VENO-ARTERIAL BYPASS OF CENTRIFUGAL PUMP WITHOUT AN OXYGENATOR ON THE DESCENDING THORACIC AORTA CLAMPING

Ten dogs were examined for surgery of the descending thoracic aorta clamping with simplified veno-arterial bypass (V-A bypass) using a centrifugal pump (Bio-pump) without oxygenator. Bypass route was made between SVC or the right atrium and the femoral artery. Aorta clamping time was set at 2 hours....

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Published inJinko Zoki Vol. 19; no. 1; pp. 485 - 488
Main Authors UWATOKO, T., KATO, R., TSUCHIOKA, H., ASAI, T., OHTA, T., KAZUI, H., HOSAKA, M., BOKU, K., IKEUCHI, K., KONDP, M.
Format Journal Article
LanguageJapanese
Published JAPANESE SOCIETY FOR ARTIFICIAL ORGANS 1990
一般社団法人 日本人工臓器学会
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ISSN0300-0818
1883-6097
DOI10.11392/jsao1972.19.485

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Abstract Ten dogs were examined for surgery of the descending thoracic aorta clamping with simplified veno-arterial bypass (V-A bypass) using a centrifugal pump (Bio-pump) without oxygenator. Bypass route was made between SVC or the right atrium and the femoral artery. Aorta clamping time was set at 2 hours. Blood gas, blood pressures at proximal and distal sides of aortic clamp and urinary output were examined. All dogs survived 1to2 weeks and were referred laboratory data to the sacrificial death. Controlled study was done by left heart bypass (A-A bypass) between the left atrium and the femoral artery in 4 dogs. In the V -A bypass group, PaO2 and O2 saturation of perfusion blood were 59±24mmHg (21-129mmHg) and 83±14% (33-99%), respectively. Laboratory data were not significantly different from those of the left heart bypass group. The results show that V-A bypass with centrifugal pump is suitable for assist circulatim during descending thoracic aorta clamping.
AbstractList Ten dogs were examined for surgery of the descending thoracic aorta clamping with simplified veno-arterial bypass (V-A bypass) using a centrifugal pump (Bio-pump) without oxygenator. Bypass route was made between SVC or the right atrium and the femoral artery. Aorta clamping time was set at 2 hours. Blood gas, blood pressures at proximal and distal sides of aortic clamp and urinary output were examined. All dogs survived 1to2 weeks and were referred laboratory data to the sacrificial death. Controlled study was done by left heart bypass (A-A bypass) between the left atrium and the femoral artery in 4 dogs. In the V -A bypass group, PaO2 and O2 saturation of perfusion blood were 59±24mmHg (21-129mmHg) and 83±14% (33-99%), respectively. Laboratory data were not significantly different from those of the left heart bypass group. The results show that V-A bypass with centrifugal pump is suitable for assist circulatim during descending thoracic aorta clamping. 下行大動脈遮断中の補助循環として、血液酸素化装置は用いず、遠心式血液ポンプを使用し、静脈血を還流させるveno-arterial bypass法を行い、術後の臓器障害等について実験的に検討を行った。雑種成犬を用い、veno-arterial bypassを10例(V-A群)、この対照に左心バイパスを4例(A-A群)に行った。大動脈遮断は2時間行い、中枢側と末梢側の動脈圧、血液ガス、術前後のトランスアミナーゼ、尿素窒素、クレアチニン、CPK、LDHを経時的に測定した。術後1~2週間後に犠牲死せしめ、肝、腎の組織について塞栓の有無を検索した。V-A群の送血血液のPaO2、酸素飽和度はA-A群に比べ著明に低値を示したが、術後に対麻痺等の合併症を発生したものはなく、術後の血清生化学検査では両群間に有意差は認めず、また組織学的に明らかな塞栓を有するものもなかった。
