ACUTE, SUBACUTE AND CHRONIC TOXICITY STUDIES OF SULTAMICILLIN

Acute, subacute and chronic toxicities of sultamicillin (SBTPC), a mutual prodrug of sulbactam and ampicillin were evaluated in Sprague-Dawley rats or ICR mice. The acute oral LD50 of SBTPC were estimated to be greater than 10000 mg/kg in rats and mice. In the subacute oral toxicity test, all rats t...

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Bibliographic Details
Published inCHEMOTHERAPY Vol. 33; no. Supplement2; pp. 102 - 111
Main Authors TACHIBANA, MASAKATSU, NABATA, HIROSHI, IIJIMA, MORITAKE, OHTSUKI, ISAO
Format Journal Article
LanguageJapanese
Published Japanese Society of Chemotherapy 1985
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