生体模倣傾斜機能アパタイトの開発 rhBMP-2による骨誘導
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| Published in | 日本口腔インプラント学会誌 Vol. 18; no. 4; pp. 540 - 548 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | Japanese |
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公益社団法人 日本口腔インプラント学会
31.12.2005
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0914-6695 2187-9117 |
| DOI | 10.11237/jsoi.18.540 |
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| Author | 有末, 眞 村田, 勝 赤澤, 敏之 入江, 一元 佐々木, 智也 |
|---|---|
| Author_FL | AKAZAWA Toshiyuki IRIE Kazuharu SASAKI Tomoya ARISUE Makoto MURATA Masaru |
| Author_FL_xml | – sequence: 1 fullname: SASAKI Tomoya – sequence: 2 fullname: MURATA Masaru – sequence: 3 fullname: AKAZAWA Toshiyuki – sequence: 4 fullname: IRIE Kazuharu – sequence: 5 fullname: ARISUE Makoto |
| Author_xml | – sequence: 1 fullname: 有末, 眞 organization: 北海道医療大学歯学部口腔外科学第二講座 – sequence: 1 fullname: 村田, 勝 organization: 北海道医療大学歯学部口腔外科学第二講座 – sequence: 1 fullname: 赤澤, 敏之 organization: 北海道立工業試験場 – sequence: 1 fullname: 入江, 一元 organization: 北海道医療大学歯学部口腔解剖学第一講座 – sequence: 1 fullname: 佐々木, 智也 organization: 北海道医療大学歯学部口腔外科学第二講座 |
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| Copyright | 2005 公益社団法人日本口腔インプラント学会 |
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| DocumentTitleAlternate | Development of Biomimetic Functionally Graded Hydroxyapatite : Bone Induction with Recombinant Human BMP-2 |
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| References | 6) 島田勝弘，陳 明裕，武 宣昭，内藤 勲，高橋信彰，岩田耕三，梅田正博，栗岡一人，川本博男，寺延 治，島田桂吉，川井隆夫：HAPとβ-TCPの骨伝導性および安定性に関する組織学的研究―家兎脛骨骨髄腔内移植実験の長期観察結果について―；日口腔インプラント誌，2：54-61，1989 7) 小笠原健文，五百蔵一男，藤原寿彦，阿多史雄，白川禎則：アパタイトブロック長期填入例のCTによる検討 (抄)．日口腔インプラント誌，13：180，2000 3) 落合栄樹：自家新鮮海綿骨および同種脱脂凍結乾燥海綿骨の筋膜下移植における新鮮遊離骨膜・脱脂凍結乾燥骨膜の被包効果に関する実験的研究；日口外誌，38：1041-1054，1992 10) MIYAMOTO, S., TAKAOKA, K., OKADA, T., YOSHIKAWA, H., HASHIMOTO, J., SUZUKI, S. and ONO, K.:Polylactic acid-polyethylene glycol block copolymer;Clin. Orthop. Relat. Res., 294:333-343, 1993. 24) BASSETT, C.A.L.:Current concepts of bone formation;J. Bone Joint Surg., 44-A:1217-1244, 1962. 25) TSURUGA, E., TAKITA, H., ITOH, H., WAKISAKA, Y. and KUBOKI, Y.:Pore size of porous hydroxyapatite as the cell-substratum controls BMP-nduced osteogenesis;J.Biochem., 121:317-324, 1997. 13) WANG, E.A., ROSEN, V.D., ALESSANDRO, J.S.,BAUDUY, M., CORDES, P., HARADA, T., ISRAEL, D.A., HEWICK, R.M., KERNS, K.M., LAPAN, P., LUXENBERG, D.P., MCQUAID, D., MOUTSATSOS, LK., NOVE, J. and WOZNEY, J.M.:Recombinant human bone morphogenetic protein induces bone formation;Proc. Natl. Acad. Sci. USA, 87:2220-2224, 1990. 17) URIST, M.R. and NILSSON, O.:Bone regeneration under the influence of a bone morphogenetic protein (BMP) beta tricalcium phosphate (TCP) composite inskull trephine defects in dogs;Clin. Orthop. Relat. Res., 214:295-304, 1986. 22) SAMPATH, T.K. and REDDI, A.H.:Importance of geometry of the extracellular matrix in endochondral bone differentiation;J. Cell. Biol., 98:2192-2197, 1984. 4) BLOCK, M.S. and KENT, J.N.:Healing of mandibular ridge augmentation using hydroxyapatite with and without autogenous bone in dogs;J. Oral Maxillofac. Surg., 43:3-7, 1985. 