下顎歯肉に発生した類基底扁平上皮癌の1例

Basaloid squamous cell carcinoma (BSCC), a variant of squamous cell carcinoma (SCC), is characterized by the growth of basaloid tumor cells. The mandibular gingiva is a rare site of BSCC. We present a case of BSCC of the mandibular gingiva. A 52-year-old woman was referred to our hospital because of...

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Published in日本口腔外科学会雑誌 Vol. 59; no. 6; pp. 422 - 426
Main Authors 鵜沢, 一弘, 丹沢, 秀樹, 中嶋, 大, 椎葉, 正史, 齋藤, 謙悟, 伏見, 一章
Format Journal Article
LanguageJapanese
Published 社団法人 日本口腔外科学会 20.06.2013
Subjects
下顎
予後
転移
類基底扁平上皮癌
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.59.422

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Abstract Basaloid squamous cell carcinoma (BSCC), a variant of squamous cell carcinoma (SCC), is characterized by the growth of basaloid tumor cells. The mandibular gingiva is a rare site of BSCC. We present a case of BSCC of the mandibular gingiva. A 52-year-old woman was referred to our hospital because of pain, swelling, and white lesions of the mandible. The lesion was irregularly shaped with induration and extended bilaterally to the gingiva, oral floor, lower lip, and mental region. Since SCC was suggested by a biopsy, the patient received adjuvant chemotherapy, and surgical excision was performed under general anesthesia. Microscopically, the tumor had two components, i.e., basaloid cells and squamous cells. The basaloid component consisted of small cells arranged in lobules, cords, and solid masses. On the basis of the histopathologic findings, a final diagnosis of BSCC was made. There has been no sign of recurrence for 4 years 9 months since treatment. BSCC has been reported to be more invasive and metastatic than SCC. Thus, long-term and careful follow-up is necessary in the present patient.
AbstractList Basaloid squamous cell carcinoma (BSCC), a variant of squamous cell carcinoma (SCC), is characterized by the growth of basaloid tumor cells. The mandibular gingiva is a rare site of BSCC. We present a case of BSCC of the mandibular gingiva. A 52-year-old woman was referred to our hospital because of pain, swelling, and white lesions of the mandible. The lesion was irregularly shaped with induration and extended bilaterally to the gingiva, oral floor, lower lip, and mental region. Since SCC was suggested by a biopsy, the patient received adjuvant chemotherapy, and surgical excision was performed under general anesthesia. Microscopically, the tumor had two components, i.e., basaloid cells and squamous cells. The basaloid component consisted of small cells arranged in lobules, cords, and solid masses. On the basis of the histopathologic findings, a final diagnosis of BSCC was made. There has been no sign of recurrence for 4 years 9 months since treatment. BSCC has been reported to be more invasive and metastatic than SCC. Thus, long-term and careful follow-up is necessary in the present patient.
Author 鵜沢, 一弘
伏見, 一章
丹沢, 秀樹
椎葉, 正史
齋藤, 謙悟
中嶋, 大
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References 17) 八幡有紀子，徳丸　裕，他：舌に発生したbasaloidsquamous cell carcinomaの1例．耳喉頭頸 78: 229-232, 2006.
25) Luna MA, EI-Nagger A, et al : Basaloid squamous carcinoma of the upper aerodigestive tract clinicopathologic and DNA flow cytometric analysis. Cancer 66: 537-542, 1990.
2) Darier J : Des epitheliomes primitives de la peau. Br J Dermatol Syph 34: 145-149, 1922.
10) 山本一宏，前田秀明：鼻腔類基底細胞癌の1症例．耳喉頭頸 74: 212-215, 2002.
14) 石丸純一，渡邉達也，他：上顎歯肉に発生したbasaloid squamous cell carcinoma の1例．日口外誌50: 542-545, 2004.
5) 平海清一，平塚康之，他：下咽頭類基底細胞癌例．耳鼻臨床 92: 881-884, 1999.
7) 栗原憲二，水関　清，他：下咽頭に発生した類基底細胞癌の1例．耳喉頭頸 72: 39-42, 2000.
