危機の時代に立つ,これからの麻酔科医

新型コロナウイルス感染症(COVID-19)によるパンデミック,それによる医療現場の逼迫の影響は,麻酔科医を含むあらゆる医師に,基礎研究のみならず臨床研究・公衆衛生学の重要性を再認識させた.従来の医学研究は基礎研究に偏重していたため,今後の麻酔科医には未曾有の危機にも対応できるようなバランスのとれた医学知識を涵養する必要があると考える.本稿は,COVID-19に関連する周術期のトピックに関して,麻酔科医にとって特に重要と考えられる最新の論文とその知見の概要を提示する....

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Published in日本臨床麻酔学会誌 Vol. 41; no. 5; pp. 502 - 508
Main Authors 米倉, 寛, 角渕, 浩央, 武田, 親宗
Format Journal Article
LanguageJapanese
Published 日本臨床麻酔学会 15.09.2021
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ISSN0285-4945
1349-9149
DOI10.2199/jjsca.41.502

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Abstract 新型コロナウイルス感染症(COVID-19)によるパンデミック,それによる医療現場の逼迫の影響は,麻酔科医を含むあらゆる医師に,基礎研究のみならず臨床研究・公衆衛生学の重要性を再認識させた.従来の医学研究は基礎研究に偏重していたため,今後の麻酔科医には未曾有の危機にも対応できるようなバランスのとれた医学知識を涵養する必要があると考える.本稿は,COVID-19に関連する周術期のトピックに関して,麻酔科医にとって特に重要と考えられる最新の論文とその知見の概要を提示する.
AbstractList [要旨] 新型コロナウイルス感染症(COVID-19)によるパンデミック, それによる医療現場の逼迫の影響は, 麻酔科医を含むあらゆる医師に, 基礎研究のみならず臨床研究・公衆衛生学の重要性を再認識させた. 従来の医学研究は基礎研究に偏重していたため, 今後の麻酔科医には未曾有の危機にも対応できるようなバランスのとれた医学知識を涵養する必要があると考える. 本稿は, COVID-19に関連する周術期のトピックに関して, 麻酔科医にとって特に重要と考えられる最新の論文とその知見の概要を提示する.
新型コロナウイルス感染症(COVID-19)によるパンデミック,それによる医療現場の逼迫の影響は,麻酔科医を含むあらゆる医師に,基礎研究のみならず臨床研究・公衆衛生学の重要性を再認識させた.従来の医学研究は基礎研究に偏重していたため,今後の麻酔科医には未曾有の危機にも対応できるようなバランスのとれた医学知識を涵養する必要があると考える.本稿は,COVID-19に関連する周術期のトピックに関して,麻酔科医にとって特に重要と考えられる最新の論文とその知見の概要を提示する.
Author 米倉, 寛
角渕, 浩央
武田, 親宗
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References 4) COVIDSurg Collaborative:Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic. Br J Surg 108:88-96, 2021
5) COVIDSurg Collaborative:Elective surgery cancellations due to the COVID-19 pandemic:global predictive modelling to inform surgical recovery plans. Br J Surg 107:1440-1449, 2020
20) Woloshin S, Patel N, Kesselheim AS:False Negative Tests for SARS-CoV-2 Infection - Challenges and Implications. N Engl J Med 383:e38, 2020
18) Arevalo-Rodriguez I, Buitrago-Garcia D, Simancas-Racines D, et al.:False-negative results of initial RT-PCR assays for COVID-19:A systematic review. PloS One 15:e0242958, 2020
19) Watson J, Whiting PF, Brush JE:Interpreting a covid-19 test result. BMJ 369:m1808, 2020
7) COVIDSurg Collaborative, GlobalSurg Collaborative:SARS-CoV-2 vaccination modelling for safe surgery to save lives:data from an international prospective cohort study. Br J Surg, 2021;doi:10.1093/bjs/znab101[Epub ahead of print]
23) Raffle AE, Gill M:Mass screening for asymptomatic SARS-CoV-2 infection. BMJ 373:n1058, 2021
24) Salluh JIF, Arabi YM, Binnie A:COVID-19 research in critical care:the good, the bad, and the ugly. Intensive Care Med 47:470-472, 2021
16) Kirmeier E, Eriksson LI, Lewald H, et al.:Post-anaesthesia pulmonary complications after use of muscle relaxants(POPULAR):a multicentre, prospective observational study. Lancet Respir Med 7:129-140, 2019
14) Fan E, Beitler JR, Brochard L, et al.:COVID-19-associated acute respiratory distress syndrome:is a different approach to management warranted? Lancet Respir Med 8:816-821, 2020
17) 公益社団法人 日本麻酔科学会(2020):新型コロナウイルス感染症(COVID-19)に関する本学会の対応. 〈https://anesth.or.jp/img/upload/ckeditor/files/2004_07_09.pdf〉(2021.4.1閲覧)
21) Hall J, Myall K, Lam JL, et al.:Identifying patients at risk of post-discharge complications related to COVID-19 infection. Thorax 76:408-411, 2021
