アルツハイマー病の新薬研究
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| Published in | 薬局薬学 Vol. 16; no. 2; pp. 101 - 103 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Japanese |
| Published |
一般社団法人 日本薬局学会
2024
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 1884-3077 2434-3242 |
| DOI | 10.32160/yakkyoku.ra.2024-4000 |
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| Author | 森, 啓 |
|---|---|
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| Copyright | 2024 一般社団法人 日本薬局学会 |
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| DOI | 10.32160/yakkyoku.ra.2024-4000 |
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| References | 4） Jack CR Jr., Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, Petersen RC, Trojanowski JQ: Hypothetical model of dynamic biomarkers of the alzheimer’s pathological cascade. Lancet Neurol 2010; 9: 119–128. 1） Fortea J, Pegueroles J, Alcolea D, Belbin O, Dols-Icardo O, Vaqué-Alcázar L, Videla L, Gispert JD, Suárez-Calvet M, Johnson SC, Sperling R, Bejanin A, Lleó A, Montal V: APOE4 homozygozity represents a distinct genetic form of Alzheimer’s disease. Nat Med 2024; 30: 1284–1291. 2） Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, Bergstrom M, Savitcheva I, Huang GF, Estrada S, Ausen B, Debnath ML, Barletta J, Price JC, Sandell J, Lopresti BJ, Wall A, Koivisto P, Antoni G, Mathis CA, Langstrom B: Imaging brain amyloid in alzheimer’s disease with pittsburgh compound-b. Ann Neurol 2004; 55: 306–319. 3） Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR, Jagust W, Liu E, Morris JC, Petersen RC, Saykin AJ, Schmidt ME, Shaw L, Siuciak JA, Soares H, Toga AW, Trojanowski JQ: The alzheimer’s disease neuroimaging initiative: a review of papers published since its inception. Alzheimers Dement 2012; 8(Suppl): S1–S68. 8） Nicoll JAR, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO: Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med 2003; 9: 448–452. 6） Hardy J, Selkoe DJ: The amyloid hypothesis of alzheimer’s disease: Progress and problems on the road to therapeutics. Science 2002; 297: 353–356. 7） Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Liao Z, Lieberburg I, Motter R, Mutter L, Soriano F, Shopp G, Vasquez N, Vandevert C, Walker S, Wogulis M, Yednock T, Games D, Seubert P: Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 1999; 400: 173–177. 5） Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, Aisen PS, Ghetti B, Klunk WE, McDade E, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Schofield PR, Sperling RA, Salloway S, Morris JC: Clinical and biomarker changes in dominantly inherited alzheimer’s disease. N Engl J Med 2012; 367: 795–804. |
| References_xml | – reference: 2） Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, Bergstrom M, Savitcheva I, Huang GF, Estrada S, Ausen B, Debnath ML, Barletta J, Price JC, Sandell J, Lopresti BJ, Wall A, Koivisto P, Antoni G, Mathis CA, Langstrom B: Imaging brain amyloid in alzheimer’s disease with pittsburgh compound-b. Ann Neurol 2004; 55: 306–319. – reference: 6） Hardy J, Selkoe DJ: The amyloid hypothesis of alzheimer’s disease: Progress and problems on the road to therapeutics. Science 2002; 297: 353–356. – reference: 8） Nicoll JAR, Wilkinson D, Holmes C, Steart P, Markham H, Weller RO: Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med 2003; 9: 448–452. – reference: 7） Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Liao Z, Lieberburg I, Motter R, Mutter L, Soriano F, Shopp G, Vasquez N, Vandevert C, Walker S, Wogulis M, Yednock T, Games D, Seubert P: Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 1999; 400: 173–177. – reference: 4） Jack CR Jr., Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, Petersen RC, Trojanowski JQ: Hypothetical model of dynamic biomarkers of the alzheimer’s pathological cascade. Lancet Neurol 2010; 9: 119–128. – reference: 3） Weiner MW, Veitch DP, Aisen PS, Beckett LA, Cairns NJ, Green RC, Harvey D, Jack CR, Jagust W, Liu E, Morris JC, Petersen RC, Saykin AJ, Schmidt ME, Shaw L, Siuciak JA, Soares H, Toga AW, Trojanowski JQ: The alzheimer’s disease neuroimaging initiative: a review of papers published since its inception. Alzheimers Dement 2012; 8(Suppl): S1–S68. – reference: 5） Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, Aisen PS, Ghetti B, Klunk WE, McDade E, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Schofield PR, Sperling RA, Salloway S, Morris JC: Clinical and biomarker changes in dominantly inherited alzheimer’s disease. N Engl J Med 2012; 367: 795–804. – reference: 1） Fortea J, Pegueroles J, Alcolea D, Belbin O, Dols-Icardo O, Vaqué-Alcázar L, Videla L, Gispert JD, Suárez-Calvet M, Johnson SC, Sperling R, Bejanin A, Lleó A, Montal V: APOE4 homozygozity represents a distinct genetic form of Alzheimer’s disease. Nat Med 2024; 30: 1284–1291. |
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| Title | アルツハイマー病の新薬研究 |
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