硬口蓋に生じたglomus腫瘍の1例

Glomus tumor is a benign tumor derived from glomus cells found in the arteriovenous anastomosis in the vascular plexus of the skin and nail bed. Typically, it is a reddish purple and painful tumor with a predilection site for arising in the extremities, especially the nail bed. There are a few repor...

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Published in日本口腔外科学会雑誌 Vol. 65; no. 12; pp. 792 - 796
Main Authors 堤, 泰彦, 弘部, 悠, 山本, 学, 町田, 好聡, 浅田, 泰幸, 家森, 正志
Format Journal Article
LanguageJapanese
Published 社団法人 日本口腔外科学会 20.12.2019
Subjects
glomus腫瘍
硬口蓋
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.65.792

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Abstract Glomus tumor is a benign tumor derived from glomus cells found in the arteriovenous anastomosis in the vascular plexus of the skin and nail bed. Typically, it is a reddish purple and painful tumor with a predilection site for arising in the extremities, especially the nail bed. There are a few reports of the tumor arising in the oral region as well. Here, we report a case of a glomus tumor that developed in the palate.　The patient was a 69-year-old woman who noticed a tumor in the left side of the palate around 2012, but left it untreated. In 2014, the mass gradually increased, and maladaptation of the denture occurred as a result of which she visited a local dentist. The patient was referred to our hospital for further examination.　An elastic soft mass approximately 20 mm in diameter was discovered in the hard palate in the left maxillary molar region. Biopsy results led to the diagnosis of a glomus tumor. In December 2014, the palatal tumor was resected with the patient under general anesthesia. Five years after operation, no recurrence tendency has been noted, and the postoperative course is favorable.
AbstractList Glomus tumor is a benign tumor derived from glomus cells found in the arteriovenous anastomosis in the vascular plexus of the skin and nail bed. Typically, it is a reddish purple and painful tumor with a predilection site for arising in the extremities, especially the nail bed. There are a few reports of the tumor arising in the oral region as well. Here, we report a case of a glomus tumor that developed in the palate.　The patient was a 69-year-old woman who noticed a tumor in the left side of the palate around 2012, but left it untreated. In 2014, the mass gradually increased, and maladaptation of the denture occurred as a result of which she visited a local dentist. The patient was referred to our hospital for further examination.　An elastic soft mass approximately 20 mm in diameter was discovered in the hard palate in the left maxillary molar region. Biopsy results led to the diagnosis of a glomus tumor. In December 2014, the palatal tumor was resected with the patient under general anesthesia. Five years after operation, no recurrence tendency has been noted, and the postoperative course is favorable.
Author 浅田, 泰幸
家森, 正志
町田, 好聡
山本, 学
弘部, 悠
堤, 泰彦
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References 2) 前田由紀子， 入江太郎， 他：口蓋に発生したグロームス腫瘍の一例．昭和歯会誌 25: 6-10, 2005.
19) Moody GH, Myskow M, et al : Glomus tumor of lip. A case report and immunohistochemical study. Oral Surg Oral Med Oral Pathol 62: 312-318, 1986.
37) 太田貴久， 鷲見成起， 他：上唇正中部に生じたGlomangiomyomaの1例．口腔腫瘍 26: 25-30, 2014.
8) Grande R and D’Angelo E : Un tumore glomico del plato duro. Arch Ital Laringol 70: 89, 1962.
27) Rallis G, Komis C, et al : Glomus tumor: a rare location in the upper lip. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98: 327-336, 2004.
11) Sidhu SS and Subherwal GL : Glomus tumor of palate. Indian Dent Assoc 39: 167-168, 1967.
35) 岸本恵美， 土屋知子， 他：グロムス腫瘍−5例の報告と当科経験5例を合わせた免疫組織化学的検討−．皮膚臨床 47: 207-213, 2005.
