顕性糖尿病性腎症における病理組織学的所見と蛋白尿との関連

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Published in日本腎臓学会誌 Vol. 41; no. 5; pp. 475 - 485
Main Authors 岡田, 知也, 長岡, 由女, 篠, 朱美, 清水, 亨, 韓, 明基, 中尾, 俊之, 日高, 宏実, 山田, 親行, 大谷, 方子, 吉野, 麻紀, 松本, 博
Format Journal Article
LanguageJapanese
Published 社団法人 日本腎臓学会 1999
Online AccessGet full text
ISSN0385-2385
1884-0728
DOI10.14842/jpnjnephrol1959.41.475

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Author 篠, 朱美
吉野, 麻紀
山田, 親行
松本, 博
中尾, 俊之
日高, 宏実
大谷, 方子
清水, 亨
岡田, 知也
長岡, 由女
韓, 明基
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References 10. Yokoyama H, Tomonaga O, Hirayama M, Ishii A, Takeda M, Babazono T, Ujihara U, Takahashi C, Onioni Y. Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients. Diabetologia 1997; 40: 405-11.
19. Morita T, Yamamoto T, Churg J. Mesangiolysis:an update.Am J Kidney Dis 1998; 31: 559-73.
1. American Diabetes Association. Diabetic nephropathy. Diabetes Care 1998; 21 (Suppl 1) :s50-3.
9. Stout LC, Kumar S, Whorton EB. Focal mesangiolysis and the pathogenesis of the Kimmelstiel-Wilson nodule. Hum Pathol 1993; 24: 77-89.
17. Shoji T, Kanda T, Nakamura H, Hayashi T, Okada N, Nakanishi I, Shimizu Y, Tsubakihara Y. Are glomerular lesions alternatives to microalbuminuria in predicting later progression of diabetic nephropathy? Clin Nephrol 1996; 45: 367-71.
11. Ruggenenti P, Gambara V, Perna A, Bertani T, Remuzzi G. The nephropathy of non-insulin-dependent diabetes:predictors of outcome relative to diverse patterns of renal injury. J Am Soc Nephrol 1998; 9: 2336-43.
6. Suzuki Y, Ueno M, Hayashi H, Nishi S, Satou H, Karasawa R, Inn H, Suzuki S, Maruyama Y, Arakawa M. A light microscopic study of glomerulosclerosis in Japanese patients with noninsulin-dependent diabetes mellitus:the relationship between clinical and histological features. Clin Nephrol 1994; 42: 155-62.
8. Gellman DD, Pirani CL, Soothill JF, Muehrcke RC, Kark RM. Diabetic nephropathy:A clinical and pathologic study based on renal biopsies. Medicine 1959;38:321-67.
15.岡田知也,長岡由女,山田親行,篠 朱美,花田麻紀,日高宏実,韓 明基,松本 博,中尾俊之.顕性糖尿病性腎症における糸球体病変と腎機能低下との関連.日腎会誌1998;40:193.
31. Christensen PK, Hansen HP, Parving HH. Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients. Kidney Int 1997; 52: 1369-74.
26. Ziyadeh FN. Significance of tubulointerstitial changes in diabetic renal disease. Kidney Int 1996; 49 (Suppl 54) : s10-3.
13. Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. New Engl J Med 1998; 339: 1448-56.
5. Kanauchi M, Ishihara K, Nishioka H, Nishiura K, Dohi K. Glomerular lesions in patients with non-insulin-dependent diabetes mellitus and microalbuminuria. Intern Med 1993;32:753-7.
16. Thomsen OF, Andersen AR, Christiansen JS, Deckert T. Renal changes in long-term Type 1 (insulin-dependent) diabetic patients with and without clinical nephropathy:a light microscopic, morphometric study of autopsy material. Diabetologia 1984; 26: 361-5.
3. Harris RD, Steffes MW, Bilous RW, Sutherland DER, Mauer SM. Global glomerular sclerosis and glomerular arteriolar hyalinosis in insulin dependent diabetes. Kidney Int 1991; 40: 107-14.
12. Remuzzi G, Ruggenenti P, Benigni A. Understanding the nature of renal disease progression. Kidney Int 1997; 51: 2-15.
18. 岡田知也,中尾俊之,金澤真雄,能登谷洋子.顕性糖尿病性腎症における糸球体病変の進行度と腎機能との関連に関する検討.糖尿病1998;41(Suppll);270.
24. Nath KA. The role of tubulo-interstitial processes in progressive renal disease. In:El Nahas AM, Mallick NP, Anderson S (eds) Prevention of Progressive Chronic Renal Failure. Oxford:Oxford Medical Publications, 1993: 62-97.
29. Taft JL, Nolan CJ, Yeung SP, Hewitson TD, Martin FIR. Clinical and histological correlations of decline in renal function in diabetic patients with proteinuria. Diabetes 1994; 43: 1046-51.
