肺動脈性肺高血圧症に対するフィンゴリモドの薬効評価

• Published in: 日本薬理学会年会要旨集 p. 1-LBS-18
• Main Authors: 藤原, 萌園, 山村, 彩, 鈴木, 良明, 山村, 寿男
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本薬理学会 2020
• Subjects: smooth muscle

Pulmonary arterial hypertension (PAH) is pathophysiologically characterized by vasoconstriction and vascular remodeling of the pulmonary artery. Pulmonary vascular remodeling is mainly mediated by the enhanced cell proliferation of pulmonary arterial smooth muscle cells (PASMCs). In this study, we e...