上唇に発生した孤立性線維性腫瘍の1例

• Published in: 日本口腔外科学会雑誌 Vol. 56; no. 11; pp. 659 - 663
• Main Authors: 清水, 英孝, 藤田, 源太郎, 今井, 智章, 道澤, 雅裕
• Format: Journal Article
• Language: Japanese
• Published: 社団法人 日本口腔外科学会 2010
• Subjects: CD34; 低頻度転移性腫瘍; 孤立性線維性腫瘍; 軟部組織腫瘍
• ISSN: 0021-5163; 2186-1579
• DOI: 10.5794/jjoms.56.659

In the WHO classification of soft tissue tumors, solitary fibrous tumor (SFT) belongs to fibroblastic/myofibroblastic tumors with intermediate malignancy (rarely metastasizing). Although this tumor occurs mainly in the pleura, extrapleuratic tumors have been reported in ubiquitous sites, including the oral cavity, with a predisposition to the buccal region. We report a rare SFT arising in the upper lip. A 70-year-old man presented with a painless mass. MR images showed a homogeneously enhanced neoplasm. The tumor was resected surgically and exhibited the histopathological features of SFT. It consisted of collagen-forming, CD34-positive fibroblastic spindle cells in a haphazard arrangement, accompanied by a prominent hemangiopericytoma-like branching vascular pattern. Although there was no evidence of local recurrence or metastasis 1 year after sugery, long-term follow-up is mandatory because of the unpredictable behavior of SFT.