甲状腺転移をきたした下顎歯肉紡錘細胞癌の1例

• Published in: 日本口腔外科学会雑誌 Vol. 64; no. 3; pp. 170 - 174
• Main Authors: 伏見, 千宙, 黒坂, 正生, 菅野, 千敬, 荘司, 洋文, 猪俣, 徹, 吉田, 和正
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 20.03.2018
• Subjects: 下顎歯肉; 甲状腺; 紡錘細胞癌
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.64.170

Spindle cell carcinoma is a tumor histologically characterized by polymorphic cells comprising mainly spindle-shaped cells that proliferate and present with an image reminiscent of sarcoma. Reports of this carcinoma in the oral cavity region are rare, and there have been no reports, either in Japan or in other countries, of metastasis to the thyroid gland. The authors encountered a case in which spindle cell carcinoma recurred after resection and metastasized to the thyroid gland and describe the outcome. The patient was a 76-year-old man with spindle cell carcinoma of the mandibular gingiva who underwent resection of the borders of the mandible, supraomohyoid neck dissection and reconstruction using a free forearm flap. Eleven months later, however, localized recurrence of the carcinoma was seen in the medial pterygoid muscle. The patient underwent surgery again, followed by postoperative radiotherapy alone. Because metastasis to the right lobe of the thyroid gland was observed, however, the patient underwent total thyroidectomy. One year 5 months after surgery, the patient is doing well, with no further recurrence or metastasis.