Intranasal Sendai virus‐based SARS‐CoV‐2 vaccine using a mouse model

• Published in: Genes to cells : devoted to molecular & cellular mechanisms Vol. 28; no. 1; pp. 29 - 41
• Main Authors: Morimoto, Satoru, Saeki, Koichi, Takeshita, Masaru, Hirano, Kunio, Shirakawa, Mariko, Yamada, Yumiko, Nakamura, Shiho, Ozawa, Fumiko, Okano, Hideyuki
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.01.2023
• Subjects: Alveoli; Animals; Antibodies, Viral; Bronchus; Coronaviruses; COVID-19; COVID-19 - prevention & control; COVID-19 Vaccines; Disease Models, Animal; Immunization; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; intranasal vaccine; Lavage; Mice; neutralizing antibodies; SARS-CoV-2; Sendai virus; Sendai virus - genetics; Severe acute respiratory syndrome coronavirus 2; Spike protein; Trimers; Vaccines; Viruses; intranasal vaccine; neutralizing antibodies; SARS-CoV-2; Sendai virus

The coronavirus disease 2019 (COVID‐19) epidemic remains worldwide. The usefulness of the intranasal vaccine and boost immunization against severe acute respiratory syndrome‐related coronavirus (SARS‐CoV‐2) has recently received much attention. We developed an intranasal SARS‐CoV‐2 vaccine by loadin...