3) World Health Organization : Histological Typing of Tumors of the Upper Respiratory Tract and Ear (by Shanmugaratuam K.). 2nd Ed, Springer-Verlag, Berlin, 1991, p31.
21) Ferlito A, Altavilla G, et al : Basaloid squamous cell carcinoma of the larynx and hypopharynx. Ann Otol Rhinol Laryngol 106: 1024-1035, 1997.
26) Ide F, Shimoyama T, et al : Basaloid squamous cell carcinoma of the oral mucosa: a new case and review of 45 cases in the literature. Oral Oncol 38: 120-124, 2002.
4) 有田実織，坂本菜穂子，他：上咽頭原発Basaloidsquamous cell carcinomaの1例．耳鼻と臨 45: 207-210, 1999.
18) 青木将虎，倉富慶太郎，他：舌に生じた外向性類基底細胞癌の1例．日口外誌 53: 662-666, 2007.
13) 堀江理恵，佐藤進一，他：上顎洞原発BasaloidSquamous Cell Carcinoma例．耳鼻臨床 97: 417-421, 2003.
24) Larner JM, Malcolm RH, et al : Radiotherapy for basaloid squamous cell carcinoma of the head and neck. Head Neck 15: 249-252, 1993.
1) Wain SL, Kier R, et al : Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases. Hum Pathol 17: 1158-1166, 1986.
11) 井上さやか，伊藤重人，他：下顎歯肉に発生したbasaloid squamous cell carcinomaの1例． 口科誌52: 195-199, 2003.
16) 伊藤英美，高岡一樹，他：口底に生じたbasaloidsquamous cell carcinomaの1例．日口外誌 52: 19-22, 2006.
23) Banks ER, Frierson HF Jr, et al : Basaloid squamous cell carcinoma of the head and neck. A clinicopathologic and immunohistochemical study of 40 cases. Am J Surg Pathol 16: 939-946, 1992.
15) 津野宏彰，和田重人，他：口底部に発生したbasaloidsquamous cell carcinomaの1例 －Ki-67を用いた免疫組織化学的検索による細胞増殖能の評価－．日口外誌 51: 614-617, 2005.
9) 辻　智子，篠原かおる，他：舌根部類基底細胞癌例．耳鼻臨床 94: 453-463, 2001.
22) Raslan WF, Barnes L, et al : Basaloid squamous cell carcinoma of the head and neck: a clinicopathologic and flow cytometric study of 10 new cases with review of the English literature. Am J Otolaryngol 15: 204-211, 1994.
8) 小西正訓，平　篤史，他：下咽頭類基底細胞扁平上皮癌例．耳鼻臨床 93: 135-142, 2000.
19) 大高隆輝，安部裕介，他：Basaloid squamous cellcarcinomaの2例．耳鼻臨床 101: 943-949, 2008.
6) 後藤　孝，小林吉史，他:上顎洞Basaloid squamouscell carcinoma例. 耳鼻臨床 92: 868-873, 1999.
12) 矢島哲弥，木下靖朗，他：口蓋垂に発生したbasaloidsquamous cell carcinomaの1例．日口外誌 49: 386-389, 2003.
20) 橘　寛彦，松尾　朗，他：舌に発生したBasaloidsquamous cell carcinomaの1例．日口外誌 58: 362-365, 2012.
References_xml – reference: 7) 栗原憲二，水関　清，他：下咽頭に発生した類基底細胞癌の1例．耳喉頭頸 72: 39-42, 2000.
– reference: 13) 堀江理恵，佐藤進一，他：上顎洞原発BasaloidSquamous Cell Carcinoma例．耳鼻臨床 97: 417-421, 2003.
– reference: 11) 井上さやか，伊藤重人，他：下顎歯肉に発生したbasaloid squamous cell carcinomaの1例． 口科誌52: 195-199, 2003.
– reference: 6) 後藤　孝，小林吉史，他:上顎洞Basaloid squamouscell carcinoma例. 耳鼻臨床 92: 868-873, 1999.
– reference: 19) 大高隆輝，安部裕介，他：Basaloid squamous cellcarcinomaの2例．耳鼻臨床 101: 943-949, 2008.
– reference: 4) 有田実織，坂本菜穂子，他：上咽頭原発Basaloidsquamous cell carcinomaの1例．耳鼻と臨 45: 207-210, 1999.
