上顎歯槽部に発生した基底細胞腺腫の1例
Basal cell adenoma is a benign salivary gland tumor that most frequently occurs in the parotid gland.We report a case of basal cell adenoma of the maxillary alveolus in a man aged 62 years. Histopathological examination revealed that tumor was encapsulated with fibrous tissue and had a basal-cell-li...
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| Published in | 日本口腔外科学会雑誌 Vol. 55; no. 7; pp. 369 - 372 |
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| Main Authors | , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
社団法人 日本口腔外科学会
20.07.2009
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0021-5163 2186-1579 |
| DOI | 10.5794/jjoms.55.369 |
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| Abstract | Basal cell adenoma is a benign salivary gland tumor that most frequently occurs in the parotid gland.We report a case of basal cell adenoma of the maxillary alveolus in a man aged 62 years. Histopathological examination revealed that tumor was encapsulated with fibrous tissue and had a basal-cell-like appearance with tubulotrabecular growth. Immunohistochemically, the inner tumor cells of the tubulo-ductal structures showed positive immunoreactivity for CK7, and the outer tumor cells showed positive immunoreactivity for alpha SMA and vimentin. Most of the tumor cells were positive for p63. In addition, the MIB-1（Ki-67）labeling index was extremely low. A basal cell adenoma was thus diagnosed. |
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| AbstractList | Basal cell adenoma is a benign salivary gland tumor that most frequently occurs in the parotid gland.We report a case of basal cell adenoma of the maxillary alveolus in a man aged 62 years. Histopathological examination revealed that tumor was encapsulated with fibrous tissue and had a basal-cell-like appearance with tubulotrabecular growth. Immunohistochemically, the inner tumor cells of the tubulo-ductal structures showed positive immunoreactivity for CK7, and the outer tumor cells showed positive immunoreactivity for alpha SMA and vimentin. Most of the tumor cells were positive for p63. In addition, the MIB-1（Ki-67）labeling index was extremely low. A basal cell adenoma was thus diagnosed. |
| Author | 進藤, 正信 戸塚, 靖則 藤田, 温志 小野, 貢伸 |
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| Copyright | 2009 社団法人 日本口腔外科学会 |
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| References | 6) 楊 光宗, 本田啓二, 他：悪性を伴った口腔底基底細胞腺腫の一例. 耳鼻咽喉科臨床 76: 2911-2916 1983. 13) Dardick, I., Daley, T.D., et al.: Basal cell adenoma with myoepithelial cell-derived“stroma”.: a new major salivary gland tumor entity. Head Neck Surg 8: 257-267. 1）Seifert, G., Sobin, L.H., et al.: Histological typing of salivary gland tumours. In the series of international histological classification of tumours. 2nd ED, Spring- Verlag, Berlin, 1991, p9-38. 9) Moskow, B.S. and Baden, E.: Gingival choristoma. Report of a case. Oral Surg Oral Med Oral Pathol 18: 504-516 1964. 4) Fantasia, J.E. and Neville, B.W.: Basal cell adenomas of the minor salivary glands. A clinicopathologic study of seventeen new cases and a review of the literature. Oral Surg Oral Med Oral Pathol 50: 433-440 1980. 7) 高木勇宜, 吉田憲司, 他：頬部に発生した基底細胞腺腫の1例. 愛知学院大歯会誌 29: 135-139 1991. 10) Ellis, G.L. and Auclair, P.L.: Atlas of tumor pathology, Tumors of the major salivary glands, 3rd series, fascicle 17, Armed Forces Institute of Pathology, Washington, D.C, 1996, p80-94. 