再発発見のきっかけからみた乳癌術後フォローアップ法の検討
再発乳癌148例の発見のきっかけを分析した.局所胸壁再発では視触診62.1%, 自覚症状31.0%, 腫瘍マーカー異常6.9%, 所属リンパ節再発では視触診69.4%, 自覚症状13.9%, 腫瘍マーカー異常11.1%, 肺転移では腫瘍マーカー異常56.5%, 胸部X線写真21.7%, CT13.0%, 自覚症状8.7%, 胸膜転移では,自覚症状42.9%, 腫瘍マーカー異常35.7%, CT21.4%, 骨転移では自覚症状45.3%, 骨シンチグラム30.2%, 腫瘍マーカー異常20.8%, 肝転移ではCT53.8%, 腫瘍マーカー異常46.2%, 温存乳房再発では視触診76.3%, MMG...
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Published in | 日本臨床外科学会雑誌 Vol. 67; no. 10; pp. 2261 - 2266 |
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Main Authors | , , , , |
Format | Journal Article |
Language | Japanese |
Published |
日本臨床外科学会
25.10.2006
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ISSN | 1345-2843 1882-5133 |
DOI | 10.3919/jjsa.67.2261 |
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Abstract | 再発乳癌148例の発見のきっかけを分析した.局所胸壁再発では視触診62.1%, 自覚症状31.0%, 腫瘍マーカー異常6.9%, 所属リンパ節再発では視触診69.4%, 自覚症状13.9%, 腫瘍マーカー異常11.1%, 肺転移では腫瘍マーカー異常56.5%, 胸部X線写真21.7%, CT13.0%, 自覚症状8.7%, 胸膜転移では,自覚症状42.9%, 腫瘍マーカー異常35.7%, CT21.4%, 骨転移では自覚症状45.3%, 骨シンチグラム30.2%, 腫瘍マーカー異常20.8%, 肝転移ではCT53.8%, 腫瘍マーカー異常46.2%, 温存乳房再発では視触診76.3%, MMG7.7%, 自覚症状7.7%, 腫瘍マーカー異常7.7%であった.問診は,局所胸壁,所属リンパ節,胸膜,骨,脳転移,視触診は局所胸壁・所属リンパ節,温存乳房内再発,腫瘍マーカー測定は,肺,胸膜,骨,肝転移, CTは肺,胸膜,肝転移の発見に有効であった.乳癌術後フォローアップ法は,問診・視触診,腫瘍マーカー測定, CT撮影が望ましい. |
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AbstractList | 再発乳癌148例の発見のきっかけを分析した.局所胸壁再発では視触診62.1%, 自覚症状31.0%, 腫瘍マーカー異常6.9%, 所属リンパ節再発では視触診69.4%, 自覚症状13.9%, 腫瘍マーカー異常11.1%, 肺転移では腫瘍マーカー異常56.5%, 胸部X線写真21.7%, CT13.0%, 自覚症状8.7%, 胸膜転移では,自覚症状42.9%, 腫瘍マーカー異常35.7%, CT21.4%, 骨転移では自覚症状45.3%, 骨シンチグラム30.2%, 腫瘍マーカー異常20.8%, 肝転移ではCT53.8%, 腫瘍マーカー異常46.2%, 温存乳房再発では視触診76.3%, MMG7.7%, 自覚症状7.7%, 腫瘍マーカー異常7.7%であった.問診は,局所胸壁,所属リンパ節,胸膜,骨,脳転移,視触診は局所胸壁・所属リンパ節,温存乳房内再発,腫瘍マーカー測定は,肺,胸膜,骨,肝転移, CTは肺,胸膜,肝転移の発見に有効であった.乳癌術後フォローアップ法は,問診・視触診,腫瘍マーカー測定, CT撮影が望ましい. |
Author | 高橋, 弘昌 高橋, 将人 藤堂, 省 渡邊, 健一 佐々木, 文章 |
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References | 12) Boccardo F, Bruzzi P, Cionini L, et al: Appropriateness of the use of clinical and radiologic examinations and laboratory tests in the follow-up of surgically-treated breast cancer patients. Results of the Working Group on the Clinical Aspects of Follow-up. Ann Oncol 6 (Suppl 2): 57-59, 1995 13) Joseph E, Hyacinthe M, Lyman GH, et al: Evaluation of an intensive strategy for follow-up and surveillance of primary breast cancer. Ann Surg Oncol 5: 522-528, 1998 4) 榎本耕治,佐藤 宏,藤原 潔:再発の病態と術後追跡のあり方乳癌症例の血清 CA15-3と再発.