Dietary nitrate supplementation: effects on plasma nitrite and pulmonary O2 uptake dynamics during exercise in hypoxia and normoxia

• Published in: American journal of physiology. Regulatory, integrative and comparative physiology Vol. 307; no. 7; p. R920
• Main Authors: Kelly, James, Vanhatalo, Anni, Bailey, Stephen J, Wylie, Lee J, Tucker, Christopher, List, Stephen, Winyard, Paul G, Jones, Andrew M
• Format: Journal Article
• Language: English
• Published: United States 01.10.2014
• Subjects: Adolescent; Adult; Blood Pressure - drug effects; Blood Pressure - physiology; Dietary Supplements; Double-Blind Method; Exercise - physiology; Exercise Tolerance - physiology; Humans; Male; Muscle, Skeletal - drug effects; Nitrates - pharmacology; Nitrites - blood; Oxygen - metabolism; Oxygen Consumption - physiology; Young Adult; hypoxia; beetroot juice; efficiency; nitric oxide; performance

We investigated the effects of dietary nitrate (NO3 (-)) supplementation on the concentration of plasma nitrite ([NO2 (-)]), oxygen uptake (V̇o2) kinetics, and exercise tolerance in normoxia (N) and hypoxia (H). In a double-blind, crossover study, 12 healthy subjects completed cycle exercise tests,...