Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin - ABE, AKIHISA; KOKUBA, HIROKO (Oncology reports, 2013)
Keywords: Apoptosis; Apoptosis - drug effects; Apoptosis - genetics; Asthma; Autophagy; Autophagy - drug effects; Brain cancer; Brain Neoplasms - drug therapy; Brain Neoplasms - metabolism; Brain Neoplasms - pathology; Cancer therapies; Cell cycle; Cell Line, Tumor; Chemotherapy; Cytotoxicity; Down-Regulation; Gene Expression Regulation, Neoplastic - drug effects; Glioma; Glioma - drug therapy; Glioma - genetics; Glioma - pathology; Harmine - analogs & derivatives; Harmine - pharmacology; harmol; Herbal medicine; Homeostasis; Humans; Inhibitor of Apoptosis Proteins - genetics; Inhibitor of Apoptosis Proteins - metabolism; Kinases; mammalian target of rapamycin pathway; Medical prognosis; Phosphorylation; Proteins; Proto-Oncogene Proteins c-akt - genetics; Proto-Oncogene Proteins c-akt - metabolism; RNA, Small Interfering; Signal Transduction; Studies; survivin; TOR Serine-Threonine Kinases - metabolism; United States--US; Japan