HEMODYNAMIC AND METABOLIC STUDIES OF LEFT VENTRICULAR BYPASS WITH A CENTRIFUGAL BLOOD PUMP

We evaluated the effectiveness of a centrifugal left ventricular assist device in dogs with acute myocardial infarction and in unanesthetized goats with normal heart. Pulse pressure decreased half of normal at 50% and was gone nonpulsatile flow at 100% left ventricular bypass. RV output and renal bl...

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Published inJinko Zoki Vol. 14; no. 3; pp. 1108 - 1111
Main Authors YADA, I., SAITO, K., KUSAGAWA, M., HATTORI, R., MIYAMURA, K., WEI, C. M.
Format Journal Article
LanguageJapanese
Published JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1985
一般社団法人 日本人工臓器学会
Subjects
Artificial heart
Bypass flow
Centrifugal pump
left ventricular bypass
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ISSN0300-0818
1883-6097
DOI10.11392/jsao1972.14.1108

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Summary:We evaluated the effectiveness of a centrifugal left ventricular assist device in dogs with acute myocardial infarction and in unanesthetized goats with normal heart. Pulse pressure decreased half of normal at 50% and was gone nonpulsatile flow at 100% left ventricular bypass. RV output and renal blood flow increased following increasing left ventricular bypass flow. But carotid blood flow was no significant change. TTI reduction decreased in 25.6+11.2% at 50% and 52.3+21.3% at 100% LV bypass respectively. Serum cathecholamine levels and renal functions remained normal. These data indicate no untoward effects as a result of prolonged nonpulsatile perfusion.
ISSN:0300-0818
1883-6097
DOI:10.11392/jsao1972.14.1108