Clinical study of tazobactam/piperacillin

We evaluated the clinical efficacy and safety of tazobactam/piperacillin (TAZ/PIPC), a drug combining a β-lactamase inhibitor and penicillin. TAZ/PIPC was administrated to 11 patients with infections. The patients received the drug intravenously for 4 to 14 days at a dose of 1.25-5.0 g/day. Clinical...

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Published inCHEMOTHERAPY Vol. 42; no. Supplement2; pp. 710 - 712
Main Authors Wada, Kouichi, Sega, Hiroyuki, Yoshikawa, Hiroko, Tsukada, Hiroki, Arakawa, Masaaki
Format Journal Article
LanguageEnglish
Japanese
Published Japanese Society of Chemotherapy 1994
Subjects
Tazobactam/Piperacillin
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Abstract We evaluated the clinical efficacy and safety of tazobactam/piperacillin (TAZ/PIPC), a drug combining a β-lactamase inhibitor and penicillin. TAZ/PIPC was administrated to 11 patients with infections. The patients received the drug intravenously for 4 to 14 days at a dose of 1.25-5.0 g/day. Clinical effects were good in 10 and unknown in 1. No side effects were noticed. As abnormal laboratory findings, elevations of GOT and GPT were observed in two cases.
AbstractList We evaluated the clinical efficacy and safety of tazobactam/piperacillin (TAZ/PIPC), a drug combining a β-lactamase inhibitor and penicillin. TAZ/PIPC was administrated to 11 patients with infections. The patients received the drug intravenously for 4 to 14 days at a dose of 1.25-5.0 g/day. Clinical effects were good in 10 and unknown in 1. No side effects were noticed. As abnormal laboratory findings, elevations of GOT and GPT were observed in two cases.
Author Sega, Hiroyuki
Yoshikawa, Hiroko
Wada, Kouichi
Tsukada, Hiroki
Arakawa, Masaaki
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  organization: Department of Medicine (II), Niigata University School of Medicine
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  fullname: Sega, Hiroyuki
  organization: Department of Medicine (II), Niigata University School of Medicine
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  fullname: Yoshikawa, Hiroko
  organization: Department of Medicine (II), Niigata University School of Medicine
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  fullname: Tsukada, Hiroki
  organization: Department of Medicine (II), Niigata University School of Medicine
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  fullname: Arakawa, Masaaki
  organization: Department of Medicine (II), Niigata University School of Medicine
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References 1) 武部和夫, 松本慶蔵: 第40回日本化学療法学会東日本支部総会, 新薬シンポジウム. Tazobactam/Piperacillin (TAZ/PIPC, YP-14), 青森, 1993
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Title Clinical study of tazobactam/piperacillin
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