脳動脈瘤に対する血流解析専用ソフトウェアを用いた,解析条件の標準化および増大予測の検討─ファントム実験および臨床例を含めて

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Published in日本放射線技術学会雑誌 Vol. 74; no. 11; pp. 1275 - 1285
Main Authors 橘高, 大介, 加藤, 京一, 佐藤, 久弥, 中井, 雄一, 野田, 主税, 濱田, 裕貴
Format Journal Article
LanguageJapanese
Published 公益社団法人 日本放射線技術学会 2018
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ISSN0369-4305
1881-4883
DOI10.6009/jjrt.2018_JSRT_74.11.1275

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Author 野田, 主税
橘高, 大介
中井, 雄一
濱田, 裕貴
佐藤, 久弥
加藤, 京一
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  organization: 学校法人昭和大学統括放射線技術部
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  fullname: 佐藤, 久弥
  organization: 昭和大学大学院保健医療学研究科
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  fullname: 中井, 雄一
  organization: 昭和大学横浜市北部病院放射線技術部
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  fullname: 野田, 主税
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References 20) 八木高伸.循環器疾患のための次世代診断治療支援技術:血流シミュレーション.INNERVISION 2016; 31(10): 42–43.
27) 笹森大輔.数値流体力学 (CFD) 解析の活用.INNERVISION 2016; 31(10): 17–21.
11) Vlak MH, Rinkel GJ, Greebe P, et al. Risk of rupture of an intracranial aneurysm based on patient characteristics: a case-control study. Stroke 2013; 44(5): 1256–1259.
16) 高尾洋之,山本誠,大塚忍,他.数値流体力学 (CFD) を用いた脳動脈瘤解析.脳神外ジャーナル2012; 21(4): 298–305.
23) 日本放射線技術学会撮影部会編.推奨プロトコル:10–12.X 線CT 撮影における標準化~GALACTIC~ (改訂2版) .日本放射線技術学会,京都,2015: 8.
5) Tsutsumi K, Ueki K, Morita A, et al. Risk of rupture from incidental cerebral aneurysms. J Neurosurg 2000; 93(4): 550–553.
3) Huang MC, Baaj AA, Downes K, et al. Paradoxical trends in the management of unruptured cerebral aneurysms in the United States: analysis of nationwide database over a 10-year period. Stroke 2011; 42(6): 1730–1735.
18) 森大祐,山口隆美.大動脈瘤の発症における大動脈内血流の影響の計算流体力学的解析.日本脈管学会機関誌2003; 43(3): 94–97.
1) Wiebers DO, Whisnant JP, Huston J, et al. Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. Lancet 2003; 362 (9378): 103–110.
9) Raghavan ML, Ma B, Harbaugh RE. Quantified aneurysm shape and rupture risk. J Neurosurg 2005; 102(2): 355–362.
10) Wermer MJ, van der Schaaf IC, Algra A, et al. Risk of rupture of unruptured intracranial aneurysms in relation to patient and aneurysm characteristics: an updated meta-analysis. Stroke 2007; 38(4): 1404–1410.
26) Boussel L, Rayz V, McCulloch C, et al. Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study. Stroke 2008; 39(11): 2997–3002.
2) Raaymakers TW, Rinkel GJ, Limburg M, et al. Mortality and morbidity of surgery for unruptured intracranial aneurysms: a meta-analysis. Stroke 1998; 29(8): 1531–1538.
13) Raaymakers TW. Functional outcome and quality of life after angiography and operation for unruptured intracranial aneurysms. On behalf of the MARS Study Group. J Neurol Neurosurg Psychiatry 2000; 68(5): 571–576.
7) Juvela S, Porras M, Poussa K. Natural history of unruptured intracranial aneurysms: probability of and risk factors for aneurysm rupture. J Neurosurg 2000; 93(3): 379–387.
24) 平野透,井田義宏,石風呂実,他.2-1 頭部.超実践マニュアルCT.医療科学社,東京,2006: 80–81.
8) Ujiie H, Tamano Y, Sasaki K, et al. Is the aspect ratio a reliable index for predicting the rupture of a saccular aneurysm? Neurosurgery 2001; 48(3): 495–502: discussion 502–503.
