THE COMBINATION EFFECT OF TRIMETHOPRIM AND SULFAMETHOXAZOLE AGAINST ANAEROBES

Bacteriostatic effect has been variously affected against anaerobesly to trimethoprim (TMP) and sulfamethoxazole (SMX) combination drug by inoculum size. We think that sensitive anaerobes to TMP or SMX have the enhanced activity by the combination of TMP and SMX, while high resistant anaerobes have...

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Published inCHEMOTHERAPY Vol. 21; no. 2; pp. 128 - 136
Main Authors KAMIYA, HAROKO, WATANABE, KUNITOMO, NINOMIYA, KEIU, UENO, KAZUE, SUZUKI, SHOICHIRO
Format Journal Article
LanguageEnglish
Japanese
Published Japanese Society of Chemotherapy 1973
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Abstract Bacteriostatic effect has been variously affected against anaerobesly to trimethoprim (TMP) and sulfamethoxazole (SMX) combination drug by inoculum size. We think that sensitive anaerobes to TMP or SMX have the enhanced activity by the combination of TMP and SMX, while high resistant anaerobes have not.
AbstractList Bacteriostatic effect has been variously affected against anaerobesly to trimethoprim (TMP) and sulfamethoxazole (SMX) combination drug by inoculum size. We think that sensitive anaerobes to TMP or SMX have the enhanced activity by the combination of TMP and SMX, while high resistant anaerobes have not.
Author UENO, KAZUE
WATANABE, KUNITOMO
NINOMIYA, KEIU
SUZUKI, SHOICHIRO
KAMIYA, HAROKO
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  fullname: NINOMIYA, KEIU
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  fullname: SUZUKI, SHOICHIRO
  organization: Department of Bacteriology, Gifu University, School of Medicine
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References 2) 小酒井望, 鈴木祥一郎 : 嫌気性菌と嫌気性菌症. 医学書院 1968
1) HITCHINGS, G. H. : The synergy of Trimethoprim and Sulphonamides proceedings of a Conferance held on Friday, May 9, 1969, at the Royal College of Physicians, London.
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Title THE COMBINATION EFFECT OF TRIMETHOPRIM AND SULFAMETHOXAZOLE AGAINST ANAEROBES
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