16) URIST, M.R.:β-Tricalcium phosphate delivery system for bone morphogenetic protein;Clin. Orthop. Relat. Res., 187:277-280, 1984. 1) JOHN, R.A., DORAN, E.R. and KARL, A.M.:The autogenous particulate cancellous bone marrow graft in alveolar clefts;Oral Surg., 51:588-591, 1981. 2) 黒田雅仁：下顎骨欠損への骨髄を含む海綿骨梁移植における骨新生と骨再構築機転に関する実験的研究；歯科学報，83：683-711，1983 11) URIST, M.R.:Bone formation by autoinduction;Science, 150:893-899, 1965. 21) WOZNEY, J.M., ROSEN, V., CELESTE, A.J., MITSOCK, L.M., WHITTERS, J.M., KRIZ, R.M., HEWICK, R.M. and WANG, E.A.:Novel regulators of bone formation:molecular clones and activities;Science, 242:1528-1534, 1988. 5) 村瀬博文，平 博彦，麻生智義，北村完二，山下徹朗，富田喜内，松崎弘明，谷内健司，和田敏亮，道谷弘之，額賀康之，金澤正昭，田中 収，永井教之：補綴前外科手術としてのハイドロキシアパタイトによる無歯顎顎堤形成法；日口外誌，33：62-72，1987 19) JIN, Q.-M., TAKITA, H., KOHGO, T., ATSUMI, K., ITOH, H. and KUBOKI, Y.:Effects of geometry of hydroxyapatite as a cell substratum in BMP-induced ectopic bone formation;J. Biomed. Mater. Res., 52:491-499, 2000. 9) ILARA, R.Z., ANTONIUS, L. and BRONKERSTEN, J.J.Histology of human alveolar bone regeneration with a porous tricalcium;Clin. Oral Impl. Res., 12:379-384, 2001. 15) SAMPATH, T.K. and REDDI, A.H.:Dissociative extraction and reconstitution of extracellular matrix compovents involved in local bone differentiation;Proc. Natl.Acad. Sci. USA, 78:7599-7603, 1981. 18) 村田, 勝：骨形成タンパク質(BMP)による細胞分化のマトリックス依存性―多孔質ヒドロキシアパタイトにおける直接骨形成の確認―；北海道歯誌，15：148-160，1994 8) 入江 修，室野井基夫，田中 牧，西野治邦，神田晶巳，小山宏樹，賀来 亨，中出 修：Tricalcium phosphateceramicを用いたsinus lift後の組織学的観察；日口腔インプラント誌，11：241-246，1998 20) WEIBEL, E.R.:Quantitation in morphology, possibilities and limits;Beitr. Pathol., 155:1-17, 1975. 12) URIST, M.R. and STRATES, B.S.:Bone morphogenetic protein;J. Dent. Res., 50:1392-1406, 1971. 23) BASSETT, C.A.L.:Influence of oxygen concentration and mechanical factors on differentiation of connective tissues in vitro;Nature, 190:460-461,1961. 14) 久保木芳徳：BMPの生物学，骨再建の原理；歯科ジャーナル，38：397-407，1993 |
| References_xml | – reference: 20) WEIBEL, E.R.:Quantitation in morphology, possibilities and limits;Beitr. Pathol., 155:1-17, 1975. – reference: 16) URIST, M.R.:β-Tricalcium phosphate delivery system for bone morphogenetic protein;Clin. Orthop. Relat. Res., 187:277-280, 1984. – reference: 4) BLOCK, M.S. and KENT, J.N.:Healing of mandibular ridge augmentation using hydroxyapatite with and without autogenous bone in dogs;J. Oral Maxillofac. Surg., 43:3-7, 1985. – reference: 6) 島田勝弘，陳 明裕，武 宣昭，内藤 勲，高橋信彰，岩田耕三，梅田正博，栗岡一人，川本博男，寺延 治，島田桂吉，川井隆夫：HAPとβ-TCPの骨伝導性および安定性に関する組織学的研究―家兎脛骨骨髄腔内移植実験の長期観察結果について―；日口腔インプラント誌，2：54-61，1989． – reference: 8) 入江 修，室野井基夫，田中 牧，西野治邦，神田晶巳，小山宏樹，賀来 亨，中出 修：Tricalcium phosphateceramicを用いたsinus lift後の組織学的観察；日口腔インプラント誌，11：241-246，1998． – reference: 21) WOZNEY, J.M., ROSEN, V., CELESTE, A.J., MITSOCK, L.M., WHITTERS, J.M., KRIZ, R.M., HEWICK, R.M. and WANG, E.A.:Novel regulators of bone formation:molecular clones and activities;Science, 242:1528-1534, 1988. – reference: 2) 黒田雅仁：下顎骨欠損への骨髄を含む海綿骨梁移植における骨新生と骨再構築機転に関する実験的研究；歯科学報，83：683-711，1983． – reference: 1) JOHN, R.A., DORAN, E.R. and KARL, A.M.:The autogenous particulate cancellous bone