33) Kurohara K, Michi Y, et al : The glomus tumor resorbed bone and teeth in the mandible : a case report. Head & Face Medicine 14, 2018.　at:https://head-face-med.biomedcentral.com/articles/10.1186/s13005-018-0175-3 Accessed May 14, 2019.
24) Sakashita H, Miyata M, et al : Glomus tumor in the upper lip: a case report. Int J Oral Maxillofac Sur 26: 301-302, 1997.
31) Derand P III, Warfvinge G, et al : Glomangioma : A case Presentation. J Oral Maxillofac Surg 68: 204-207, 2010.
18) Ficarra G, Merrell PW, et al : Intraoral solitary glomus tumor (glomngioma) case report and literature review. Oral Surg Oral Med Oral Pathol 62: 306-311, 1986.
6) King ES : Glomus tumor. Aust N Z J Surg 23: 280-295, 1954.
15) Sato M, Shirasuna K, et al : Fine structure of a glomus tumor of the tongue and expression of C type virus in its tumor cells. Int J Oral Surg 8: 199-204, 1979.
30) Boros AL, Davis JP, et al : Glomus tumor: report of a rare case affecting the Oral cavity and review of the literature. J Oral Maxillofac Surg 68: 2329-2334, 2010.
10) Harris R and Griffin CJ : Glomus tumor of the periodontal tissues. Aust Dent J 10: 33-37, 1965.
1) Masson P : Le glomus neuromyo-aryerial des regions tactiles et ses tumeurs. Lyon Chir 21: 257-280, 1924.
26) Kessaris P, Klimis T, et al : Glomus tumor of the hard palate : case report and review. Br J Oral Maxillofac Surg 39: 478-479, 2001.
14) Charles NC : Multiple glomus tumors of the face and eyelid. Arch Ophthalmol 94: 1283-1285, 1976.
25) Yu HJ, Kwon SJ, et al : Localized multiple glomus tumors of the face and oral mucosa. J Dermatol 27: 211-213, 2000.
5) Von Langer R : Gromustumor am harten Gaumen. Wein Med Wochenschr 99: 67, 1949.
36) Folpe AL, Fanburg-Smith JC, et al : Atypical and malignant glomus tumors : Analysis of 52 cases, with a proposal for the reclassification of glomus tumors. Am J Surg Pathol 25: 1-12, 2001.
28) Quesada R, Gonzales-Lgunas J, et al : Aggressive glomus tumor of the tongue : report of a case. Med Oral 9: 350-354, 2004.
34) 徐　信夫， 草壁秀成， 他：グロムス腫瘍−その3症例と免疫染色化学的検討−．皮膚 35: 361-367, 1993.
23) Kusama K, Kidokoro Y, et al : Glomus tumor of the upper lip. J Nihon Univ Sch Dent 37: 97-101, 1995.
13) 鈴木慶二， 堀　貞夫， 他：口蓋に発生したglomus tumorの1症例 光顕的ならびに電顕的観察．北関東医 24: 223-227, 1974.
4) 清水　宏：新しい皮膚科学．第2版， 中山書店， 東京， 2011, 357-376 頁
7) Kirschner H and Strassburg M : Ein am zhanlosen Alveolarfortsatz des Unterkiefers lokalisierter Glomustumor. Dtsch Zahnarzl Z 17: 912, 1962.
16) Tajima Y, Weaters DR, et al : Glomus tumor (glomangioma) of the tongue : a light and electron microscopic study. Oral Surg Oral Med Oral Pathol 52: 288-293, 1981.
9) Frankel VG : Auftreten eines leimyofibromangioms (Glomangioms) im Wangen-und Jochbogenbereich. Dtsh Zahnartzl Zschr 20: 168, 1965.
20) Stajcic Z and Bojic P : Intraoral glomus tumour. A case report. J Craniomaxillofac Surg 15: 376-378, 1987.
12) 冨田喜内， 河正正昭， 他：硬口蓋に発生したGlomus tumorの1例− 特に電顕的所見について−．日口外誌 18: 681, 1972.
