CuBr2-promoted cyclization and bromination of arene-alkynes: C-Br bond formation via reductive elimination of Cu(III) species

• Published in: ORGANIC CHEMISTRY FRONTIERS Vol. 3; no. 7; pp. 852 - 855
• Main Authors: Liu, Wangsheng, Chen, Jinjin, Jin, Ruiwen, Xu, Dawen, Li, Yawei, Ba, Feifei, Gu, Guangxin, Kuang, Yunyan, Guo, Hao
• Format: Journal Article
• Language: English; Japanese
• Published: CAMBRIDGE Royal Soc Chemistry 01.01.2016
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; HETEROARYL BROMIDES; CARBOIODINATION; RESONANCE; HALOGEN EXCHANGE; ARYL HALIDES; COMPLEXES; 1,3-HALOGEN MIGRATION; FINKELSTEIN REACTION; FLUORINATION; DERIVATIVES

A CuBr2-promoted cyclization and bromination of arene-alkyne substrates has been developed, affording 9-bromophenanthrene derivatives highly efficiently. This reaction provides a novel and efficient protocol for C-Br bond formation from an inorganic bromine source via the reductive elimination of th...