THE COMBINATION EFFECT OF TRIMETHOPRIM AND SULFAMETHOXAZOLE AGAINST ANAEROBES

Bacteriostatic effect has been variously affected against anaerobesly to trimethoprim (TMP) and sulfamethoxazole (SMX) combination drug by inoculum size. We think that sensitive anaerobes to TMP or SMX have the enhanced activity by the combination of TMP and SMX, while high resistant anaerobes have...

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Published inCHEMOTHERAPY Vol. 21; no. 2; pp. 128 - 136
Main Authors KAMIYA, HAROKO, WATANABE, KUNITOMO, NINOMIYA, KEIU, UENO, KAZUE, SUZUKI, SHOICHIRO
Format Journal Article
LanguageEnglish
Japanese
Published Japanese Society of Chemotherapy 1973
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Summary:Bacteriostatic effect has been variously affected against anaerobesly to trimethoprim (TMP) and sulfamethoxazole (SMX) combination drug by inoculum size. We think that sensitive anaerobes to TMP or SMX have the enhanced activity by the combination of TMP and SMX, while high resistant anaerobes have not.
ISSN:0009-3165
1884-5894
DOI:10.11250/chemotherapy1953.21.128