Structural Analysis of Expanding Metabolic Networks

• Published in: Genome Informatics Vol. 15; no. 1; pp. 35 - 45
• Main Authors: Ebenhöh, Oliver, Handorf, Thomas, Heinrich, Reinhart
• Format: Journal Article
• Language: English
• Published: Japan Japanese Society for Bioinformatics 2004
• Subjects: Databases, Factual; evolution; Glycolysis; KEGG database; Kinetics; metabolic network; Metabolism; Models, Biological; Nerve Net; optimisation; Phosphates - metabolism; scope; stoichiometry

Methods are developed for structural analysis of metabolic networks expanding in size. Expansion proceeds in consecutive generations in which new reactions are attached to the network produced in the previous stage. Different rules are applied resulting in various modes of expansion. Expansion is pe...