– reference: 20) 橘　寛彦，松尾　朗，他：舌に発生したBasaloidsquamous cell carcinomaの1例．日口外誌 58: 362-365, 2012.
– reference: 3) World Health Organization : Histological Typing of Tumors of the Upper Respiratory Tract and Ear (by Shanmugaratuam K.). 2nd Ed, Springer-Verlag, Berlin, 1991, p31.
– reference: 23) Banks ER, Frierson HF Jr, et al : Basaloid squamous cell carcinoma of the head and neck. A clinicopathologic and immunohistochemical study of 40 cases. Am J Surg Pathol 16: 939-946, 1992.
– reference: 12) 矢島哲弥，木下靖朗，他：口蓋垂に発生したbasaloidsquamous cell carcinomaの1例．日口外誌 49: 386-389, 2003.
– reference: 15) 津野宏彰，和田重人，他：口底部に発生したbasaloidsquamous cell carcinomaの1例 －Ki-67を用いた免疫組織化学的検索による細胞増殖能の評価－．日口外誌 51: 614-617, 2005.
– reference: 14) 石丸純一，渡邉達也，他：上顎歯肉に発生したbasaloid squamous cell carcinoma の1例．日口外誌50: 542-545, 2004.
– reference: 25) Luna MA, EI-Nagger A, et al : Basaloid squamous carcinoma of the upper aerodigestive tract clinicopathologic and DNA flow cytometric analysis. Cancer 66: 537-542, 1990.
– reference: 21) Ferlito A, Altavilla G, et al : Basaloid squamous cell carcinoma of the larynx and hypopharynx. Ann Otol Rhinol Laryngol 106: 1024-1035, 1997.
– reference: 1) Wain SL, Kier R, et al : Basaloid-squamous carcinoma of the tongue, hypopharynx, and larynx: report of 10 cases. Hum Pathol 17: 1158-1166, 1986.
– reference: 10) 山本一宏，前田秀明：鼻腔類基底細胞癌の1症例．耳喉頭頸 74: 212-215, 2002.
– reference: 18) 青木将虎，倉富慶太郎，他：舌に生じた外向性類基底細胞癌の1例．日口外誌 53: 662-666, 2007.
– reference: 8) 小西正訓，平　篤史，他：下咽頭類基底細胞扁平上皮癌例．耳鼻臨床 93: 135-142, 2000.
– reference: 5) 平海清一，平塚康之，他：下咽頭類基底細胞癌例．耳鼻臨床 92: 881-884, 1999.
– reference: 16) 伊藤英美，高岡一樹，他：口底に生じたbasaloidsquamous cell carcinomaの1例．日口外誌 52: 19-22, 2006.
– reference: 26) Ide F, Shimoyama T, et al : Basaloid squamous cell carcinoma of the oral mucosa: a new case and review of 45 cases in the literature. Oral Oncol 38: 120-124, 2002.
– reference: 24) Larner JM, Malcolm RH, et al : Radiotherapy for basaloid squamous cell carcinoma of the head and neck. Head Neck 15: 249-252, 1993.
– reference: 17) 八幡有紀子，徳丸　裕，他：舌に発生したbasaloidsquamous cell carcinomaの1例．耳喉頭頸 78: 229-232, 2006.
– reference: 22) Raslan WF, Barnes L, et al : Basaloid squamous cell carcinoma of the head and neck: a clinicopathologic and flow cytometric study of 10 new cases with review of the English literature. Am J Otolaryngol 15: 204-211, 1994.
– reference: 2) Darier J : Des epitheliomes primitives de la peau. Br J Dermatol Syph 34: 145-149, 1922.
– reference: 9) 辻　智子，篠原かおる，他：舌根部類基底細胞癌例．耳鼻臨床 94: 453-463, 2001.
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Snippet Basaloid squamous cell carcinoma (BSCC), a variant of squamous cell carcinoma (SCC), is characterized by the growth of basaloid tumor cells. The mandibular...
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StartPage 422
SubjectTerms 下顎
予後
転移
類基底扁平上皮癌
Title 下顎歯肉に発生した類基底扁平上皮癌の1例
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