心血管モデルを用いたWave-intensityの検討

• Published in: Transactions of Japanese Society for Medical and Biological Engineering Vol. 54Annual; no. 27PM-Abstract; p. S213
• Main Authors: 仁木, 清美, 赤間, 祐介, 大竹, 裕志, 菅原, 基晃, 萱沼, 大, 竹下, 和慶
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本生体医工学会 2016; Japanese Society for Medical and Biological Engineering
• ISSN: 1347-443X; 1881-4379
• DOI: 10.11239/jsmbe.54Annual.S213

[Purpose] Wave-Intensity (WI) is one of the useful hemodynamic indices of the cardiovascular system. However, effects of vascular stiffness on WI waveform are not well known. In this study, we developed a cardiovascular model that includes an elastic tube as a model of a vessel, and measured WI of the elastic tube. [Methods] We made the cardiovascular model composed of pulsatile pump and circulation circuit. The model of elastic vessels were prepared using styrene-based elastomer material (Aronkasei Co., LTD), which were putted in the circulation circuit. We measured the blood vessel stiffness β(β=ln(Ps/Pd)/[(Ds-Dd)/Dd])and WI (WI=(dP/dt)(dU/dt)) using the ultrasonic diagnostic apparatus. [Results] We were able to measure the blood pressure waveform and blood flow velocity waveform. The calculated β was 46.9 and W1 is 1990mmHg×m/s3, which were far from human data (β was higher and W1 was lower than healthy subjects). [Conclusion] Lower β vessel model required to make biological model.