F-05 前頭葉損傷に伴う虚再認傾向の増加

• Published in: The Japanese Journal of Psychonomic Science Vol. 19; no. 1; pp. 45 - 46
• Main Authors: 梅田, 聡, 小谷津, 孝明
• Format: Journal Article
• Language: Japanese
• Published: 日本基礎心理学会 2000; The Japanese Psychonomic Society
• Subjects: false recognition; frontal lobe lesion; higher-order cognitive dysfunction; orbitofrontal cortex; ventromedial prefrontal cortex
• ISSN: 0287-7651; 2188-7977
• DOI: 10.14947/psychono.KJ00004413825

In the present study, we used the typical false recognition paradigm to test a hypothesis that the ventromedial prefrontal cortex (VMPFC) mediates context judgment and retrieving past events. Eight VMPFC patients and ten normal control subjects were first requested to learn 18 sets of 14 semantic associates. In the test phase, the participants were asked to recognize for pairedwords including true words, related lures, and unrelated lures. The VMPFC patients showed significantly higher false alarm rate than the normal subjects for lure words. A further analysis suggests that the VMPFC patients were more likely to fail to judge contexts and to retrieve past events.