Studies on Aldosterone RIA Kit Using Two Antibody Method

Two antibody method of aldosterone RIA kit was investigated. This kit was measured directly without extracting the aldosterone. On fundamental studies, stability of standard curve, reproductivity, recovery test and dillution test were obtained good results. On clinical studies, the diurnal variation...

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Bibliographic Details
Published inRADIOISOTOPES Vol. 37; no. 10; pp. 576 - 579
Main Authors SATOH, Shigekiyo, Sakai, Rinko, KOBAYASHI, Midori
Format Journal Article
LanguageJapanese
Published Japan Japan Radioisotope Association 01.10.1988
Subjects
Adrenocorticotropic Hormone - blood
Adult
Aged
aldosterone
Aldosterone - analysis
Aldosterone - blood
Aldosterone - urine
Child
Circadian Rhythm
diurnal variation
Humans
Hydrocortisone - blood
iodine-125
radioimmunoassay
Radioimmunoassay - standards
Reagent Kits, Diagnostic - standards
Reference Values
two antibody method
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Summary:Two antibody method of aldosterone RIA kit was investigated. This kit was measured directly without extracting the aldosterone. On fundamental studies, stability of standard curve, reproductivity, recovery test and dillution test were obtained good results. On clinical studies, the diurnal variation of serum aldosterone concentration in normal child and adult was correlated well to that of concentration of cortisol and ACTH. The concentration of three hormones was the highest in the early morning and it was the lowest in midnight.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0033-8303
1884-4111
DOI:10.3769/radioisotopes.37.10_576