9) El-Boghdadly K, Cook TM, Goodacre T, et al.:SARS-CoV-2 infection, COVID-19 and timing of elective surgery:A multidisciplinary consensus statement on behalf of the Association of Anaesthetists, the Centre for Peri-operative Care, the Federation of Surgical Specialty Associations, the Royal College of Anaesthetists and the Royal College of Surgeons of England. Anaesthesia 76:940-946, 2021
13) Cummings MJ, Baldwin MR, Abrams D, et al.:Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City:a prospective cohort study. Lancet 395:1763-1770, 2020
22) Zarocostas J:How to fight an infodemic. Lancet 395:676, 2020
8) 厚生労働省:データからわかる─新型コロナウイルス感染症情報─.〈https://covid19.mhlw.go.jp/〉(2021.4.1閲覧)
1) The Center for Systems Science and Engineering(CSSE)at Johns Hopkins University(2020):COVID-19 Dashboard.〈https://gisanddata.maps.arcgis.com/apps/dashboards/bda7594740fd40299423467b48e9ecf6〉(2021.4.1閲覧)
12) Tsang JLY, Binnie A, Fowler RA:Twenty articles that critical care clinicians should read about COVID-19. Intensive Care Med 47:337-341, 2021
15) Glance LG, Lustik SJ, Hannan EL, et al.:The Surgical Mortality Probability Model:derivation and validation of a simple risk prediction rule for noncardiac surgery. Ann Surg 255:696-702, 2012
2) NIHR Global Health Research Unit on Global Surgery-CovidSurg(2020):About CovidSurg.〈https://globalsurg.org/covidsurg/〉(2021.4.1閲覧)
6) COVIDSurg Collaborative, GlobalSurg Collaborative:Timing of surgery following SARS-CoV-2 infection:an international prospective cohort study. Anaesthesia 76:748-758, 2021
10) Gattinoni L, Chiumello D, Caironi P, et al.:COVID-19 pneumonia:different respiratory treatments for different phenotypes? Intensive Care Med 46:1099-1102, 2020
11) Grasselli G, Tonetti T, Protti A, et al.:Pathophysiology of COVID-19-associated acute respiratory distress syndrome:a multicentre prospective observational study. Lancet Respir Med 8:1201-1208, 2020
3) COVIDSurg Collaborative:Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection:an international cohort study. Lancet 396:27-38, 2020
References_xml – reference: 3) COVIDSurg Collaborative:Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection:an international cohort study. Lancet 396:27-38, 2020
– reference: 6) COVIDSurg Collaborative, GlobalSurg Collaborative:Timing of surgery following SARS-CoV-2 infection:an international prospective cohort study. Anaesthesia 76:748-758, 2021
– reference: 15) Glance LG, Lustik SJ, Hannan EL, et al.:The Surgical Mortality Probability Model:derivation and validation of a simple risk prediction rule for noncardiac surgery. Ann Surg 255:696-702, 2012
– reference: 2) NIHR Global Health Research Unit on Global Surgery-CovidSurg(2020):About CovidSurg.〈https://globalsurg.org/covidsurg/〉(2021.4.1閲覧)
– reference: 9) El-Boghdadly K, Cook TM, Goodacre T, et al.:SARS-CoV-2 infection, COVID-19 and timing of elective surgery:A multidisciplinary consensus statement on behalf of the Association of Anaesthetists, the Centre for Peri-operative Care, the Federation of Surgical Specialty Associations, the Royal College of Anaesthetists and the Royal College of Surgeons of England. Anaesthesia 76:940-946, 2021
– reference: 19) Watson J, Whiting PF, Brush JE:Interpreting a covid-19 test result. BMJ 369:m1808, 2020