marrow graft in alveolar clefts;Oral Surg., 51:588-591, 1981. – reference: 18) 村田, 勝：骨形成タンパク質(BMP)による細胞分化のマトリックス依存性―多孔質ヒドロキシアパタイトにおける直接骨形成の確認―；北海道歯誌，15：148-160，1994． – reference: 13) WANG, E.A., ROSEN, V.D., ALESSANDRO, J.S.,BAUDUY, M., CORDES, P., HARADA, T., ISRAEL, D.A., HEWICK, R.M., KERNS, K.M., LAPAN, P., LUXENBERG, D.P., MCQUAID, D., MOUTSATSOS, LK., NOVE, J. and WOZNEY, J.M.:Recombinant human bone morphogenetic protein induces bone formation;Proc. Natl. Acad. Sci. USA, 87:2220-2224, 1990. – reference: 14) 久保木芳徳：BMPの生物学，骨再建の原理；歯科ジャーナル，38：397-407，1993． – reference: 17) URIST, M.R. and NILSSON, O.:Bone regeneration under the influence of a bone morphogenetic protein (BMP) beta tricalcium phosphate (TCP) composite inskull trephine defects in dogs;Clin. Orthop. Relat. Res., 214:295-304, 1986. – reference: 11) URIST, M.R.:Bone formation by autoinduction;Science, 150:893-899, 1965. – reference: 25) TSURUGA, E., TAKITA, H., ITOH, H., WAKISAKA, Y. and KUBOKI, Y.:Pore size of porous hydroxyapatite as the cell-substratum controls BMP-nduced osteogenesis;J.Biochem., 121:317-324, 1997. – reference: 3) 落合栄樹：自家新鮮海綿骨および同種脱脂凍結乾燥海綿骨の筋膜下移植における新鮮遊離骨膜・脱脂凍結乾燥骨膜の被包効果に関する実験的研究；日口外誌，38：1041-1054，1992． – reference: 12) URIST, M.R. and STRATES, B.S.:Bone morphogenetic protein;J. Dent. Res., 50:1392-1406, 1971. – reference: 22) SAMPATH, T.K. and REDDI, A.H.:Importance of geometry of the extracellular matrix in endochondral bone differentiation;J. Cell. Biol., 98:2192-2197, 1984. – reference: 24) BASSETT, C.A.L.:Current concepts of bone formation;J. Bone Joint Surg., 44-A:1217-1244, 1962. – reference: 23) BASSETT, C.A.L.:Influence of oxygen concentration and mechanical factors on differentiation of connective tissues in vitro;Nature, 190:460-461,1961. – reference: 5) 村瀬博文，平 博彦，麻生智義，北村完二，山下徹朗，富田喜内，松崎弘明，谷内健司，和田敏亮，道谷弘之，額賀康之，金澤正昭，田中 収，永井教之：補綴前外科手術としてのハイドロキシアパタイトによる無歯顎顎堤形成法；日口外誌，33：62-72，1987． – reference: 9) ILARA, R.Z., ANTONIUS, L. and BRONKERSTEN, J.J.Histology of human alveolar bone regeneration with a porous tricalcium;Clin. Oral Impl. Res., 12:379-384, 2001. – reference: 19) JIN, Q.-M., TAKITA, H., KOHGO, T., ATSUMI, K., ITOH, H. and KUBOKI, Y.:Effects of geometry of hydroxyapatite as a cell substratum in BMP-induced ectopic bone formation;J. Biomed. Mater. Res., 52:491-499, 2000. – reference: 15) SAMPATH, T.K. and REDDI, A.H.:Dissociative extraction and reconstitution of extracellular matrix compovents involved in local bone differentiation;Proc. Natl.Acad. Sci. USA, 78:7599-7603, 1981. – reference: 10) MIYAMOTO, S., TAKAOKA, K., OKADA, T., YOSHIKAWA, H., HASHIMOTO, J., SUZUKI, S. and ONO, K.:Polylactic acid-polyethylene glycol block copolymer;Clin. Orthop. Relat. Res., 294:333-343, 1993. – reference: 7) 小笠原健文，五百蔵一男，藤原寿彦，阿多史雄，白川禎則：アパタイトブロック長期填入例のCTによる検討 (抄)．日口腔インプラント誌，13：180，2000． |
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| SubjectTerms | bioabsorption biomimetic ceramics body fluid bodyfluid functionally graded HAp (fg-HAp) functionally graded HAp（fg-HAp） new bone formation rhBMP-2 |
| Subtitle | rhBMP-2による骨誘導 |
| Title | 生体模倣傾斜機能アパタイトの開発 |
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