循環器領域における無菌性炎症とインフラマソーム：薬物治療の現況と創薬への展望

• Published in: 日本薬理学会年会要旨集 p. 1-S03-3
• Main Author: 高橋, 将文
• Format: Journal Article
• Language: Japanese
• Published: 公益社団法人 日本薬理学会 2020
• Subjects: cell death; cytokine; immune system

Increasing evidence indicates that NLRP3 inflammasome plays a crucial role in the pathophysiology of cardiovascular diseases associated with sterile inflammation, including atherosclerosis and acute myocardial infarction (MI). NLRP3 inflammasome is a multimeric protein complex that leads to activati...