多発性骨髄腫の病態と臨床
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| Published in | 日本内科学会雑誌 Vol. 81; no. 9; pp. 1335 - 1347 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | Japanese |
| Published |
一般社団法人 日本内科学会
1992
|
| Online Access | Get full text |
| ISSN | 0021-5384 1883-2083 |
| DOI | 10.2169/naika.81.1335 |
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| Author | 藏本, 淳 |
|---|---|
| Author_xml | – sequence: 1 fullname: 藏本, 淳 organization: 広島大学原爆放射能医学研究所臨床第一(内科)研究部門 |
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| EndPage | 1347 |
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| References | 9) Iwato K, et al: Separation of human myeloma cells from bone marrow aspirates in multiple myeloma and their proliferation and M-protein secretion in vitro. Blood 72: 562, 1988. 7) Ichimaru M, et al: Multiple myeloma among atomic bomb survivors in Hiroshima and Nagasaki by marrow dose, 1950-1976. J NCI 69: 323, 1982. 23) Yasukawa K, et al: Structure and expression of human B cell stimulatory factor 2(BSF-2/IL-6) gene. EMBO J 6: 2939, 1987. 28) Asaoku H, et al: Decrease in BSF-2/IL-6 response in advanced cases of multiple myeloma. Blood 72: 429. 1988. 12) Namba Y, et al: Immunocytology of cultured IgM-forming cells of mouse. I. Requirement of phagocytic cell factor for the growth of IgMforming tumor cells in tissue culture. J Immunol 190: 1193, 1972. 14) van Snick J, et al: Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas. Proc Natl Acad Sci USA 83: 9679, 1986. 22) Suematsu S, et al: IgG1 plasmacytosis in interleukin 6 transgenic mice. Proc Natl Acad Sci USA 86: 7547, 1989. 31) Klein G, et al: Specific chromosomal translocations and the genesis of B-cell derived tumors in mice and man. Cell 32: 311, 1983. 4) Mundy GR, et al: Bone-resorbing activity in supernatants from lymphoid cell lines. New Engl J Med 290: 867, 1974. 21) Sporn MB, et al: Autocrine secretion and malignant transformation of cells. New Engl J Med 303: 878, 1980. 1) Kawano M, et al: Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature 332: 83, 1988. 5) Kuramoto A: Cytokines cast new insight into myeloma therapy. Jpn J Med 30: 395, 1991. 37) Springer TA, et al; Adhesion receptors of the immune system. Nature 346: 425, 1990. 2) Hirano T, et al: Complementary DNA for anovel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 324: 73, 1986. 18) Hibi M, et al: Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell 63: 1149, 1990. 39) Greipp PR, et al: Multiple myeloma: Significance of plasmablastic subtype in morphological classification. Blood 65: 305, 1985. 32) Selvanayagam P, et al: Alteration and abnormal expression of the c-myc oncogene in human multiple myeloma. Blood 71: 30, 1988. 33) Nobuyoshi M, et al: Increased expression of the c-myc gene may be related to the aggressive transformation of human myeloma cells. Br T Haematol 77: 523. 1991. 24) Tanabe O, et al: Genomic structure of the murine IL-6 gene: High degree conservation of potential regulatory sequences between mouse and human. J Immunol 141: 3875, 1988. 35) Garrett R, et al: Production of lymphotoxin, a bone-resorbing cytokine, cultured human myeloma cells. New Engl J Med 317: 526, 1987. 38) Kawano M, et al: Homotypic cell aggregation of human myeloma cells with ICAM-1 and LFA-1 molecules. Br J Haematol 79: 583, 1991. 17) Yamasaki K, et al: Cloning and expression of the human interleukin-6 (BSF-2/IFNβ2) receptor. Science 241: 825, 1988. 40) Kawano MM, et al: Differentiated expression of VLA-5 accounting for the heterogeneity of myeloma cells in human myelomas. Blood (in press). 15) Kawano M, et al: Interleukin 1 accelerates autocrine growth of myeloma cells through interleukin 6 in human myeloma. Blood 73: 2145, 1989. 20) Klein B, et al: Paracrine rather than autocrine regulation of myeloma cell growth and differentiation by interleukin-6. Blood 73: 517, 1989. 29) Barlogie B, et al: High serum levels of lactic dehydrogenase identify a high grade lymphoma-like myeloma. Ann Intern Med 110: 521, 1989. 