3) Tracray, A.C. and Sobin, L.H.: Histological typing of salivary gland tumours. International histological classification of tumours. No.7, World Health Organization, Geneva, 1972, p16. 12) Mori, M., Yamada, K., et al.: Multiple expression of keratins, vimentin, and S-100 protein in pleomorphic salivary adenomas. Virchows Arch B Cell Pathol Incl Mol Pathol 58: 435-444 1990. 5) 増本一真, 中埜秀史, 他：上唇に発生した基底細胞腺腫の1例. 日口外誌 51: 86-88 2005. 11) 日本唾液腺学会：唾液腺腫瘍アトラス第1版, 金原出版株式会社, 東京, 2005, p20-112. 2) Barnes, L., Eveson, J.W., et al.: The World Health Organization’s histological classification of tumours, Pathology and genetics of head and neck tumours. International Agency for Research on Cancer Press, Lyon, 2005, p261-262. 8) 当間 裕, 阿部廣幸, 他：軟口蓋に発生した基底細胞腺腫の1例. 口科誌 41: 169-174 1992. 14) Nagao, T., Sugano, I., et al.: Basal cell comparison with basal cell adenoma through assessment of cell proliferation, apotosis, and expression of p53 and bcl- 2. Cancer 82: 439-447 1998. |
| References_xml | – reference: 12) Mori, M., Yamada, K., et al.: Multiple expression of keratins, vimentin, and S-100 protein in pleomorphic salivary adenomas. Virchows Arch B Cell Pathol Incl Mol Pathol 58: 435-444 1990. – reference: 8) 当間 裕, 阿部廣幸, 他：軟口蓋に発生した基底細胞腺腫の1例. 口科誌 41: 169-174 1992. – reference: 3) Tracray, A.C. and Sobin, L.H.: Histological typing of salivary gland tumours. International histological classification of tumours. No.7, World Health Organization, Geneva, 1972, p16. – reference: 13) Dardick, I., Daley, T.D., et al.: Basal cell adenoma with myoepithelial cell-derived“stroma”.: a new major salivary gland tumor entity. Head Neck Surg 8: 257-267. – reference: 4) Fantasia, J.E. and Neville, B.W.: Basal cell adenomas of the minor salivary glands. A clinicopathologic study of seventeen new cases and a review of the literature. Oral Surg Oral Med Oral Pathol 50: 433-440 1980. – reference: 5) 増本一真, 中埜秀史, 他：上唇に発生した基底細胞腺腫の1例. 日口外誌 51: 86-88 2005. – reference: 11) 日本唾液腺学会：唾液腺腫瘍アトラス第1版, 金原出版株式会社, 東京, 2005, p20-112. – reference: 2) Barnes, L., Eveson, J.W., et al.: The World Health Organization’s histological classification of tumours, Pathology and genetics of head and neck tumours. International Agency for Research on Cancer Press, Lyon, 2005, p261-262. – reference: 7) 高木勇宜, 吉田憲司, 他：頬部に発生した基底細胞腺腫の1例. 愛知学院大歯会誌 29: 135-139 1991. – reference: 1）Seifert, G., Sobin, L.H., et al.: Histological typing of salivary gland tumours. In the series of international histological classification of tumours. 2nd ED, Spring- Verlag, Berlin, 1991, p9-38. – reference: 9) Moskow, B.S. and Baden, E.: Gingival choristoma. Report of a case. Oral Surg Oral Med Oral Pathol 18: 504-516 1964. – reference: 10) Ellis, G.L. and Auclair, P.L.: Atlas of tumor pathology, Tumors of the major salivary glands, 3rd series, fascicle 17, Armed Forces Institute of Pathology, Washington, D.C, 1996, p80-94. – reference: 6) 楊 光宗, 本田啓二, 他：悪性を伴った口腔底基底細胞腺腫の一例. 耳鼻咽喉科臨床 76: 2911-2916 1983. – reference: 14) Nagao, T., Sugano, I., et al.: Basal cell comparison with basal cell adenoma through assessment of cell proliferation, apotosis, and expression of p53 and bcl- 2. Cancer 82: 439-447 1998. |
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| Snippet | Basal cell adenoma is a benign salivary gland tumor that most frequently occurs in the parotid gland.We report a case of basal cell adenoma of the maxillary... |
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| Title | 上顎歯槽部に発生した基底細胞腺腫の1例 |
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