口腔癌の化学療法中に発症した肺血栓塞栓症の1例

In addition to cancer-bearing status, chemotherapy is one of the moderate risk factors for the development of thromboembolism. However, there are few reports about it for oral cancer. Here, we report a case of pulmonary thromboembolism (PTE) that developed during chemotherapy for oral cancer. The pa...

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Published in日本口腔外科学会雑誌 Vol. 68; no. 4; pp. 193 - 200
Main Authors 柴田, 茜, 志茂, 剛, 岸本, 晃治, 國定, 勇希, 目瀬, 浩, 佐々木, 朗
Format Journal Article
LanguageJapanese
Published 公益社団法人 日本口腔外科学会 20.04.2022
Subjects
化学療法
口腔癌
肺血栓塞栓症
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Abstract In addition to cancer-bearing status, chemotherapy is one of the moderate risk factors for the development of thromboembolism. However, there are few reports about it for oral cancer. Here, we report a case of pulmonary thromboembolism (PTE) that developed during chemotherapy for oral cancer. The patient was a 59-year-old man with left maxillary gingival cancer (T2N2bM0, Stage ⅣA). He complained of chest pain and dyspnea on the third day of the first course of TPF (docetaxel, cisplatin, 5-FU), which was performed as preoperative chemotherapy. Therefore, we performed an electrocardiogram and contrast-enhanced CT imaging. ST elevation, tachycardia and atrial fibrillation were observed on the electrocardiogram. PTE was also observed in his left lung in CT images. We immediately started the administration of β -blocker and anticoagulant therapies. After that the patient’s subjective symptoms disappeared and the electrocardiogram showed stability two days later. Therefore, chemotherapy was continued and completed. After three weeks, a left maxillary partial resection and left radical neck dissection were performed. Following the operation, there have been no PTE symptoms and he is making good progress.
AbstractList In addition to cancer-bearing status, chemotherapy is one of the moderate risk factors for the development of thromboembolism. However, there are few reports about it for oral cancer. Here, we report a case of pulmonary thromboembolism (PTE) that developed during chemotherapy for oral cancer. The patient was a 59-year-old man with left maxillary gingival cancer (T2N2bM0, Stage ⅣA). He complained of chest pain and dyspnea on the third day of the first course of TPF (docetaxel, cisplatin, 5-FU), which was performed as preoperative chemotherapy. Therefore, we performed an electrocardiogram and contrast-enhanced CT imaging. ST elevation, tachycardia and atrial fibrillation were observed on the electrocardiogram. PTE was also observed in his left lung in CT images. We immediately started the administration of β -blocker and anticoagulant therapies. After that the patient’s subjective symptoms disappeared and the electrocardiogram showed stability two days later. Therefore, chemotherapy was continued and completed. After three weeks, a left maxillary partial resection and left radical neck dissection were performed. Following the operation, there have been no PTE symptoms and he is making good progress.
Author 佐々木, 朗
志茂, 剛
目瀬, 浩
柴田, 茜
岸本, 晃治
國定, 勇希
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  fullname: 國定, 勇希
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SubjectTerms 化学療法
口腔癌
肺血栓塞栓症
Title 口腔癌の化学療法中に発症した肺血栓塞栓症の1例
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