29) Lanza A, Moscariello A, et al : Glomus tumor of the lower lip. A case report. Minerva Stomatol 54: 687-90, 2005.
3) Enzinger FM and Weiss SW : Enzinger and Weiss’s soft tissue tumor 6th Ed. Elsevier/Saunders， Philadelphia, 2014, p581-595.
32) 野上晋之介， 山本哲彰， 他：上唇に生じたglomus腫瘍の1例．日口外誌 58: 429-433, 2012.
22) Geraghty JM, Thomas RW, et al : Glomus tumour of the palate : case report and review of the literature. Br J Oral Maxillofac Surg 30: 398-400, 1992.
17) Saku T, Okabe H, et al : Glomus tumor of the cheek : an immunohistochemical demonstration of actin and myosin. Oral Surg Oral Med Oral Pathol 60: 65-71, 1985.
21) 常葉伸也， 佐藤　篤， 他：下顎歯肉に発生したグロムス腫瘍の1例. 日口外誌 36: 2295-2299, 1990.
References_xml – reference: 14) Charles NC : Multiple glomus tumors of the face and eyelid. Arch Ophthalmol 94: 1283-1285, 1976.
– reference: 25) Yu HJ, Kwon SJ, et al : Localized multiple glomus tumors of the face and oral mucosa. J Dermatol 27: 211-213, 2000.
– reference: 31) Derand P III, Warfvinge G, et al : Glomangioma : A case Presentation. J Oral Maxillofac Surg 68: 204-207, 2010.
– reference: 34) 徐　信夫， 草壁秀成， 他：グロムス腫瘍−その3症例と免疫染色化学的検討−．皮膚 35: 361-367, 1993.
– reference: 10) Harris R and Griffin CJ : Glomus tumor of the periodontal tissues. Aust Dent J 10: 33-37, 1965.
– reference: 20) Stajcic Z and Bojic P : Intraoral glomus tumour. A case report. J Craniomaxillofac Surg 15: 376-378, 1987.
– reference: 4) 清水　宏：新しい皮膚科学．第2版， 中山書店， 東京， 2011, 357-376 頁．
– reference: 2) 前田由紀子， 入江太郎， 他：口蓋に発生したグロームス腫瘍の一例．昭和歯会誌 25: 6-10, 2005.
– reference: 22) Geraghty JM, Thomas RW, et al : Glomus tumour of the palate : case report and review of the literature. Br J Oral Maxillofac Surg 30: 398-400, 1992.
– reference: 16) Tajima Y, Weaters DR, et al : Glomus tumor (glomangioma) of the tongue : a light and electron microscopic study. Oral Surg Oral Med Oral Pathol 52: 288-293, 1981.
– reference: 17) Saku T, Okabe H, et al : Glomus tumor of the cheek : an immunohistochemical demonstration of actin and myosin. Oral Surg Oral Med Oral Pathol 60: 65-71, 1985.
– reference: 6) King ES : Glomus tumor. Aust N Z J Surg 23: 280-295, 1954.
– reference: 26) Kessaris P, Klimis T, et al : Glomus tumor of the hard palate : case report and review. Br J Oral Maxillofac Surg 39: 478-479, 2001.
– reference: 24) Sakashita H, Miyata M, et al : Glomus tumor in the upper lip: a case report. Int J Oral Maxillofac Sur 26: 301-302, 1997.
– reference: 18) Ficarra G, Merrell PW, et al : Intraoral solitary glomus tumor (glomngioma) case report and literature review. Oral Surg Oral Med Oral Pathol 62: 306-311, 1986.
– reference: 36) Folpe AL, Fanburg-Smith JC, et al : Atypical and malignant glomus tumors : Analysis of 52 cases, with a proposal for the reclassification of glomus tumors. Am J Surg Pathol 25: 1-12, 2001.
– reference: 30) Boros AL, Davis JP, et al : Glomus tumor: report of a rare case affecting the Oral cavity and review of the literature. J Oral Maxillofac Surg 68: 2329-2334, 2010.
