EFFECT OF INLINE FILTRATION ON DELIVERY OF GENTAMICIN

We studied the effects of inline filtration on delivery of gentamicin (GM), using filter sets with a simulated system. 10mg of GM was injected into the system containing 5% dextrose in water flow rate: 50 ml/h, 10 ml/h and 2 ml/h with horizontal and vertical settings of the inline filters. With 50 m...

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Published inCHEMOTHERAPY Vol. 40; no. 1; pp. 21 - 27
Main Authors Sato, Yoshitake, Isohata, Eiichi, Iwata, Satoshi, Akita, Hironobu, Oikawa, Tadao, Sunakawa, Keisuke
Format Journal Article
LanguageJapanese
Published Japanese Society of Chemotherapy 1992
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gentamicin
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Abstract We studied the effects of inline filtration on delivery of gentamicin (GM), using filter sets with a simulated system. 10mg of GM was injected into the system containing 5% dextrose in water flow rate: 50 ml/h, 10 ml/h and 2 ml/h with horizontal and vertical settings of the inline filters. With 50 ml/h, delivery of GM of Pall showed nearly the same delivery pattern as compared with no filter setting. However, JMS and IVEX 2 showed slight differences. With 10 ml/h and 2 ml/h those differences became more significant. Delivery of GM was influenced by the priming volume of the fi lters, and increasingly so at slow flow rates. Filter settings also influenced the delivery of GM. Not only priming volumes of the filters affect delivery of drugs, fiilter designs also have an influence. Although the use of inline filters is important in the pediatric field, their characteristics need careful consideration.
AbstractList We studied the effects of inline filtration on delivery of gentamicin (GM), using filter sets with a simulated system. 10mg of GM was injected into the system containing 5% dextrose in water flow rate: 50 ml/h, 10 ml/h and 2 ml/h with horizontal and vertical settings of the inline filters. With 50 ml/h, delivery of GM of Pall showed nearly the same delivery pattern as compared with no filter setting. However, JMS and IVEX 2 showed slight differences. With 10 ml/h and 2 ml/h those differences became more significant. Delivery of GM was influenced by the priming volume of the fi lters, and increasingly so at slow flow rates. Filter settings also influenced the delivery of GM. Not only priming volumes of the filters affect delivery of drugs, fiilter designs also have an influence. Although the use of inline filters is important in the pediatric field, their characteristics need careful consideration.
Author Iwata, Satoshi
Isohata, Eiichi
Akita, Hironobu
Oikawa, Tadao
Sunakawa, Keisuke
Sato, Yoshitake
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  fullname: Sato, Yoshitake
  organization: Department of Pediatrics, Ohta General Hospital
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  fullname: Isohata, Eiichi
  organization: Deparoment of Pediatrics, Keio University School of Medicine
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  fullname: Iwata, Satoshi
  organization: Deparoment of Pediatrics, Keio University School of Medicine
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  fullname: Akita, Hironobu
  organization: Deparoment of Pediatrics, Keio University School of Medicine
– sequence: 5
  fullname: Oikawa, Tadao
  organization: Deparoment of Pediatrics, Keio University School of Medicine
– sequence: 6
  fullname: Sunakawa, Keisuke
  organization: Department of Pediatrics, Second Tokyo National Hospital
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References 5) Rusmin S, Welton S. Deluca P, et. al.: Effect of inline filtration on the potency of drugs administered intravenously. Am. J. Hosp. Pharm. 34: 1071-1074, 1977
10) Weber S S, Wood W A, Jackson E A: Availability of insulin from parenteral nutrient solutions. Am. J. Hosp. Pharm. 34: 353-357, 1977
14) 砂川慶介, 秋田博伸, 城崎慶治, 岩田敏, 岩崎由紀夫, 佐藤吉壮, 東條雅宏, 若林良, 早野紳哉, 小佐野満, 松尾武夫, 山田善三郎, 鈴木博子, 市橋保雄: 小児におけるgentamicin点滴静注法の薬動力学的研究. Jap. J. Antibiotics 36: 47-54, 1983
16) 中沢進, 佐藤肇, 平間裕一, 新納憲司, 成田章, 中沢進一, 近岡秀次郎, 田添克衛: 小児に対するgentamicin点滴静注法に関する検討. 薬理と治療10: 5527-5533, 1982
8) Stiles M L, Allen L V: Retention of drugs during in-line filtration of parenteral solitions. Infusion 67-69, May/June, 1979
15) 砂川慶介, 秋田博伸, 南里清一郎, 山下直哉, 堀田昌宏, 城崎慶治, 岩田敏, 岩崎由紀夫, 金光岳文, 小佐野満, 市橋保雄, 広瀬誠, 郡建男, 高橋弘剛: 小児におけるtobramycin静脈内投与法の検討. 感染症学誌55: 524-533, 1981
3) Wingert T D, Levin S R: Insulin adsorption to an air-eliminating inline filter. Am. J. Hosp. Pharm. 38: 382-383, 1981
9) Stennett D J, Simonson W, Ayres J W: Effect of membrane filtration on 10 mg/ml cefazolin admixtures. Am. J. Hosp. Pharm. 36: 657-660, 1979
12) 西園寺克, 林鷹之, 小酒井鷲, 工藤快訓, 太田抜徳, 河合忠, 安達房世, 国井乙彦, 片岡陳正. 守殿貞夫, 石神寝次, 井直隆, 只野寿太郎, 熊沢浄一: アミノ配糊体系薬物における蛍光偏光免疫測定法のTherapeutic Drug Monltoringへの応用. 生物献料分析6: 24-39, 1983
17) 佐藤吉壮, 磯畑栄一, 渡辺洋子, 緒方勤, 鈴木敏雄, 石川和夫, 秋田博伸, 岩田敏, 草野正一, 砂川慶介, 横田隆夫, 老川忠雄, 市橋保雄: 新生児におけるgentamicin点滴静注投与法の検討. Chemotherapy 36: 412-420, 1988
2) Baumgartner T G, Curry S H, Shaw M A, et.al.: Nitroglycerin adsorption to a new 0.2-micron posidyne filter material. Am. J. IV Ther. & Clin. Nut. 7-14, Feb. 1984
7) Rusmin S Deluca P. P: Effect of in-line intravenous filtration on the potency of potassium penicillin G. Bull. Parenteral Drug Assoc. 30: 64-72, 1976
6) Butler L D, Munson J M, Deluca P P: Effect of inline filtration on the potency of low-dose drugs. Am. J. Hosp. Pharm.37: 935-941, 1980
1) Thompson D F, Thompson G D, Hedick P J: The effect of inline filtration on pediatric doses of gentamicin and tobramycin. Infusion 8: 31-32, 1984
13) 紺野畠俊: 小児におけるaminoglycoside剤の使用法. 臨床と細菌6: 346, 1979
4) Kanke M, Eubanks J L, Deluca P P: Binding of selected drugs to a “treated” inline filter. Am. J. Hosp. Pharm. 40: 1323-1328, 1983
11) 全自動蛍光偏光分析装置使用の手引き. ダイナポツト株式会社
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Title EFFECT OF INLINE FILTRATION ON DELIVERY OF GENTAMICIN
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