21. 高澤和也,加藤珠代,吉村光弘,木田 寛.糖尿病性腎症における結節性病変の再検討と臨床的意義.日腎会誌1998:40:192.
22. Morita T, Yamada Y. The cortical distribution pattern of diabetic glomerulopathy. Diabetologia 1986; 29: 673.
27. Shena FP, Gesualdo L, Grandaliano G, Montinaro V. Progression of renal damage in human glomerulonephritides:is there sleight of hand in winning the game?Kidney Int 1997;52:1439-57.
7. Ueno M, Kawashima S, Nishi S, Shimada H, Karasawa R, Suzuki Y, Maruyama Y, Arakawa M. Tubulointerstitial lesions in non-insulin dependent diabetes mellitus. Kidney Int 1997;52 (Suppl 63): sl91-4.
23. Pedagogos E, Hewitson T, Fraser I, Nicholls K, Becker G. Myofibrobrasts and arteriolar sclerosis in human diabetic nephropathy. Am J Kidney Dis 1997; 29: 912-8.
25. Bohle A, Wehrmann M, Bogenschutz O, Batz C, Muller CA. The pathogenesis of chronic renal failure in diabetic nephropathy: investigation of 488 cases of diabetic glomer-ulosclerosis. Pathol Res Pract 1991; 187: 251-9.
14. Satto Y, Kida H, Takeda S, Yoshimura M, Yokoyama H, Koshino Y, Hattori N. Mesangiolysis in diabetic glomeruli:its role in the formation of nodular lesions. Kidney Int 1988:34:389-96.
20. 木田 寛,高澤和也,加藤珠代,吉村光弘.糖尿病性腎症にみられる高度蛋白尿の病理学的背景とその成因について.日腎会誌1998;40:192.
28. Fioretto P, Steffes MW, Sutherland DER, Mauer M. Sequential renal biopsies in insulin-dependent diabetic patients structural factors associated with clinical progression. Kidney Int 1995; 48: 1929-35.
30. Weir MR, Dworkin LD. Antihypertensive drugs, dietary salt, and renal protection:how low should you go and with which therapy? Am J Kidney Dis 1998; 32: 1-22.
2. Mauer SM, Steffes MW, Ellis EN, Sutherland DER, Brown DM, Goetz FC. Structural-functional relationships in diabetic nephropathy. J Clin Invest 1984;74:1143-55.
4. Lane PH, Steffes MW, Fioretto P, Mauer SM. Renal interstitial expansion in insulin-dependent diabetes mellitus. Kidney Int 1993; 43: 661-7.
References_xml – reference: 6. Suzuki Y, Ueno M, Hayashi H, Nishi S, Satou H, Karasawa R, Inn H, Suzuki S, Maruyama Y, Arakawa M. A light microscopic study of glomerulosclerosis in Japanese patients with noninsulin-dependent diabetes mellitus:the relationship between clinical and histological features. Clin Nephrol 1994; 42: 155-62.
– reference: 2. Mauer SM, Steffes MW, Ellis EN, Sutherland DER, Brown DM, Goetz FC. Structural-functional relationships in diabetic nephropathy. J Clin Invest 1984;74:1143-55.
– reference: 15.岡田知也,長岡由女,山田親行,篠 朱美,花田麻紀,日高宏実,韓 明基,松本 博,中尾俊之.顕性糖尿病性腎症における糸球体病変と腎機能低下との関連.日腎会誌1998;40:193.
– reference: 9. Stout LC, Kumar S, Whorton EB. Focal mesangiolysis and the pathogenesis of the Kimmelstiel-Wilson nodule. Hum Pathol 1993; 24: 77-89.
– reference: 25. Bohle A, Wehrmann M, Bogenschutz O, Batz C, Muller CA. The pathogenesis of chronic renal failure in diabetic nephropathy: investigation of 488 cases of diabetic glomer-ulosclerosis. Pathol Res Pract 1991; 187: 251-9.
– reference: 26. Ziyadeh FN. Significance of tubulointerstitial changes in diabetic renal disease. Kidney Int 1996; 49 (Suppl 54) : s10-3.
– reference: 4. Lane PH, Steffes MW, Fioretto P, Mauer SM. Renal interstitial expansion in insulin-dependent diabetes mellitus. Kidney Int 1993; 43: 661-7.
– reference: 11. Ruggenenti P, Gambara V, Perna A, Bertani T, Remuzzi G. The nephropathy of non-insulin-dependent diabetes:predictors of outcome relative to diverse patterns of renal injury. J Am Soc Nephrol 1998; 9: 2336-43.
– reference: 19. Morita T, Yamamoto T, Churg J. Mesangiolysis:an update.Am J Kidney Dis 1998; 31: 559-73.