乳癌の臨 4: 191-197, 1989 11) Krengli M, Pastore G, Maffei S: The importance of the follow-up in patients operated on for breast cancer. A retrospective analysis of 2482 cases. Minerva Med 84: 409-415, 1993 9) Rosselli Del Turco M, Palli D, Cariddi A, et al: Intensive diagnostic follow-up after treatment of primary breast cancer. A randomized trial. National Research Council Project on Breast Cancer follow-up. JAMA 271: 1593-1597, 1994 1) Rojas MP, Telano E, RussiA, et al: Follow-up strategies for women treated for early breast cancer. Cochrane Database Syst Rev 25: 1-21, 2005 17) Sato N, Hino M, Sano M: Detection of bone metastases in routine follow-up after treatment for primary breast cancer. Breast Cancer 10: 335-340, 2003 16) Khansur T, Haick A, Patel B, et al: Evaluation of bone scan as a screening work-up in primary and local-regional recurrence of breast cancer. Am J Clin Oncol 10: 167-170, 1987 2) 園尾博司,妹尾亘明:再発の病態と術後追跡のあり方乳癌の術後追跡.乳癌の臨 4: 167-180, 1989 3) 三浦重人:再発の病態と術後追跡のあり方術後追跡私の考え方.乳癌の臨 4: 181-190, 1989 5) Anan K, Mitsuyama S, Tamae K, et al: Postoperative follow-up of patients with early breast cancer: reappraisal of serum tumor markers. Surg Today 32: 13-18, 2002 8) Liverati A, Fossati R, Meyerowitz BE, et al: Impact of follow-up testing on survival and health-related quality of life in breast cancer patients. A multicenter randomized controlled trial, JAMA 271: 1587-1592, 1994 14) Imoto S, Jitsuiki Y: Detection of the first recurrence during intensive follow-up of breast cancer patients. Jpn J Clin Oncol 28: 597-600, 1998 7) Carlson RW, McCormick B: Update: NCCN breast cancer Clinical Practice Guidelines. J Natl Compr Canc Netw 3 (Suppl 1): S7-11, 2005 10) Liberati A: The GIVIO trial on the impact of follow-up care on survival and quality of life in breast cancer patients. Interdisciplinary Group for Cancer Evaluation. Ann Oncol 6(Suppl 2): 41-46, 1995 15) Ciatto S, Paconi P, Andreoli C, et al: Chest X-ray survey in the follow-up of breast cancerpatients. Br J Cancer 60:102-103, 1989 6) Smith TJ, Davidson NE, Schpira DV, et al: American Society of Clinical Oncology 1998 Update of Recommended Breast Cancer Surveillance Guidelines. J Clin Oncol 17: 1080-1082, 1998 18) Bast Jr RC, Ravdin P, Hayes DF, et al: 2000 Update of Recommendations for the Use of Tumor Markers in Breast ans Colorectal Cancer: Clinical Practice Guidelines of the American Society of Clinical Oncology. J Clin Oncol 19: 1865-1878, 2001 |
References_xml | – reference: 5) Anan K, Mitsuyama S, Tamae K, et al: Postoperative follow-up of patients with early breast cancer: reappraisal of serum tumor markers. Surg Today 32: 13-18, 2002 – reference: 3) 三浦重人:再発の病態と術後追跡のあり方術後追跡私の考え方.乳癌の臨 4: 181-190, 1989 – reference: 14) Imoto S, Jitsuiki Y: Detection of the first recurrence during intensive follow-up of breast cancer patients. Jpn J Clin Oncol 28: 597-600, 1998 – reference: 15) Ciatto S, Paconi P, Andreoli C, et al: Chest X-ray survey in the follow-up of breast cancerpatients. Br J Cancer 60:102-103, 1989 – reference: 8) Liverati A, Fossati R, Meyerowitz BE, et al: Impact of follow-up testing on survival and health-related quality of life in breast cancer patients. A multicenter randomized controlled trial, JAMA 271: 1587-1592, 1994 – reference: 9) Rosselli Del Turco M, Palli D, Cariddi A, et al: Intensive diagnostic follow-up after treatment of primary breast cancer. A randomized trial. National Research Council Project on Breast Cancer follow-up. JAMA 271: 1593-1597, 1994 – reference: 2) 園尾博司,妹尾亘明:再発の病態と術後追跡のあり方乳癌の術後追跡.