15) Yamashiro S, Nishi T, Koga K, et al. Improvement of quality of life in patients surgically treated for asymptomatic unruptured intracranial aneurysms. J Neurol Neurosurg Psychiatry 2007; 78(5): 497–500.
14) Brilstra EH, Rinkel GJ, van der Graaf Y, et al. Quality of life after treatment of unruptured intracranial aneurysms by neurosurgical clipping or by embolisation with coils. A prospective, observational study. Cerebrovasc Dis 2004; 17(1): 44–52.
22) 柳澤毅,高尾洋之,小田淳平.脳動脈瘤の開頭直達手術とCFD~直視下観察による瘤壁の性状と局所圧の関係に着目して~.脳外速報2014; 24(10): 1116–1121.
4) Otawara Y, Ogasawara K, Kubo Y, et al. Anxiety before and after surgical repair in patients with asymptomatic unruptured intracranial aneurysm. Surg Neurol 2004; 62 (1): 28–31; discussion 31.
6) Morita A, Fujiwara S, Hashi K, et al. Risk of rupture associated with intact cerebral aneurysms in the Japanese population: a systematic review of the literature from Japan. J Neurosurg 2005; 102(4): 601–606.
17) 野狩猛,和田成生,内貴猛.血管病の局在化におよぼす物理的・流体力学的因子の影響.北海道大学電子科学研究所: 1997; 4: 22–32.
25) Cebral JR, Mut F, Weir J, et al. Quantitative characterization of the hemodynamic environment in ruptured and unruptured brain aneurysms. AJNR Am J Neuroradiol 2011; 32(1): 145–151.
12) Tremmel M, Dhar S, Levy EI, et al. Influence of intracranial aneurysm-to-parent vessel size ratio on hemodynamics and implication for rupture: results from a virtual experimental study. Neurosurgery 2009; 64(4): 622–630; discussion 630–631.
19) 八木高伸.数値流体力学 (CFD) を原理から現場へ~血流を診る~.脳神経外科速報2013; 23(10): 1120–1125.
21) Hashimoto T. Dynamic measurement of pressure and flow velocities in glass and silastic model berry aneurysms. Neurol Res 1984; 6(1–2): 22–28.
References_xml – reference: 9) Raghavan ML, Ma B, Harbaugh RE. Quantified aneurysm shape and rupture risk. J Neurosurg 2005; 102(2): 355–362.
– reference: 21) Hashimoto T. Dynamic measurement of pressure and flow velocities in glass and silastic model berry aneurysms. Neurol Res 1984; 6(1–2): 22–28.
– reference: 7) Juvela S, Porras M, Poussa K. Natural history of unruptured intracranial aneurysms: probability of and risk factors for aneurysm rupture. J Neurosurg 2000; 93(3): 379–387.
– reference: 19) 八木高伸.数値流体力学 (CFD) を原理から現場へ~血流を診る~.脳神経外科速報2013; 23(10): 1120–1125.
– reference: 11) Vlak MH, Rinkel GJ, Greebe P, et al. Risk of rupture of an intracranial aneurysm based on patient characteristics: a case-control study. Stroke 2013; 44(5): 1256–1259.
– reference: 1) Wiebers DO, Whisnant JP, Huston J, et al. Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. Lancet 2003; 362 (9378): 103–110.
– reference: 13) Raaymakers TW. Functional outcome and quality of life after angiography and operation for unruptured intracranial aneurysms. On behalf of the MARS Study Group. J Neurol Neurosurg Psychiatry 2000; 68(5): 571–576.
– reference: 27) 笹森大輔.数値流体力学 (CFD) 解析の活用.INNERVISION 2016; 31(10): 17–21.
– reference: 26) Boussel L, Rayz V, McCulloch C, et al. Aneurysm growth occurs at region of low wall shear stress: patient-specific correlation of hemodynamics and growth in a longitudinal study. Stroke 2008; 39(11): 2997–3002.
– reference: 6) Morita A, Fujiwara S, Hashi K, et al. Risk of rupture associated with intact cerebral aneurysms in the Japanese population: a systematic review of the literature from Japan. J Neurosurg 2005; 102(4): 601–606.
