肺動脈性肺高血圧症におけるクロライドチャネルClC3の病態生理学的役割の解明

• Published in: 日本薬理学会年会要旨集 p. 1-B-SS03-1
• Main Authors: 天野, 泰樹, 山村, 彩, 藤原, 萌園, 近藤, るびい, 鈴木, 良明, 山村, 寿男
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本薬理学会 2023
• Subjects: Cl- channel; その他

Pulmonary arterial hypertension (PAH) causes chronical increase in pulmonary artery pressure rises due to pulmonary vasoconstriction and vascular remodeling. Although several PAH drugs have been recently developed, no curative treatment has yet been achieved. Sustained elevation of cytosolic Ca2+ co...