乳癌の臨 4: 167-180, 1989 – reference: 12) Boccardo F, Bruzzi P, Cionini L, et al: Appropriateness of the use of clinical and radiologic examinations and laboratory tests in the follow-up of surgically-treated breast cancer patients. Results of the Working Group on the Clinical Aspects of Follow-up. Ann Oncol 6 (Suppl 2): 57-59, 1995 – reference: 11) Krengli M, Pastore G, Maffei S: The importance of the follow-up in patients operated on for breast cancer. A retrospective analysis of 2482 cases. Minerva Med 84: 409-415, 1993 – reference: 7) Carlson RW, McCormick B: Update: NCCN breast cancer Clinical Practice Guidelines. J Natl Compr Canc Netw 3 (Suppl 1): S7-11, 2005 – reference: 4) 榎本耕治,佐藤 宏,藤原 潔:再発の病態と術後追跡のあり方乳癌症例の血清 CA15-3と再発.乳癌の臨 4: 191-197, 1989 – reference: 16) Khansur T, Haick A, Patel B, et al: Evaluation of bone scan as a screening work-up in primary and local-regional recurrence of breast cancer. Am J Clin Oncol 10: 167-170, 1987 – reference: 18) Bast Jr RC, Ravdin P, Hayes DF, et al: 2000 Update of Recommendations for the Use of Tumor Markers in Breast ans Colorectal Cancer: Clinical Practice Guidelines of the American Society of Clinical Oncology. J Clin Oncol 19: 1865-1878, 2001 – reference: 1) Rojas MP, Telano E, RussiA, et al: Follow-up strategies for women treated for early breast cancer. Cochrane Database Syst Rev 25: 1-21, 2005 – reference: 13) Joseph E, Hyacinthe M, Lyman GH, et al: Evaluation of an intensive strategy for follow-up and surveillance of primary breast cancer. Ann Surg Oncol 5: 522-528, 1998 – reference: 6) Smith TJ, Davidson NE, Schpira DV, et al: American Society of Clinical Oncology 1998 Update of Recommended Breast Cancer Surveillance Guidelines. J Clin Oncol 17: 1080-1082, 1998 – reference: 17) Sato N, Hino M, Sano M: Detection of bone metastases in routine follow-up after treatment for primary breast cancer. Breast Cancer 10: 335-340, 2003 – reference: 10) Liberati A: The GIVIO trial on the impact of follow-up care on survival and quality of life in breast cancer patients. Interdisciplinary Group for Cancer Evaluation. Ann Oncol 6(Suppl 2): 41-46, 1995 |
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Snippet | 再発乳癌148例の発見のきっかけを分析した.局所胸壁再発では視触診62.1%, 自覚症状31.0%, 腫瘍マーカー異常6.9%, 所属リンパ節再発では視触診69.4%, 自覚症状13.9%, 腫瘍マーカー異常11.1%, 肺転移では腫瘍マーカー異常56.5%, 胸部X線写真21.7%, CT13.0%,... |
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SubjectTerms | 乳癌 再発乳癌 術後フォローアップ 術後経過観察 術後追跡 |
Title | 再発発見のきっかけからみた乳癌術後フォローアップ法の検討 |
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