throughput experimental techniques, like DNA or protein rnicroarrays give as a result groups of interesting, e.g. differentially regulated genes which require further biological interpretation. With the systematic functional annotation provided by the Gene Ontology the informa...