– reference: 18) Arevalo-Rodriguez I, Buitrago-Garcia D, Simancas-Racines D, et al.:False-negative results of initial RT-PCR assays for COVID-19:A systematic review. PloS One 15:e0242958, 2020
– reference: 10) Gattinoni L, Chiumello D, Caironi P, et al.:COVID-19 pneumonia:different respiratory treatments for different phenotypes? Intensive Care Med 46:1099-1102, 2020
– reference: 14) Fan E, Beitler JR, Brochard L, et al.:COVID-19-associated acute respiratory distress syndrome:is a different approach to management warranted? Lancet Respir Med 8:816-821, 2020
– reference: 16) Kirmeier E, Eriksson LI, Lewald H, et al.:Post-anaesthesia pulmonary complications after use of muscle relaxants(POPULAR):a multicentre, prospective observational study. Lancet Respir Med 7:129-140, 2019
– reference: 17) 公益社団法人 日本麻酔科学会(2020):新型コロナウイルス感染症(COVID-19)に関する本学会の対応. 〈https://anesth.or.jp/img/upload/ckeditor/files/2004_07_09.pdf〉(2021.4.1閲覧)
– reference: 11) Grasselli G, Tonetti T, Protti A, et al.:Pathophysiology of COVID-19-associated acute respiratory distress syndrome:a multicentre prospective observational study. Lancet Respir Med 8:1201-1208, 2020
– reference: 13) Cummings MJ, Baldwin MR, Abrams D, et al.:Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City:a prospective cohort study. Lancet 395:1763-1770, 2020
– reference: 4) COVIDSurg Collaborative:Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic. Br J Surg 108:88-96, 2021
– reference: 21) Hall J, Myall K, Lam JL, et al.:Identifying patients at risk of post-discharge complications related to COVID-19 infection. Thorax 76:408-411, 2021
– reference: 24) Salluh JIF, Arabi YM, Binnie A:COVID-19 research in critical care:the good, the bad, and the ugly. Intensive Care Med 47:470-472, 2021
– reference: 5) COVIDSurg Collaborative:Elective surgery cancellations due to the COVID-19 pandemic:global predictive modelling to inform surgical recovery plans. Br J Surg 107:1440-1449, 2020
– reference: 7) COVIDSurg Collaborative, GlobalSurg Collaborative:SARS-CoV-2 vaccination modelling for safe surgery to save lives:data from an international prospective cohort study. Br J Surg, 2021;doi:10.1093/bjs/znab101[Epub ahead of print]
– reference: 22) Zarocostas J:How to fight an infodemic. Lancet 395:676, 2020
– reference: 20) Woloshin S, Patel N, Kesselheim AS:False Negative Tests for SARS-CoV-2 Infection - Challenges and Implications. N Engl J Med 383:e38, 2020
– reference: 1) The Center for Systems Science and Engineering(CSSE)at Johns Hopkins University(2020):COVID-19 Dashboard.〈https://gisanddata.maps.arcgis.com/apps/dashboards/bda7594740fd40299423467b48e9ecf6〉(2021.4.1閲覧)
– reference: 8) 厚生労働省:データからわかる─新型コロナウイルス感染症情報─.〈https://covid19.mhlw.go.jp/〉(2021.4.1閲覧)
– reference: 23) Raffle AE, Gill M:Mass screening for asymptomatic SARS-CoV-2 infection. BMJ 373:n1058, 2021
– reference: 12) Tsang JLY, Binnie A, Fowler RA:Twenty articles that critical care clinicians should read about COVID-19. Intensive Care Med 47:337-341, 2021
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[要旨] 新型コロナウイルス感染症(COVID-19)によるパンデミック, それによる医療現場の逼迫の影響は, 麻酔科医を含むあらゆる医師に, 基礎研究のみならず臨床研究・公衆衛生学の重要性を再認識させた. 従来の医学研究は基礎研究に偏重していたため,...
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StartPage 502
SubjectTerms COVID-19
パンデミック
公衆衛生
周術期医学
臨床疫学
Title 危機の時代に立つ,これからの麻酔科医
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