36) Kawano M, et al: Interleukin-1 beta rather than lymphotoxin as the major bone resorbing activity in human multiple myeloma. Blood 73: 1646, 1989. 6) Cuzick J, et al: Radiation-induced myelomatosis. New Engl J Med 304: 204, 1981. 16) Jourdan M, et al: IFN-α induces autocrine production of IL-6 in myeloma cell lines. J Immunol 147: 4402, 1991. 30) Barlogie B, et al: Plasma cell myeloma new biological insights and advances in therapy. Blood 73: 865, 1989. 26) Isshiki H, et al: Constitutive and interleukin1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene. Mol Cell Biol 10: 2757, 1990. 41) Tanaka H, et al: Sensitive inhibitory effect of interferon-alpha on M-protein secretion of human myeloma cells. Blood 74: 1718, 1989. 8) Neriishi K, et al: M-proteinemia in A-bomb survivors and controls, Hiroshima and Nagasaki, Radiation Res. (submitted 3) Kishimoto T, et al: The biology of interleukin-6. Blood 74: 1, 1989. 10) Kawano M, et al: Pathogenesis of myeloma and its regualtion by cytokines. Acta Haematol Jpn 49: 1740, 1986. 25) Akira S, et al: A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J 9: 1897, 1990. 34) Sakai A, et al: Interleukin-6 produced by renal-cell carcinoma cells and progression of multiple myeloma. New Engl J Med 324: 1893, 1991. 27) Tanabe O, et al: Expression of NF-IL-6, a transcriptional activator of IL-6 gene, in human blood cells and myeloma cells. Blood 76: 375, 1990. 42) Klein B, et al: Interleukin-6 is the central tumor growth factor in vitro and in vivo in multiple myeloma. Eur Cytokine Net 1: 193, 1990. 11) Potter M, et al: Induction of plasma cell neoplasms in strain Balb/c mice with mineral oil and mineral oil adjuvants. Nature 193: 1086, 1962. 13) Nordan RP, et al: A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro. Science 233: 566, 1986. 19) Ishikawa H, et al: IL-6 receptor expression on human myeloma cells. Blood 76: 353, 1990. |
| References_xml | – reference: 35) Garrett R, et al: Production of lymphotoxin, a bone-resorbing cytokine, cultured human myeloma cells. New Engl J Med 317: 526, 1987. – reference: 30) Barlogie B, et al: Plasma cell myeloma new biological insights and advances in therapy. Blood 73: 865, 1989. – reference: 6) Cuzick J, et al: Radiation-induced myelomatosis. New Engl J Med 304: 204, 1981. – reference: 27) Tanabe O, et al: Expression of NF-IL-6, a transcriptional activator of IL-6 gene, in human blood cells and myeloma cells. Blood 76: 375, 1990. – reference: 17) Yamasaki K, et al: Cloning and expression of the human interleukin-6 (BSF-2/IFNβ2) receptor. Science 241: 825, 1988. – reference: 37) Springer TA, et al; Adhesion receptors of the immune system. Nature 346: 425, 1990. – reference: 2) Hirano T, et al: Complementary DNA for anovel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin. Nature 324: 73, 1986. – reference: 41) Tanaka H, et al: Sensitive inhibitory effect of interferon-alpha on M-protein secretion of human myeloma cells. Blood 74: 1718, 1989. – reference: 1) Kawano M, et al: Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas. Nature 332: 83, 1988. – reference: 4) Mundy GR, et al: Bone-resorbing activity in supernatants from lymphoid cell lines. New Engl J Med 290: 867, 1974. – reference: 26) Isshiki H, et al: Constitutive and interleukin1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene. Mol Cell Biol 10: 2757, 1990. – reference: 38) Kawano M, et al: Homotypic cell aggregation of human myeloma cells with ICAM-1 and LFA-1 molecules. Br J Haematol 79: 583, 1991. – reference: 39) Greipp PR, et al: Multiple myeloma: Significance of plasmablastic subtype in morphological classification. Blood 65: 305, 1985. – reference: 9) Iwato K, et al: Separation of human myeloma cells from bone marrow aspirates in multiple myeloma and their proliferation and M-protein secretion in vitro. Blood 72: 562, 1988. – reference: 19) Ishikawa H, et al: IL-6 receptor expression on human myeloma cells. Blood 76: 353, 1990. – reference: 23) Yasukawa K, et al: Structure and expression of human B cell stimulatory factor 2(BSF-2/IL-6) gene. EMBO J 6: 2939, 1987. – reference: 40) Kawano MM, et al: Differentiated expression of VLA-5 accounting for the heterogeneity of myeloma cells in human myelomas. Blood (in press). – reference: 20) Klein B, et al: Paracrine rather than autocrine regulation of myeloma cell growth and differentiation by interleukin-6. Blood 73: 517, 1989. – reference: 3) Kishimoto T, et al: The biology of interleukin-6. Blood 74: 1, 1989. – reference: 22) Suematsu S, et al: IgG1 plasmacytosis in interleukin 6 transgenic mice. Proc Natl Acad Sci USA 86: 7547, 1989. – reference: 25) Akira S, et al: A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family. EMBO J 9: 1897, 1990. – reference: 36) Kawano M, et al: Interleukin-1 beta rather than lymphotoxin as the major bone resorbing activity in human multiple myeloma. Blood 73: 1646, 1989. – reference: 10) Kawano M, et al: Pathogenesis of myeloma and its regualtion by cytokines. Acta Haematol Jpn 49: 1740, 1986. – reference: 24) Tanabe O, et al: Genomic structure of the murine IL-6 gene: High degree conservation of potential regulatory sequences between mouse and human. J Immunol 141: 3875, 1988. – reference: 8) Neriishi K, et al: M-proteinemia in A-bomb survivors and controls, Hiroshima and Nagasaki, Radiation Res. (submitted) – reference: 5) Kuramoto A: Cytokines cast new insight into myeloma therapy. Jpn J Med 30: 395, 1991. – reference: 21) Sporn MB, et al: Autocrine secretion and malignant transformation of cells. New Engl J Med 303: 878, 1980. – reference: 34) Sakai A, et al: Interleukin-6 produced by renal-cell carcinoma cells and progression of multiple myeloma. New Engl J Med 324: 1893, 1991. – reference: 28) Asaoku H, et al: Decrease in BSF-2/IL-6 response in advanced cases of multiple myeloma. Blood 72: 429. 1988. – reference: 42) Klein B, et al: Interleukin-6 is the central tumor growth factor in vitro and in vivo in multiple myeloma. Eur Cytokine Net 1: 193, 1990. – reference: 13) Nordan RP, et al: A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro. Science 233: 566, 1986. – reference: 29) Barlogie B, et al: High serum levels of lactic dehydrogenase identify a high grade lymphoma-like myeloma. Ann Intern Med 110: 521, 1989. – reference: 14) van Snick J, et al: Purification and NH2-terminal amino acid sequence of a T-cell-derived lymphokine with growth factor activity for B-cell hybridomas. Proc Natl Acad Sci USA 83: 9679, 1986. – reference: 16) Jourdan M, et al: IFN-α induces autocrine production of IL-6 in myeloma cell lines. J Immunol 147: 4402, 1991. – reference: 11) Potter M, et al: Induction of plasma cell neoplasms in strain Balb/c mice with mineral oil and mineral oil adjuvants. Nature 193: 1086, 1962. – reference: 12) Namba Y, et al: Immunocytology of cultured IgM-forming cells of mouse. I. Requirement of phagocytic cell factor for the growth of IgMforming tumor cells in tissue culture. J Immunol 190: 1193, 1972. – reference: 32) Selvanayagam P, et al: Alteration and abnormal expression of the c-myc oncogene in human multiple myeloma. Blood 71: 30, 1988. – reference: 7) Ichimaru M, et al: Multiple myeloma among atomic bomb survivors in Hiroshima and Nagasaki by marrow dose, 1950-1976. J NCI 69: 323, 1982. – reference: 18) Hibi M, et al: Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell 63: 1149, 1990. – reference: 31) Klein G, et al: Specific chromosomal translocations and the genesis of B-cell derived tumors in mice and man. Cell 32: 311, 1983. – reference: 33) Nobuyoshi M, et al: Increased expression of the c-myc gene may be related to the aggressive transformation of human myeloma cells. Br T Haematol 77: 523. 1991. – reference: 15) Kawano M, et al: Interleukin 1 accelerates autocrine growth of myeloma cells through interleukin 6 in human myeloma. Blood 73: 2145, 1989. |
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| Title | 多発性骨髄腫の病態と臨床 |
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