– reference: 20. 木田 寛,高澤和也,加藤珠代,吉村光弘.糖尿病性腎症にみられる高度蛋白尿の病理学的背景とその成因について.日腎会誌1998;40:192.
– reference: 10. Yokoyama H, Tomonaga O, Hirayama M, Ishii A, Takeda M, Babazono T, Ujihara U, Takahashi C, Onioni Y. Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients. Diabetologia 1997; 40: 405-11.
– reference: 27. Shena FP, Gesualdo L, Grandaliano G, Montinaro V. Progression of renal damage in human glomerulonephritides:is there sleight of hand in winning the game?Kidney Int 1997;52:1439-57.
– reference: 22. Morita T, Yamada Y. The cortical distribution pattern of diabetic glomerulopathy. Diabetologia 1986; 29: 673.
– reference: 5. Kanauchi M, Ishihara K, Nishioka H, Nishiura K, Dohi K. Glomerular lesions in patients with non-insulin-dependent diabetes mellitus and microalbuminuria. Intern Med 1993;32:753-7.
– reference: 18. 岡田知也,中尾俊之,金澤真雄,能登谷洋子.顕性糖尿病性腎症における糸球体病変の進行度と腎機能との関連に関する検討.糖尿病1998;41(Suppll);270.
– reference: 24. Nath KA. The role of tubulo-interstitial processes in progressive renal disease. In:El Nahas AM, Mallick NP, Anderson S (eds) Prevention of Progressive Chronic Renal Failure. Oxford:Oxford Medical Publications, 1993: 62-97.
– reference: 21. 高澤和也,加藤珠代,吉村光弘,木田 寛.糖尿病性腎症における結節性病変の再検討と臨床的意義.日腎会誌1998:40:192.
– reference: 30. Weir MR, Dworkin LD. Antihypertensive drugs, dietary salt, and renal protection:how low should you go and with which therapy? Am J Kidney Dis 1998; 32: 1-22.
– reference: 12. Remuzzi G, Ruggenenti P, Benigni A. Understanding the nature of renal disease progression. Kidney Int 1997; 51: 2-15.
– reference: 8. Gellman DD, Pirani CL, Soothill JF, Muehrcke RC, Kark RM. Diabetic nephropathy:A clinical and pathologic study based on renal biopsies. Medicine 1959;38:321-67.
– reference: 29. Taft JL, Nolan CJ, Yeung SP, Hewitson TD, Martin FIR. Clinical and histological correlations of decline in renal function in diabetic patients with proteinuria. Diabetes 1994; 43: 1046-51.
– reference: 7. Ueno M, Kawashima S, Nishi S, Shimada H, Karasawa R, Suzuki Y, Maruyama Y, Arakawa M. Tubulointerstitial lesions in non-insulin dependent diabetes mellitus. Kidney Int 1997;52 (Suppl 63): sl91-4.
– reference: 14. Satto Y, Kida H, Takeda S, Yoshimura M, Yokoyama H, Koshino Y, Hattori N. Mesangiolysis in diabetic glomeruli:its role in the formation of nodular lesions. Kidney Int 1988:34:389-96.
– reference: 17. Shoji T, Kanda T, Nakamura H, Hayashi T, Okada N, Nakanishi I, Shimizu Y, Tsubakihara Y. Are glomerular lesions alternatives to microalbuminuria in predicting later progression of diabetic nephropathy? Clin Nephrol 1996; 45: 367-71.
– reference: 3. Harris RD, Steffes MW, Bilous RW, Sutherland DER, Mauer SM. Global glomerular sclerosis and glomerular arteriolar hyalinosis in insulin dependent diabetes. Kidney Int 1991; 40: 107-14.
– reference: 13. Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. New Engl J Med 1998; 339: 1448-56.
– reference: 16. Thomsen OF, Andersen AR, Christiansen JS, Deckert T. Renal changes in long-term Type 1 (insulin-dependent) diabetic patients with and without clinical nephropathy:a light microscopic, morphometric study of autopsy material. Diabetologia 1984; 26: 361-5.
– reference: 31. Christensen PK, Hansen HP, Parving HH. Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients. Kidney Int 1997; 52: 1369-74.
– reference: 1. American Diabetes Association. Diabetic nephropathy. Diabetes Care 1998; 21 (Suppl 1) :s50-3.
– reference: 23. Pedagogos E, Hewitson T, Fraser I, Nicholls K, Becker G. Myofibrobrasts and arteriolar sclerosis in human diabetic nephropathy. Am J Kidney Dis 1997; 29: 912-8.
– reference: 28. Fioretto P, Steffes MW, Sutherland DER, Mauer M. Sequential renal biopsies in insulin-dependent diabetic patients structural factors associated with clinical progression. Kidney Int 1995; 48: 1929-35.
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