– reference: 23) 日本放射線技術学会撮影部会編.推奨プロトコル:10–12.X 線CT 撮影における標準化~GALACTIC~ (改訂2版) .日本放射線技術学会,京都,2015: 8.
– reference: 25) Cebral JR, Mut F, Weir J, et al. Quantitative characterization of the hemodynamic environment in ruptured and unruptured brain aneurysms. AJNR Am J Neuroradiol 2011; 32(1): 145–151.
– reference: 18) 森大祐,山口隆美.大動脈瘤の発症における大動脈内血流の影響の計算流体力学的解析.日本脈管学会機関誌2003; 43(3): 94–97.
– reference: 3) Huang MC, Baaj AA, Downes K, et al. Paradoxical trends in the management of unruptured cerebral aneurysms in the United States: analysis of nationwide database over a 10-year period. Stroke 2011; 42(6): 1730–1735.
– reference: 12) Tremmel M, Dhar S, Levy EI, et al. Influence of intracranial aneurysm-to-parent vessel size ratio on hemodynamics and implication for rupture: results from a virtual experimental study. Neurosurgery 2009; 64(4): 622–630; discussion 630–631.
– reference: 16) 高尾洋之,山本誠,大塚忍,他.数値流体力学 (CFD) を用いた脳動脈瘤解析.脳神外ジャーナル2012; 21(4): 298–305.
– reference: 5) Tsutsumi K, Ueki K, Morita A, et al. Risk of rupture from incidental cerebral aneurysms. J Neurosurg 2000; 93(4): 550–553.
– reference: 20) 八木高伸.循環器疾患のための次世代診断治療支援技術:血流シミュレーション.INNERVISION 2016; 31(10): 42–43.
– reference: 22) 柳澤毅,高尾洋之,小田淳平.脳動脈瘤の開頭直達手術とCFD~直視下観察による瘤壁の性状と局所圧の関係に着目して~.脳外速報2014; 24(10): 1116–1121.
– reference: 8) Ujiie H, Tamano Y, Sasaki K, et al. Is the aspect ratio a reliable index for predicting the rupture of a saccular aneurysm? Neurosurgery 2001; 48(3): 495–502: discussion 502–503.
– reference: 17) 野狩猛,和田成生,内貴猛.血管病の局在化におよぼす物理的・流体力学的因子の影響.北海道大学電子科学研究所: 1997; 4: 22–32.
– reference: 14) Brilstra EH, Rinkel GJ, van der Graaf Y, et al. Quality of life after treatment of unruptured intracranial aneurysms by neurosurgical clipping or by embolisation with coils. A prospective, observational study. Cerebrovasc Dis 2004; 17(1): 44–52.
– reference: 4) Otawara Y, Ogasawara K, Kubo Y, et al. Anxiety before and after surgical repair in patients with asymptomatic unruptured intracranial aneurysm. Surg Neurol 2004; 62 (1): 28–31; discussion 31.
– reference: 2) Raaymakers TW, Rinkel GJ, Limburg M, et al. Mortality and morbidity of surgery for unruptured intracranial aneurysms: a meta-analysis. Stroke 1998; 29(8): 1531–1538.
– reference: 10) Wermer MJ, van der Schaaf IC, Algra A, et al. Risk of rupture of unruptured intracranial aneurysms in relation to patient and aneurysm characteristics: an updated meta-analysis. Stroke 2007; 38(4): 1404–1410.
– reference: 15) Yamashiro S, Nishi T, Koga K, et al. Improvement of quality of life in patients surgically treated for asymptomatic unruptured intracranial aneurysms. J Neurol Neurosurg Psychiatry 2007; 78(5): 497–500.
– reference: 24) 平野透,井田義宏,石風呂実,他.2-1 頭部.超実践マニュアルCT.医療科学社,東京,2006: 80–81.
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SubjectTerms blood flow analysis software
computational fluid dynamics (CFD)
unruptured aneurysm
wall pressure (WP)
wall shear stress (WSS)
Title 脳動脈瘤に対する血流解析専用ソフトウェアを用いた,解析条件の標準化および増大予測の検討─ファントム実験および臨床例を含めて
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