遺伝的影響予測シミュレータ「WAMSIM」 動植物への低LET放射線照射実験における遺伝的影響を予測するWAMモデルシミュレータ
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| Published in | 保健物理 Vol. 55; no. 4; pp. 207 - 214 |
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| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | Japanese |
| Published |
日本保健物理学会
28.12.2020
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| Subjects | |
| Online Access | Get full text |
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| Author | 鈴木, 和代 真鍋, 勇一郎 土岐, 博 和田, 隆宏 佐藤, 丈 角山, 雄一 高西, 康敬 坂東, 昌子 尾上, 洋介 |
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| Author_xml | – sequence: 1 fullname: 角山, 雄一 organization: 京都大学環境安全保健機構放射性同位元素総合センター – sequence: 2 fullname: 尾上, 洋介 organization: 日本大学文理学部情報学科 – sequence: 3 fullname: 鈴木, 和代 organization: 京都大学医学部附属病院先制医療・生活習慣病研究センター – sequence: 4 fullname: 高西, 康敬 organization: 埼玉大学理工学研究科 – sequence: 5 fullname: 佐藤, 丈 organization: 埼玉大学理工学研究科 – sequence: 6 fullname: 真鍋, 勇一郎 organization: 大阪大学大学院工学研究科環境エネルギー工学専攻 – sequence: 7 fullname: 和田, 隆宏 organization: 関西大学システム理工学部物理・応用物理学科 – sequence: 8 fullname: 土岐, 博 organization: 大阪大学核物理研究センター – sequence: 9 fullname: 坂東, 昌子 organization: 大阪大学核物理研究センター |
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| Copyright | 2020 日本保健物理学会 |
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| DOI | 10.5453/jhps.55.207 |
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| EndPage | 214 |
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| References | 7) Y. TSUNOYAMA, K. SUZUKI, M. MASUGI-TOKITA, H. NAKAJIMA, Y. MANABE, T. WADA and M. BANDO; Verification of a dose rate-responsive dynamic equilibrium model on radiation-induced mutation frequencies in mice, Int. J. Radiat. Biol., 95, 1414–1420 (2019). 10) W. L. RUSSELL and E. M. KELLY; Mutation frequencies in male mice and the estimation of genetic hazards of radiation in men, Proc. Natl. Acad. Sci. USA, 79, 542–544 (1982). 4) Y. MANABE, T. WADA, Y. TSUNOYAMA, H. NAKAJIMA, I. NAKAMURA and M. BANDO; Whack-A-Mole Model: Towards unified description of biological effect caused by radiation-exposure, J. Phys. Soc. Jpn., 84, 044002 (2015). 6) M. BANDO, T. KINUGAWA, Y. MANABE, M. MASUGI, H. NAKAJIMA, K. SUZUKI, Y. TSUNOYAMA, T. WADA and H. TOKI; Study of mutation from dna to biological evolution, Int. J. Radiat. Biol., 95, 1390–1403 (2019). 1) Y. MANABE, K. ICHIKAWA and M. BANDO; Amathematical model for estimating biological damage caused by radiation, J. Phys. Soc. Jpn., 81, 104004 (2012). 5) T. WADA, Y. MANABE, I. NAKAMURA, Y. TSUNOAYMA, H. NAKAJIMA and M. BANDO; Dose and dose-rate dependence of mutation frequency under long-term exposure- a new look at DDREF from WAM model, J. Nucl. Sci. Technol., 53, 1824–1830 (2016). 9) D. L. PRESTON, E. RON, S. TOKUOKA, S. FUNAMOTO, N. NISHI, M. SODA, K. MABUCHI and K. KOMEDA; Solid cancer incidence in atomic bomb survivors: 1958–1998, Radiat. Res., 168, 1–64 (2007). 2) Y. MANABE and M. BANDO; Comparison of data on mutation frequencies of mice caused by radiation with low dose model, J. Phys. Soc. Jpn., 82, 094004 (2013). 3) I. NAKAMURA, Y. MANABE and M. BANDO; Reaction rate theory of radiation exposure and scaling hypothesis in mutation frequency, J. Phys. Soc. Jpn., 83, 114003 (2014). 8) H. J. MULLER; Artificial transmutation of the gene, Science, 66, 84–87 (1699). 11) L. B. RUSSELL; The Mouse House: a brief history of the ORNL mousegenetics program, 1947–2009, Mutat. Res., 753, 69–90 (2013). |
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| SubjectTerms | dose rate dose rate effect genetic effect hereditary effect LNT low LET LQ model mutation frequency simulator WAM model |
| Subtitle | 動植物への低LET放射線照射実験における遺伝的影響を予測するWAMモデルシミュレータ |
| Title | 遺伝的影響予測シミュレータ「WAMSIM」 |
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