– reference: 5) Von Langer R : Gromustumor am harten Gaumen. Wein Med Wochenschr 99: 67, 1949.
– reference: 19) Moody GH, Myskow M, et al : Glomus tumor of lip. A case report and immunohistochemical study. Oral Surg Oral Med Oral Pathol 62: 312-318, 1986.
– reference: 27) Rallis G, Komis C, et al : Glomus tumor: a rare location in the upper lip. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 98: 327-336, 2004.
– reference: 21) 常葉伸也， 佐藤　篤， 他：下顎歯肉に発生したグロムス腫瘍の1例. 日口外誌 36: 2295-2299, 1990.
– reference: 9) Frankel VG : Auftreten eines leimyofibromangioms (Glomangioms) im Wangen-und Jochbogenbereich. Dtsh Zahnartzl Zschr 20: 168, 1965.
– reference: 29) Lanza A, Moscariello A, et al : Glomus tumor of the lower lip. A case report. Minerva Stomatol 54: 687-90, 2005.
– reference: 13) 鈴木慶二， 堀　貞夫， 他：口蓋に発生したglomus tumorの1症例 光顕的ならびに電顕的観察．北関東医 24: 223-227, 1974.
– reference: 12) 冨田喜内， 河正正昭， 他：硬口蓋に発生したGlomus tumorの1例− 特に電顕的所見について−．日口外誌 18: 681, 1972.
– reference: 35) 岸本恵美， 土屋知子， 他：グロムス腫瘍−5例の報告と当科経験5例を合わせた免疫組織化学的検討−．皮膚臨床 47: 207-213, 2005.
– reference: 15) Sato M, Shirasuna K, et al : Fine structure of a glomus tumor of the tongue and expression of C type virus in its tumor cells. Int J Oral Surg 8: 199-204, 1979.
– reference: 7) Kirschner H and Strassburg M : Ein am zhanlosen Alveolarfortsatz des Unterkiefers lokalisierter Glomustumor. Dtsch Zahnarzl Z 17: 912, 1962.
– reference: 8) Grande R and D’Angelo E : Un tumore glomico del plato duro. Arch Ital Laringol 70: 89, 1962.
– reference: 11) Sidhu SS and Subherwal GL : Glomus tumor of palate. Indian Dent Assoc 39: 167-168, 1967.
– reference: 23) Kusama K, Kidokoro Y, et al : Glomus tumor of the upper lip. J Nihon Univ Sch Dent 37: 97-101, 1995.
– reference: 33) Kurohara K, Michi Y, et al : The glomus tumor resorbed bone and teeth in the mandible : a case report. Head & Face Medicine 14, 2018.　at:https://head-face-med.biomedcentral.com/articles/10.1186/s13005-018-0175-3 Accessed May 14, 2019.
– reference: 32) 野上晋之介， 山本哲彰， 他：上唇に生じたglomus腫瘍の1例．日口外誌 58: 429-433, 2012.
– reference: 37) 太田貴久， 鷲見成起， 他：上唇正中部に生じたGlomangiomyomaの1例．口腔腫瘍 26: 25-30, 2014.
– reference: 28) Quesada R, Gonzales-Lgunas J, et al : Aggressive glomus tumor of the tongue : report of a case. Med Oral 9: 350-354, 2004.
– reference: 3) Enzinger FM and Weiss SW : Enzinger and Weiss’s soft tissue tumor 6th Ed. Elsevier/Saunders， Philadelphia, 2014, p581-595.
– reference: 1) Masson P : Le glomus neuromyo-aryerial des regions tactiles et ses tumeurs. Lyon Chir 21: 257-280, 1924.
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Snippet Glomus tumor is a benign tumor derived from glomus cells found in the arteriovenous anastomosis in the vascular plexus of the skin and nail bed. Typically, it...
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SubjectTerms glomus腫瘍
硬口蓋
Title 硬口蓋に生じたglomus腫瘍の1例
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