Ten dogs were examined for surgery of the descending thoracic aorta clamping with simplified veno-arterial bypass (V-A bypass) using a centrifugal pump (Bio-pump) without oxygenator. Bypass route was made between SVC or the right atrium and the femoral artery. Aorta clamping time was set at 2 hours. Blood gas, blood pressures at proximal and distal sides of aortic clamp and urinary output were examined. All dogs survived 1to2 weeks and were referred laboratory data to the sacrificial death. Controlled study was done by left heart bypass (A-A bypass) between the left atrium and the femoral artery in 4 dogs. In the V -A bypass group, PaO2 and O2 saturation of perfusion blood were 59±24mmHg (21-129mmHg) and 83±14% (33-99%), respectively. Laboratory data were not significantly different from those of the left heart bypass group. The results show that V-A bypass with centrifugal pump is suitable for assist circulatim during descending thoracic aorta clamping.
Author HOSAKA, M.
IKEUCHI, K.
UWATOKO, T.
TSUCHIOKA, H.
KATO, R.
OHTA, T.
BOKU, K.
KAZUI, H.
ASAI, T.
KONDP, M.
Author_FL 保坂 実
太田 敬
上床 邦彦
近藤 三隆
浅井 忠彦
加藤 量平
朴 一彦
土岡 弘通
池内 克彦
数井 秀器
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DocumentTitleAlternate 遠心式血液ポンプ(Bio‐pump)を用いたV‐Aバイパスの実験的研究
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References 6) Kirsh M. M. et. al.: Repair of acute traumatic rupture of the aorta without extracorporeal circulation.: Ann. Thorac. Surg. 10: 227, 1970.
3) 岡田昌義ほか: 補助循環法の理論: 補助循環法 1: 5, 1988.
9) 合田俊宏ほか: 補助心臓―モデル閉鎖循環における遠心ポンプとローラーポンプの比較検討.: 心臓 15: 1283, 1983.
1) Crawford E. S. et. al.: Graft replacement of aneurysm in descending thoracic aorta: Result without bypass or shunting.: Surgery 89: 73, 1981.
2) Hamerlijnck R. P. et. al.: Surgical correction of descending thoracic aortic aneurysms under simple aortic crossclamping.: J. Vasc. Surg. 9: 568, 1989.
8) Young J. N. et. al.: The management of descending thoracic aortic aneurysms using heparinless femoral venoarterial bypass.: chest 79: 438. 1981.
5) Garlson D. E. et. al.: Surgical treatment of aneurysms of the descending thoracic aorta: an analysis of 85 patients.: Ann. Thorac. Surg. 35: 58, 1983.
7) May I. A. et. al.: Heparinless femoral venoarterial bypass without an oxygenator for surgery on the descending thoracic aorta.: J. Thorac. Cardiovasc. Surg. 73: 387, 1977.
10) 松倉裕美ほか: 体外循環中の血小板保護に関する実験的研究.: 胸部外科 36: 890, 1983.
4) Livesay J. J. et. al.: Surgical experience in descending thoracic aneurysmectomy with and without adjuncts to avoidischemia.: Ann. Thorac. Surg. 3937, 1985.
References_xml – reference: 1) Crawford E. S. et. al.: Graft replacement of aneurysm in descending thoracic aorta: Result without bypass or shunting.: Surgery 89: 73, 1981.
– reference: 4) Livesay J. J. et. al.: Surgical experience in descending thoracic aneurysmectomy with and without adjuncts to avoidischemia.: Ann. Thorac. Surg. 3937, 1985.
– reference: 8) Young J. N. et. al.: The management of descending thoracic aortic aneurysms using heparinless femoral venoarterial bypass.: chest 79: 438. 1981.
– reference: 9) 合田俊宏ほか: 補助心臓―モデル閉鎖循環における遠心ポンプとローラーポンプの比較検討.: 心臓 15: 1283, 1983.
– reference: 2) Hamerlijnck R. P. et. al.: Surgical correction of descending thoracic aortic aneurysms under simple aortic crossclamping.: J. Vasc. Surg. 9: 568, 1989.
– reference: 5) Garlson D. E. et. al.: Surgical treatment of aneurysms of the descending thoracic aorta: an analysis of 85 patients.: Ann. Thorac. Surg. 35: 58, 1983.
– reference: 7) May I. A. et. al.: Heparinless femoral venoarterial bypass without an oxygenator for surgery on the descending thoracic aorta.: J. Thorac. Cardiovasc. Surg. 73: 387, 1977.
– reference: 6) Kirsh M. M. et. al.: Repair of acute traumatic rupture of the aorta without extracorporeal circulation.: Ann. Thorac. Surg. 10: 227, 1970.
– reference: 3) 岡田昌義ほか: 補助循環法の理論: 補助循環法 1: 5, 1988.
– reference: 10) 松倉裕美ほか: 体外循環中の血小板保護に関する実験的研究.: 胸部外科 36: 890, 1983.
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SubjectTerms Aortic clamping
Centriugal pump
V-A bypass
Title VENO-ARTERIAL BYPASS OF CENTRIFUGAL PUMP WITHOUT AN OXYGENATOR ON THE DESCENDING THORACIC AORTA CLAMPING
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