酸化ストレス介在性病変におけるミトコンドリア機能不全の重要性について

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Published in昭和学士会雑誌 Vol. 75; no. 2; pp. 147 - 154
Main Authors 外谷, 衣都子, 柴沼, 質子
Format Journal Article
LanguageJapanese
Published 昭和大学学士会 2015
Online AccessGet full text
ISSN2187-719X
2188-529X
DOI10.14930/jshowaunivsoc.75.147

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Author 外谷, 衣都子
柴沼, 質子
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  fullname: 柴沼, 質子
  organization: 昭和大学薬学部生体分子薬学講座腫瘍細胞生物学部門
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References 8) Mori K, Shibanuma M, Nose K. Invasive potential induced under long-term oxidative stress in mammary epithelial cells. Cancer Res. 2004;64:7464-7472.
11) Gao W, Xu K, Li P, et al. Functional roles of superoxide and hydrogen peroxide generated by mitochondrial DNA mutations in regulation tumorigenicity of HepG2 cells. Cell Biochem Funct. 2011;29:400-407.
7) Shibanuma M, Ishikawa F, Kobayashi M, et al. Critical roles of the cAMP-responsive element-binding protein-mediated pathway in disorganized epithelial phenotypes caused by mitochondrial dysfunction. Cancer Sci. 2012;103:1803-1810.
2) Ralph SJ, Rodriguez-Enriquez S, Neuzil J, et al. The causes of cancer revisited: “Mitochondrial malignancy” and ROS-induced oncogenic transformation-Why mitochondria are targets for cancer therapy. Mol Aspects Med. 2010;31:145-170.
10) Copanaki E, Schurmann T, Eckert A, et al. The amyloid precursor protein potentiates CHOP induction and cell death in response to ER Ca2+ depletion. Biochim Biophys Acta. 2007;1773:157-165.
4) Lee H-C, Wei Y-H. Mitochondrial DNA instability and metabolic shift in human cancers. Int J Mol Sci. 2009;10:674-701.
3) Chatterjee A, Mambo E, Sidransky D. Mitochondrial DNA mutations in human cancer. Oncogene. 2006;35:4663-4674.
6) Ishikawa F, Akimoto T, Yamamoto H, et al. Gene expression profiling identifies a role for CHOP-10 during inhibition of the mitochondrial respiratory chain. J Biochem. 2009;146:123-132.
9) Arnould T, Vankoningsloo S, Renard P, et al. CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation. EMBO J. 2002;21:53-63.
1) Van Houten B, Woshner V, Santos JH. Role of mitochondrial DNA in toxic responses to oxidative stress. DNA Repair (Amst). 2006;5:145-152.
5) Shibanuma M, Inoue A, Ushida K, et al. Importance of mitochondrial dysfunction in oxidative stress responses: A comparative study of gene expression profiles. Free Radic Res. 2011;45:672-680.
References_xml – reference: 1) Van Houten B, Woshner V, Santos JH. Role of mitochondrial DNA in toxic responses to oxidative stress. DNA Repair (Amst). 2006;5:145-152.
– reference: 10) Copanaki E, Schurmann T, Eckert A, et al. The amyloid precursor protein potentiates CHOP induction and cell death in response to ER Ca2+ depletion. Biochim Biophys Acta. 2007;1773:157-165.
– reference: 8) Mori K, Shibanuma M, Nose K. Invasive potential induced under long-term oxidative stress in mammary epithelial cells. Cancer Res. 2004;64:7464-7472.
– reference: 6) Ishikawa F, Akimoto T, Yamamoto H, et al. Gene expression profiling identifies a role for CHOP-10 during inhibition of the mitochondrial respiratory chain. J Biochem. 2009;146:123-132.
– reference: 7) Shibanuma M, Ishikawa F, Kobayashi M, et al. Critical roles of the cAMP-responsive element-binding protein-mediated pathway in disorganized epithelial phenotypes caused by mitochondrial dysfunction. Cancer Sci. 2012;103:1803-1810.
– reference: 2) Ralph SJ, Rodriguez-Enriquez S, Neuzil J, et al. The causes of cancer revisited: “Mitochondrial malignancy” and ROS-induced oncogenic transformation-Why mitochondria are targets for cancer therapy. Mol Aspects Med. 2010;31:145-170.
– reference: 4) Lee H-C, Wei Y-H. Mitochondrial DNA instability and metabolic shift in human cancers. Int J Mol Sci. 2009;10:674-701.
– reference: 9) Arnould T, Vankoningsloo S, Renard P, et al. CREB activation induced by mitochondrial dysfunction is a new signaling pathway that impairs cell proliferation. EMBO J. 2002;21:53-63.
– reference: 11) Gao W, Xu K, Li P, et al. Functional roles of superoxide and hydrogen peroxide generated by mitochondrial DNA mutations in regulation tumorigenicity of HepG2 cells. Cell Biochem Funct. 2011;29:400-407.
– reference: 3) Chatterjee A, Mambo E, Sidransky D. Mitochondrial DNA mutations in human cancer. Oncogene. 2006;35:4663-4674.
– reference: 5) Shibanuma M, Inoue A, Ushida K, et al. Importance of mitochondrial dysfunction in oxidative stress responses: A comparative study of gene expression profiles. Free Radic Res. 2011;45:672-680.
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Title 酸化ストレス介在性病変におけるミトコンドリア機能不全の重要性について
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ispartofPNX 昭和学士会雑誌, 2015, Vol.75(2), pp.147-154
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