Strategies for Genome Reduction in Microbial Genomes

• Published in: Genome Informatics Vol. 16; no. 2; pp. 69 - 75
• Main Authors: Sakharkar, Kishore R., Chow, Vincent T.K.
• Format: Journal Article
• Language: English
• Published: Japan Japanese Society for Bioinformatics 2005
• Subjects: Bacteria - genetics; Computational Biology - methods; Evolution, Molecular; Gene Deletion; Genes, Overlapping; genome reduction; Genome, Bacterial; minimal genomes; obligatory intracellular parasites; overlapping genes; overprinting; Structural Homology, Protein

Niche dependent differential gene loss and overlapping genes have been proposed as means of achieving genome reduction by retaining indispensable genes and compressing maximum amount of information in available sequence space. Herein, we analyzed the differential gene loss and overlapping genes in b...