Catecholamine-induced myocardial fibrosis and oxidative stress is attenuated by Terminalia arjuna (Roxb.)

• Published in: Journal of pharmacy and pharmacology Vol. 61; no. 11; p. 1529
• Main Authors: Kumar, Santosh, Enjamoori, Rajesh, Jaiswal, Amardeep, Ray, Ruma, Seth, Sandeep, Maulik, Subir Kumar
• Format: Journal Article
• Language: English
• Published: England 01.11.2009
• Subjects: Adrenergic beta-Agonists; Animals; Antioxidants - pharmacology; Captopril - pharmacology; Cardiomegaly - drug therapy; Fibrosis - chemically induced; Fibrosis - prevention & control; Heart - drug effects; Isoproterenol - pharmacology; Male; Myocardium - pathology; Organ Size; Oxidative Stress - drug effects; Peptidyl-Dipeptidase A; Phytotherapy; Plant Bark; Plant Extracts - pharmacology; Plant Stems; Rats; Rats, Wistar; Terminalia

Myocardial fibrosis and oxidative stress accompany a number of cardiac disorders such as hypertrophic cardiomyopathy, hypertensive heart disease and cardiac failure. Stem bark of Terminalia arjuna has been advocated for cardiac ailments. The present study evaluated the effects of T. arjuna bark extr...