下顎骨中心性に発症した線維性偽腫瘍の1例

Pseudotumor with fibrous proliferation is a rare benign nonneoplastic lesion in the oral region. We report a case of intraosseous fibrous pseudotumor of the mandible. A 50-year-old woman was referred to our university hospital to undergo further evaluation of a radiolucent lesion between the lateral...

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Published in日本口腔外科学会雑誌 Vol. 58; no. 2; pp. 57 - 61
Main Authors 根岸, 明秀, 岸, 裕子, 信澤, 愛子, 山口, 徹, 横尾, 聡, 笹岡, 邦典
Format Journal Article
LanguageJapanese
Published 社団法人 日本口腔外科学会 20.02.2012
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ISSN0021-5163
2186-1579
DOI10.5794/jjoms.58.57

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Abstract Pseudotumor with fibrous proliferation is a rare benign nonneoplastic lesion in the oral region. We report a case of intraosseous fibrous pseudotumor of the mandible. A 50-year-old woman was referred to our university hospital to undergo further evaluation of a radiolucent lesion between the lateral incisor and canine of the right mandible. At presentation, no swelling was found in the alveolus of the anterior region of the mandible. A panoramic X-ray photograph revealed a radiolucent lesion causing root separation of the lateral incisor and canine. A computed tomography scan revealed mild bone swelling, a thinned cortex at the labial side of the mandible, and a low-density mass. Histopathological examination of a biopsy specimen suggested fibrous overgrowth. The lesion was intraorally extirpated under general anesthesia. Histopathological examination of the surgical specimen revealed high-density fibrous proliferation without dysplasia. There was virtually no lymphocyte infiltration. Histopathologically, the lesion was diagnosed to be a fibrous pseudotumor. No recurrence has occurred, and bone regeneration at the extirpated region is good 3 years after surgery.
AbstractList Pseudotumor with fibrous proliferation is a rare benign nonneoplastic lesion in the oral region. We report a case of intraosseous fibrous pseudotumor of the mandible. A 50-year-old woman was referred to our university hospital to undergo further evaluation of a radiolucent lesion between the lateral incisor and canine of the right mandible. At presentation, no swelling was found in the alveolus of the anterior region of the mandible. A panoramic X-ray photograph revealed a radiolucent lesion causing root separation of the lateral incisor and canine. A computed tomography scan revealed mild bone swelling, a thinned cortex at the labial side of the mandible, and a low-density mass. Histopathological examination of a biopsy specimen suggested fibrous overgrowth. The lesion was intraorally extirpated under general anesthesia. Histopathological examination of the surgical specimen revealed high-density fibrous proliferation without dysplasia. There was virtually no lymphocyte infiltration. Histopathologically, the lesion was diagnosed to be a fibrous pseudotumor. No recurrence has occurred, and bone regeneration at the extirpated region is good 3 years after surgery.
Author 笹岡, 邦典
信澤, 愛子
横尾, 聡
根岸, 明秀
山口, 徹
岸, 裕子
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References 3) Kato, T., Takano, M., et al.: A case of fibrous pseudotumor originating from tunica vaginalis testis. Acta Urol Jpn 51: 483-486 2005.
14) Earl, P.D., Lowry J.C., et al.: Intraoral inflammatory pseudotumor. Oral Surg Oral Med Oral Pathol 76: 279-283 1993.
15) Weiss, S.W. and Goldblum, J.R.: Enzinger and Weiss’s Soft Tissue Tumors. 5th Ed., Mosby Co, St Louis, 2007, p294-297.
2) 岩田裕之, 上水流雅人:陰囊内線維性偽腫瘍の1例. 泌尿紀要 47: 445-446 2001.
12) Rudy, H.N., Conn, H., et al.: Solitary xanthogranuloma of the mandible. Oral Surg Oral Med Oral Pathol 18: 262-271 1964.
17) Som, P.M. and Bergeron, R.T.: Head and neck imaging. 2nd Ed, Mosby Co, St Louis, 1991, p389-398.
4) 橋本 洋, 久岡正典, 他:炎症性偽腫瘍. 病理と臨床 25: 418-465 2007.
16) 日本歯科放射線学会編:口腔画像診断アトラス. 第1版, 医歯薬出版, 東京, 1994, 48-53頁.
5) Coffin, C.M., Watterson, J., et al.: Extrapulmonary inflammatory myofibroblastic tumor(Inflammatory pseudotumor). Am J Surg Patol 19: 859-872 1995.
13) Zegarelli, D.J., Rankow, R.M., et al: A large dental granuloma(? inflammatory pseudotumor)with unusual features: report of case. J Am Dent Assoc 89: 891-894 1974.
7) 中川 崇, 服部賢二, 他:悪性腫瘍が疑われた上顎洞炎症性偽腫瘍例. 耳鼻臨床 95: 1135-1141 2002.
8) Rodriguez-Merchan, E.C.: The haemophilic pseudotumor. Int Orthop 19: 255-260 1995.
6) Weisman, R.A. and Osguthorpe, J.D.: Pseudotumor of the head and neck masquerading as neoplasia. Laryngoscope 98: 610-614 1988.
11) Oota, S., Shibuya, H., et al.: Oral pseudotumor Benign polypoid masses following radiation therapy. Cancer 97: 1353-1357 2003.
1) Coop, M.E.: Pseudotumor of the orbit; a clinical and pathological study of 47 cases. Brit J Ophthal 45: 513-542 1961.
9) Saka, B., Stropahl, G., et al.: Traumatic myositis ossificans (ossifying pseudotumor)of temporal muscle. Int J Oral Maxillofac Surg 31: 110-111 2002.
10) Shek, A.W., Wu, P.C., et al.: Inflammatory pseudotumor of the mouth and maxilla. J Clin Pathol 49: 164-167 1996.
References_xml – reference: 11) Oota, S., Shibuya, H., et al.: Oral pseudotumor Benign polypoid masses following radiation therapy. Cancer 97: 1353-1357 2003.
– reference: 9) Saka, B., Stropahl, G., et al.: Traumatic myositis ossificans (ossifying pseudotumor)of temporal muscle. Int J Oral Maxillofac Surg 31: 110-111 2002.
– reference: 16) 日本歯科放射線学会編:口腔画像診断アトラス. 第1版, 医歯薬出版, 東京, 1994, 48-53頁.
– reference: 14) Earl, P.D., Lowry J.C., et al.: Intraoral inflammatory pseudotumor. Oral Surg Oral Med Oral Pathol 76: 279-283 1993.
– reference: 7) 中川 崇, 服部賢二, 他:悪性腫瘍が疑われた上顎洞炎症性偽腫瘍例. 耳鼻臨床 95: 1135-1141 2002.
– reference: 6) Weisman, R.A. and Osguthorpe, J.D.: Pseudotumor of the head and neck masquerading as neoplasia. Laryngoscope 98: 610-614 1988.
– reference: 1) Coop, M.E.: Pseudotumor of the orbit; a clinical and pathological study of 47 cases. Brit J Ophthal 45: 513-542 1961.
– reference: 3) Kato, T., Takano, M., et al.: A case of fibrous pseudotumor originating from tunica vaginalis testis. Acta Urol Jpn 51: 483-486 2005.
– reference: 13) Zegarelli, D.J., Rankow, R.M., et al: A large dental granuloma(? inflammatory pseudotumor)with unusual features: report of case. J Am Dent Assoc 89: 891-894 1974.
– reference: 2) 岩田裕之, 上水流雅人:陰囊内線維性偽腫瘍の1例. 泌尿紀要 47: 445-446 2001.
– reference: 10) Shek, A.W., Wu, P.C., et al.: Inflammatory pseudotumor of the mouth and maxilla. J Clin Pathol 49: 164-167 1996.
– reference: 12) Rudy, H.N., Conn, H., et al.: Solitary xanthogranuloma of the mandible. Oral Surg Oral Med Oral Pathol 18: 262-271 1964.
– reference: 15) Weiss, S.W. and Goldblum, J.R.: Enzinger and Weiss’s Soft Tissue Tumors. 5th Ed., Mosby Co, St Louis, 2007, p294-297.
– reference: 8) Rodriguez-Merchan, E.C.: The haemophilic pseudotumor. Int Orthop 19: 255-260 1995.
– reference: 5) Coffin, C.M., Watterson, J., et al.: Extrapulmonary inflammatory myofibroblastic tumor(Inflammatory pseudotumor). Am J Surg Patol 19: 859-872 1995.
– reference: 4) 橋本 洋, 久岡正典, 他:炎症性偽腫瘍. 病理と臨床 25: 418-465 2007.
– reference: 17) Som, P.M. and Bergeron, R.T.: Head and neck imaging. 2nd Ed, Mosby Co, St Louis, 1991, p389-398.
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SubjectTerms 偽腫瘍
顎骨中心性腫瘍
Title 下顎骨中心性に発症した線維性偽腫瘍の1例
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